Results 111 to 120 of about 208,833 (298)
A Cationic Supramolecule With Potent Antifungal Activity, Single‐Species Selectivity, and Strong Synergy With Echinocandins
Advanced Science, EarlyView.We introduce a new membrane‐active antifungal design, Gua‐SMACS‐16, that exhibits high potency and single‐species selectivity for C. tropicalis while sparing other close species in the Candida genus. Moreover, when combining with caspofungin, a clinical antifungal drug inhibiting 1,3‐β‐glucan synthase, they exhibit ultra‐strong synergy across a panel ...Tianjiao Dai, Adrielle Xianwen Chen, Eve Wai Ling Chow, Li Mei Pang, Jianguo Li, Chandra Shekhar Verma, Stefan H. Oehlers, Yue Wang, Ning Li +8 morewiley +1 more sourceA Virus‐Inducible E3–RLCK–MADS Module Coordinates Suppression of Plant Immunity and Fertility in Rice
Advanced Science, EarlyView.ABSTRACT
Viruses often hijack host developmental programs to promote infection, but the mechanistic links between reproductive regulation and antiviral immunity remain incompletely understood. Here, we identify a virus‐triggered hierarchical degradation cascade that links antiviral immunity and fertility regulation in rice. We show that the rice grassy Yuansheng Wu, Fengling Wu, Shiting Huang, Denglu Yang, Xin Lei, Xue Zhang, Na Liu, Peng Gan, Chuan Li, Jie Zhang, Ming Wu, Qingxiao Jia, Shanshan Zhao, Jianguo Wu +13 morewiley +1 more sourceA first genome assembly of the barley fungal pathogen Pyrenophora teres f. teres
, 2011 Background: Pyrenophora teres f. teres is a necrotrophic fungal pathogen and the cause of one of barley's most important diseases, net form of net blotch.Ellwood, S.R., Syme, R.A., Liu, Z.H., Friesen, T.L., Moffat, C.S., Oliver, R.P., Keiper, F., Lai, Z.B., Hane, J.K. +8 morecore Finished Genome of the Fungal Wheat Pathogen Mycosphaerella graminicola Reveals Dispensome Structure, Chromosome Plasticity, and Stealth Pathogenesis
, 2011 The plant-pathogenic fungus Mycosphaerella graminicola (asexual stage: Septoria tritici) causes septoria tritici blotch, a disease that greatly reduces the yield and quality of wheat.van de Geest, HC, Rahim Mehrabi, de Vries, Ronald P., Dehal Paramvir, Donzelli Bruno, Conde-Ferràez, Laura, Stefano F F Torriani, Kema Gert H. J., Roeland C H J van Ham, Goodwin, S. B., Lombard, V., Nap Jan P. H., Ware, SB, Henrissat, B., Cools Hans J., Waalwijk, C, Oliver, R.P., Wiebenga, A., Wittenberg, Alexander HJ, Hane, James K., Kourmpetis Yiannis, De Wit, P., Maliepaard, C., Schouten, H., Jason J. Rudd, Goodwin, SB, Donzelli, B., Sarah B Ware, Ware Sarah B., Grigoriev, I.V., Kema, GHJ, Henk J Schouten, Van der Lee, Theo AJ, Stephen B. Goodwin, Schouten, HJ, Wittenberg, A. H. J., Foster, Andrew J, Theo A. J. Van der Lee, Jan P H Nap, Churchill, A.C.L., Lindquist, Erika, Kourmpetis, Y., de Wit, P.J.G.M., Hane James K., Donzelli, B, Aerts, Andrea, Churchill, Alice CL, M’Barek, Sarrah Ben, Charles F Crane, Ponomarenko, A., Ioannis Stergiopoulos, Andrew J. Foster, Hane, J.K., Foster, A.J., Laura Conde-Ferràez, Adilson K Kobayashi, Van Der Lee, T. A. J., Bruno Donzelli, Kilian Andrzej, Wiebenga, A, Kilian, A, Bowler, J., Bristow, J., Igor V Grigoriev, Pedro M Coutinho, Wittenberg, AHJ, Zwiers, L.H., Roeland C. H. J. van Ham, Foster, Andrew J., Cools, H.J., Ware, Sarah B, Chris Maliepaard, Foster Andrew J., Dehal, P, Dehal, Paramvir, Stefano F. F. Torriani, Ware, Sara B, Jane Grimwood, van der Burgt Ate, Kourmpetis, Yiannis, Goodwin, Stephen B., Rudd Jason J., Csukai Michael, Van der Lee, TAJ, Kim E Hammond-Kosack, Bailey Andy, Cees Waalwijk, Ware, Sarah B., Andy Bailey, Canto-Canché Blondy, Kobayashi, Adilson K., van de Geest, Henri C., Conde-Ferràez, L, Lindquist, E, Nap, Jan P.H., Burt Bluhm, Kilan, Andrzej, Maliepaard, Chris, Lindquist Erika, Hans J. Cools, Aerts, A, Edda Koopmann, Stephen B Goodwin, Bowler, Judith, Tu, H., Canto-Canché, B, van der Burgt, A., M\u27Barek, Sarrah Ben, Maliepaard, C, Hammond-Kosack Kim E., Koopmann, E, Martins, Natalia, Koopmann Edda, Paramvir Dehal, Wittenberg, Alexander H. J., Waalwijk, Cees, Bowler Judith, Hammond-Kosack, K.E., Foster, AJ, Dehal, P., Gert H J Kema, Dhillon Braham, Harris Shapiro, Wiebenga, Ad, Cools, Hans J., Geest, H.C., van de, Vries, R.P., de, Kim E. Hammond-Kosack, Lombard Vincent, Torriani Stefano F. F., Grigoriev Igor V., Koopmann, Edda, Lombard, V, Kobayashi, AK, van der Burgt, A, James K Hane, Coutinho, P.M., Ponomarenko, A, Crane, Charles F., M'Barek, S., Ben, Crane, C.F., Antoniw, J, Bristow, J, Schouten, Henk J., Antoniw, John, Gert H. J. Kema, Van der Lee, Theo A. J., Martins, N., Torriani, S.F.F., Ate van der Burgt, Hank Tu, Cools, Hans J, Rudd, J. J., Churchill, ACL, Goodwin, S.B., Csukai, Michael, Coutinho, P. M., Foster, A. J., Charles F. Crane, Grigoriev, IV, Pierre De Wit, Asaf Salamov, Grimwood, J, Henk J. Schouten, Crane, C. F., Antoniw, J. F., De Wit Pierre, Stergiopoulos, I., Henri C. van de Geest, Salamov, A., Salamov Asaf, Kobayashi, A.K., Oliver, RP, Coutinho, Pedro M., Schouten, H.J., Ware, S.B., Pedro M. Coutinho, Bailey, A., Goodwin Stephen B., Grimwood Jane, Schouten Henk J., van Ham, Roeland C.H.J., Mehrabi, R, Churchill, Alice C.L., Arnold Kuzniar, Oliver, Richard P, Lee, T.A.J., van der, van Ham, Roeland CHJ, Henrissat, Bernard, Kema, G.H.J., James K. Hane, de Wit, P, Alice C L Churchill, Van der Lee, Theo A.J., Yiannis Kourmpetis, Maliepaard, C.A., Churchill, Alice C. L., Oliver, Richard P., Schmutz, Jeremy, Kobayashi Adilson K., Richard P Oliver, Alice C. L. Churchill, Kema, Gert H.J., Conde-Ferràez, L., de Vries Ronald P., Van der Lee, T.A.J., Crane Charles F., M'Barek, SB, Grimwood, Jane, Kilian, Andrzej, Antoniw, J., Maliepaard Chris, Hammond-Kosack, K. E., Martins, N, Grigoriev, Igor V, Rudd, J.J., Coutinho Pedro M., Jim Bristow, Wittenberg Alexander H. J., Nap, J.P.H., John Antoniw, van der Burgt, Ate, Henrissat, B, Torriani, SFF, Wiebenga Ad, Lombard, Vincent, Rudd, Jason J, Ad Wiebenga, van de Geest, Henri C, Andrea Aerts, Martins Natalia, Koopmann, E., Bernard Henrissat, Kuzniar Arnold, Bluhm, Burt, Shapiro, H., Donzelli, Bruno, Hans J Cools, Antoniw John, Wittenberg, Alexander H.J., Churchill, A. C. L., Bristow, Jim, Vincent Lombard, van de Geest Henri C., Shapiro, Harris, Van De Geest, H. C., Alexander H. J. Wittenberg, Hane, James K, Bowler, J.M., Henri C van de Geest, Bluhm, B., Mehrabi Rahim, Waalwijk Cees, Adilson K. Kobayashi, Nap, Jan P. H., Ham, R.C.H.J., van, Ben M'Barek Sarrah, Mehrabi, Rahim, Jeremy Schmutz, Aerts Andrea, Schouten, Henk J, Bristow Jim, Canto-Canché, B., Blondy Canto-Canché, Hammond-Kosack, Kim E, Braham Dhillon, van de Geest, H.C., Stergiopoulos Ioannis, Schmutz, J, Jason J Rudd, Bluhm, B, Hane, J. K., Van Ham, R. C. H. J., Nap, JPH, Crane, CF, Stergiopoulos, I, Alexander H J Wittenberg, Salamov, Asaf, Nap, Jan PH, van Ham, Roel C. H. J., Shapiro Harris, Schmutz, J., Michael Csukai, de Vries, RP, van Ham Roeland C. H. J., Zwiers, Lute-Harm, Torriani, Stefano F.F., Judith Bowler, Dhillon, B., Burgt, A., van der, Sarrah Ben M'barek, Salamov, A, Crane, Charles F, Kobayashi, Adilson K, Richard P. Oliver, Goodwin, Stephen B, Ponomarenko Alisa, Bowler, J, Bailey, Andy, Natalia Martins, van Ham, RCHJ, Tu Hank, Coutinho, PM, Kourmpetis, Y, Bluhm Burt, Zwiers, L-H, Hane, JK, Csukai, M, de Vries, Ronald P, M'Barek, Sarrah B., Oliver Richard P., Geest, H.G., Van der Lee Theo A. J., Cools, HJ, Alisa Ponomarenko, Aerts, A., Andrzej Kilian, Zwiers Lute-Harm, Grigoriev, Igor V., Csukai, M., Henrissat Bernard, Dhillon, Braham, Kilian, A., Wittenberg, A.H.J., Kema, Gert. H. J., Rudd, JJ, Ben M'Barek, S., Wit, P.J.G.M., de, Tu, H, Conde-Ferràez Laura, Lindquist, E., Waalwijk, C., Lute-Harm Zwiers, Erika Lindquist, Mehrabi, A., Kuzniar, A, Dhillon, B, De Wit, Pierre, Canto-Canché, Blondy, Rudd, Jason J., Ponomarenko, Alisa, Coutinho, Pedro M, Ronald P de Vries, van Ham, R.C.H.J., Andrew J Foster, Shapiro, H, Hammond-Kosack, KE, Mehrabi, R., Torriani, Stefano FF, Schmutz Jeremy, Kuzniar, A., Kema, Gert HJ, M'barek, Sarrah Ben, Bailey, AM, Hammond-Kosack, Kim E., Grimwood, J., Jan P. H. Nap, de Vries, R.P., Stergiopoulos, Ioannis, Theo A J Van der Lee, Ronald P. de Vries, Sarah B. Ware, Igor V. Grigoriev, Churchill Alice C. L., Kuzniar, Arnold, Tu, Hank, van Ham, R.C.H., Cools, H. J. +367 morecore +1 more sourceThe role of plant defence proteins in fungal pathogenesis
Molecular Plant Pathology, 2007 SUMMARY It is becoming increasingly evident that a plant–pathogen interaction may be compared to an open warfare, whose major weapons are proteins synthesized by both organisms. These weapons were gradually developed in what must have been a multimillion‐year evolutionary game of ping‐pong.Ricardo B, Ferreira, Sara, Monteiro, Regina, Freitas, Cláudia N, Santos, Zhenjia, Chen, Luís M, Batista, João, Duarte, Alexandre, Borges, Artur R, Teixeira +8 moreopenaire +2 more sourcesPathogen‐Centric Activation of an Azoreductase‐Responsive Antibody‐Antibiotic Conjugate for the Targeted Eradication of MRSA
Advanced Science, EarlyView.A pathogen‐centric antibody‐antibiotic conjugate (AZO‐AAC) releases antibiotics via bacterial azoreductase, independent of host‐lysosomal function. This mechanism achieves nanomolar eradication of both planktonic and intracellular methicillin‐resistant Staphylococcus aureus (MRSA).Qi Cheng, Lianqi Liu, Chenghua Liu, Fei Xie, Jingwen Dong, Xiaoyu Qin, Shunxiang Huang, Xian Li, Xingyuan Kou, Hongbin Deng, Jiannan Feng, Wu Zhong, Dian Xiao, Xinbo Zhou +13 morewiley +1 more sourceMultiple avirulence paralogues in cereal powdery mildew fungi may contribute to parasite fitness and defeat of plant resistance
, 2006 Powdery mildews, obligate biotrophic fungal parasites on a wide range of important crops, can be controlled by plant resistance (R) genes, but these are rapidly overcome by parasite mutants evading recognition.Porritt, Oliver, Jones, Jonathan D. G., Porritt, O, Sacristan, S, Ridout, CJ, Ridout, Christopher J., Brown, James K. M., Skamnioti, Pari, Skamnioti, Paraskevi, Sacristán Benayas, Soledad, Brown, JK, Jones, JD +11 morecore +1 more sourceA structural and biochemical model of processive chitin synthesis [PDF]
, 2014 Chitin synthases (CHS) produce chitin, an essential component of the fungal cell wall. The molecular mechanism of processive chitin synthesis is not understood, limiting the discovery of new inhibitors of this enzyme class.Ferenbach, Andrew T., van Aalten, Daan M. F., Borodkin, Vladimir S., Dorfmueller, Helge Christian; id_orcid +3 morecore +1 more source
