Results 221 to 230 of about 1,109,640 (363)

Molecular Insights into Fungal Glycosylphosphatidylinositol Transamidase Complex

open access: yesAdvanced Science, EarlyView.
The glycosylphosphatidylinositol (GPI) biosynthesis pathway is critical for antifungal drug development. This study reports three cryo‐electron microscopy structures of fungal GPI transamidase (GPIT), captured in two substrate‐bound states and a novel dimeric assembly.
Zhengkang Hua   +12 more
wiley   +1 more source

Shifu‐Inspired Fungal Paper Yarns

open access: yesAdvanced Science, EarlyView.
Fungal chitin‐β‐glucan sheets, processed using Shifu techniques, yield yarns with tunable strength and mechanical properties matching or surpassing cotton and viscose. Chemical modification and hybridization routes enable further property control.
Anne Zhao   +3 more
wiley   +1 more source

Intestinal fungal signatures and their impact on immune checkpoint inhibitor efficacy: a multi-cohort meta-analysis. [PDF]

open access: yesNPJ Biofilms Microbiomes
Zhang L   +10 more
europepmc   +1 more source

Dual Disruption of the Immune Cytokine Spätzle Facilitates Fungal Infection of Diverse Insect Hosts

open access: yesAdvanced Science, EarlyView.
The Toll pathway is essential for insect defense against fungal pathogens. This works reports that fungal parasites employ two divergent virulent effectors to target the Toll receptor ligand Spätzle: a metalloprotease degrading it and a hairpin‐like effector hijacking it to block signal transduction. This dual strategy enables the fungus to kill a wide
Shuangxiu Song   +7 more
wiley   +1 more source

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