Results 51 to 60 of about 346,800 (296)
Universal and unique features of kinesin motors: Insights from a comparison of fungal and animal conventional kinesins [PDF]
, 1999 Kinesins are microtubule motors that use the energy derived from the hydrolysis of ATP to move unidirectionally along microtubules, The founding member of this still growing superfamily is conventional kinesin, a dimeric motor that moves processively ...
Hackney D.D. +5 more
core +1 more source
Fungome: Annotating proteins implicated in fungal pathogenesis [PDF]
Bioinformation, 2010 Sequencing genomes of different pathogenic fungi produced plethora of genetic information. This "omics" data might be of great interest to probe strain diversity, identify virulence factors and complementary genes in other fungal species, and importantly in predicting the role of proteins specific to pathogenesis in humans.
Ranganath, Gudimella +3 more
openaire +2 more sources
The genome sequence and effector complement of the flax rust pathogen Melampsora lini [PDF]
, 2016 Rust fungi cause serious yield reductions on crops, including wheat, barley, soybean, coffee, and represent real threats to global food security. Of these fungi, the flax rust pathogen Melampsora lini has been developed most extensively over the past 80 ...
Anderson, Claire +9 more
core +1 more source
Protein engineering of fungal xylanase [PDF]
, 2021 Protein engineering technologies, such as directed evolution and DNA recombination, are often used to modify enzymes on a genetic level for the creation of useful industrial catalysts. Pre-treatment of paper pulps with xylanases have been shown to decrease the amounts of toxic chlorine dioxide used to bleach pulp.
openaire +1 more source
Fungal effector proteins: past, present and future [PDF]
Molecular Plant Pathology, 2009 SUMMARY The pioneering research of Harold Flor on flax and the flax rust fungus culminated in his gene‐for‐gene hypothesis. It took nearly 50 years before the first fungal avirulence ( Avr ) gene in support of his hypothesis was cloned.
de Wit, P.J.G.M. +3 more
openaire +3 more sources
Roles of Rack1 Proteins in Fungal Pathogenesis [PDF]
BioMed Research International, 2016 Pathogenic fungi cause diseases on various organisms. Despite their differences in life cycles, fungal pathogens use well-conserved proteins and pathways to regulate developmental and infection processes. In this review, we focus on Rack1, a multifaceted scaffolding protein involved in various biological processes. Rack1 is well conserved in eukaryotes
Xue Zhang, Rashmi Jain, Guotian Li
openaire +2 more sources
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
Deciphering effector function in the Magnaporthe oryzae rice interaction [PDF]
, 2011 Effectors are central to virulence in all pathogenic organisms and to their adaptation to specific hosts. However, the role and molecular function of fungal effector proteins is largely unknown. A better understanding of fungal effectors is necessary for
Cesari, C. +6 more
core
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
NcPred for accurate nuclear protein prediction using n-mer statistics with various classification algorithms [PDF]
, 2011 Prediction of nuclear proteins is one of the major challenges in genome annotation. A method, NcPred is described, for predicting nuclear proteins with higher accuracy exploiting n-mer statistics with different classification algorithms namely ...
A. Ganesh +14 more
core +3 more sources