Results 21 to 30 of about 31,243 (257)

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source

The Mechanisms of Developing Fungicide Resistance in Fusarium graminearum Causing Fusarium Head Blight and Fungicide Resistance Management

Pathogens
Fusarium head blight (FHB), primarily caused by Fusarium graminearum, is one of the economically significant diseases in small grains. FHB causes severe damage to wheat production and grain quality.
Malini Anudya Jayawardana, Wannakuwattewaduge Gerard Dilantha Fernando   +1 more
doaj   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

Effects on yield and nutritional value of corn silage from corn treated with foliar fungicide and microbial inoculant on ensiling [PDF]

Arquivo Brasileiro de Medicina Veterinária e Zootecnia
The aim of this study was to evaluate the yield, the morphometric characteristics, and the nutritional value of corn with use of foliar fungicide associated with inoculant on ensiling on the chemical-fermentative characteristics of silage.
M. Neumann, E.H. Horst, E.L.C. Pereira, P.V.P. Cesar, A.M. Souza, E. Baldissera, V. Kalinovski, D.R.S. Pinto, L. Costa, B.J. Venancio   +9 more
doaj   +1 more source

The Evolution of Fungicide Resistance

, 2015
Fungicides are widely used in developed agricultural systems to control disease and safeguard crop yield and quality. Over time, however, resistance to many of the most effective fungicides has emerged and spread in pathogen populations, compromising disease control. This review describes the development of resistance using case histories based on four
Lucas, J. A., Hawkins, N. J., Fraaije, B. A.   +2 more
openaire   +2 more sources

The Emergence of Resistance to Fungicides

PLoS ONE, 2014
Many studies exist about the selection phase of fungicide resistance evolution, where a resistant strain is present in a pathogen population and is differentially selected for by the application of fungicides. The emergence phase of the evolution of fungicide resistance--where the resistant strain is not present in the population and has to arise ...
Hobbelen, P. H. F., Paveley, N. D., Van Den Bosch, F.   +2 more
openaire   +4 more sources

A Systematic Study of GelMA‐Carbopol Bioinks for High‐Fidelity Extrusion 3D Bioprinting at Physiological Temperatures

Advanced Healthcare Materials, EarlyView.
Gonzalez Martinez and collaborators develop a strategy to formulate high performance GelMA‐based bioinks with low solids contents. The resulting bioinks enable 3D bioprinting at 37 °C of high‐fidelity structures with tunable mechanical properties that support high cell viability and function.
David A. González‐Martínez, Aidee V. Arizpe Tafoya, Eduardo González‐Martínez, Mabel Barreiro Carpio, Laura Daniela Serrano Andrade, Christopher T. N. Chow, Mohammadhossein Dabaghi, Jeremy A. Hirota, Jose M. Moran‐Mirabal   +8 more
wiley   +1 more source

Environmental behavior assessment Thiophanate methyl in the soil using different mathematical models

Kufa Journal for Agricultural Sciences
One of the most common fungicides, Thiophanate-methyl (TM), has been extensively used to prevent fusarium wilt disease. Understanding the kinetic behavior of the TM-fungicide in the greenhouse soil was aimed at the current research.
Hawraa Mehdi Saleh, Alaa Hassan A Al-Farttoosy   +1 more
doaj   +1 more source

Fungicide models are key components of multiple modelling approaches for decision-making in crop protection

Phytopathologia Mediterranea, 2018
Decision-making for integrated pest management (IPM) in crops requires the assessment of multiple risk factors. Plant disease models have been used to predict disease risk and support decisions about whether and when to protect crops based on ...
Tito CAFFI, Vittorio ROSSI
doaj   +1 more source

Effectiveness of Mancozeb and Benalaxyl Against Purple Blotch Disease Caused by Alternaria porri Howard (Dothideomycetes: Pleosporaceae) In Shallot (Allium ascalonicum L.)

JTPP: Journal of Tropical Plant Protection, 2022
The common control of purple blotch disease of shallot cause by Alternaria porri is using fungicide. Application of mancozeb and benalaxyl was reported effectively suppress the intensity of purple blotch disease.
Liana Juvita, Anton Muhibuddin
doaj   +1 more source