Results 91 to 100 of about 346,800 (296)

Candida albicans pathogenicity mechanisms [PDF]

, 2013
Peer reviewedPublisher ...
Alonso-Monge R, Braun BR, Csank C, De Bernardis F, Diez-Orejas R, Fonzi WA, Hube B, Hwang CS, Mühlschlegel FA, Sorger PK, Wysong DR   +10 more
core   +1 more source

Transducers Across Scales and Frequencies: A System‐Level Framework for Multiphysics Integration and Co‐Design

Advanced Materials Technologies, EarlyView.
Transducers convert physical signals into electrical and optical representations, yet each mechanism is bounded by intrinsic trade‐offs across bandwidth, sensitivity, speed, and energy. This review maps transduction mechanisms across physical scale and frequency, showing how heterogeneous integration and multiphysics co‐design transform isolated ...
Aolei Xu, Mengyao Xiao, Zhouli Sui, Yinpeng Wang, Daoye Zheng, Yuxin Liu, Luwei Wang, Huajun Liu, Chengkuo Lee   +8 more
wiley   +1 more source

The Fungal CYP51s: Their Functions, Structures, Related Drug Resistance, and Inhibitors

Frontiers in Microbiology, 2019
CYP51 (Erg11) belongs to the cytochrome P450 monooxygenase (CYP) superfamily and mediates a crucial step of the synthesis of ergosterol, which is a fungal-specific sterol. It is also the target of azole drugs in clinical practice.
Jingxiang Zhang, Liping Li, Liping Li, Quanzhen Lv, Lan Yan, Yan Wang, Yuanying Jiang, Yuanying Jiang, Yuanying Jiang   +8 more
doaj   +1 more source

N-termini of fungal CSL transcription factors are disordered, enriched in regulatory motifs and inhibit DNA binding in fission yeast. [PDF]

PLoS ONE, 2011
CSL (CBF1/RBP-Jκ/Suppressor of Hairless/LAG-1) transcription factors are the effector components of the Notch receptor signalling pathway, which is critical for metazoan development.
Martin Převorovský, Sophie R Atkinson, Martina Ptáčková, Janel R McLean, Kathleen Gould, Petr Folk, František Půta, Jürg Bähler   +7 more
doaj   +1 more source

Molecular analysis of the early interaction between the grapevine flower and Botrytis cinerea reveals that prompt activation of specific host pathways leads to fungus quiescence [PDF]

, 2017
Grape quality and yield can be impaired by bunch rot, caused by the necrotrophic fungus Botrytis cinerea. Infection often occurs at flowering, and the pathogen stays quiescent until fruit maturity.
Agudelo-Romero, Alkan, Amselem, Asselbergh, Bhuiyan, Birkenbihl, Blanco-Ulate, Boller, Bradley, Brutus, Caffall, Cantu, Choquer, Coertze, Conesa, Costa, Dadakova, Dalmais, De Cremer, Deytieux-Belleau, Du, Eichorn, Elmer, Espino, Favaron, Giannakis, Gilbert, Godfrey, Goetz, Grimplet, Guetsky, Hammerbacher, Hellemans, Höll, Jaillon, Jarvis, Jarvis, Jeandet, Jersch, Kan, Kan, Kan, Keller, Kelloniemi, Kemmerling, Kretschmer, Langcake, Law, Lebel, Lee, Leroch, Leroch, Liao, Liao, Lijavetzky, Liu, Malacarne, Marrs, Martin, McClellan, McNicol, Merz, Mlikota-Gabler, Mohnen, Monteiro, Moretto, Mullins, Nagpala, Nair, Naoumkina, Noda, Padgett, Pezet, Pezet, Prusky, Prusky, Prusky, Puhl, Rieu, Rolke, Rossi, Ruijter, Schouten, Schouten, Schumacher, Schumacher, Shaw, Smith, Smyth, Thimm, Vandesompele, Vannozzi, Velasco, Volodarsky, Vrhovsek, Waite, Weng, Wiermer, Williamson, Williamson, Zhang, Zhang, Zhao   +102 more
core   +1 more source

Consumed by Abdominal Distention

Arthritis Care &Research, EarlyView.
Abimbola Fadairo‐Azinge, James Grenert, Brian Haas, Mary Margaretten   +3 more
wiley   +1 more source

Unlocking the Potential of MXene‐Based Electrochemical Biosensors: A Review of Biofunctionalization Strategies and Biosensing Principles

Advanced Materials Technologies, EarlyView.
ABSTRACT Electrochemical biosensors enable the accurate and timely detection of clinical biomarkers, improving healthcare and precision medicine. MXene nanosheets, a class of 2D transition metal carbides, nitrides, and carbonitrides, are promising materials for developing next‐generation electrochemical biosensors due to their unique physicochemical ...
Muhsin Ali, Sharat Chandra Barman, Isobel Steer, Aya H. Alshareef, Dana Alsulaiman   +4 more
wiley   +1 more source

A Bright Future for Fluorescence Imaging of Fungi in Living Hosts

Journal of Fungi, 2019
Traditional in vivo investigation of fungal infection and new antifungal therapies in mouse models is usually carried out using post mortem methodologies. However, biomedical imaging techniques focusing on non-invasive techniques using bioluminescent and
Ambre F. Chapuis, Elizabeth R. Ballou, Donna M. MacCallum   +2 more
doaj   +1 more source

Farnesyltransferase Deficiency in Cardiomyocytes Initiates Senescence and Contributes to Cardiac Fibrosis

Advanced Science, EarlyView.
Lipid overload suppresses SREBF2‐mediated FNTB expression, leading to defective Lamin A maturation and nuclear envelope instability. This nuclear catastrophe triggers a pro‐fibrotic senescence program in cardiomyocytes. Notably, restoring nuclear integrity via AAV9‐based gene therapy effectively attenuates cardiac remodeling, identifying the ...
Yuxiao Chen, Lian Lou, Xuan Zhang, Lin Yan, Qi Zhang, Wen Shi, Jie Ding, Xu Lin, Rong Jiang, Shuo Liu, Thida Sok, Pengli Wang, Yun Mou, Jie Han, Shenjiang Hu, Xiaogang Guo, Jian Yang   +16 more
wiley   +1 more source

Fungal Secretome Database: Integrated platform for annotation of fungal secretomes

BMC Genomics, 2010
Background Fungi secrete various proteins that have diverse functions. Prediction of secretory proteins using only one program is unsatisfactory. To enhance prediction accuracy, we constructed Fungal Secretome Database (FSD).
Park Jongsun, Choi Jaeyoung, Kim Donghan, Jung Kyongyong, Kang Seogchan, Lee Yong-Hwan   +5 more
doaj   +1 more source