Results 51 to 60 of about 2,362,586 (281)

The use of mathematical models to guide fungicide resistance management decisions

, 2015
Historically, models have had little influence on decision-making in fungicide resistance management. The reasons are found in the level of abstraction of these models making it difficult for stakeholders to interpret them and inadequate connection ...
Oliver, R., Richard Oliver, Paveley, N., Oliver, Richard, Fraaije, B. A., Frank van den Bosch, Femke van den Berg, Van Den Berg, F., Bart Fraaije, Van Den Bosch, F., Fraaije, B., Neil Paveley, Fraaije, Bart, Van Den Berg, Femke, Vandenbosch, Frank   +14 more
core   +1 more source

Extracellular vesicle lipidomics liquid biopsy reveals systemic and tumor microenvironment metabolic reprogramming in ovarian cancer

Molecular Oncology, EarlyView.
Extracellular vesicle (EV) lipidomic profiling of plasma and ascites from patients with high‐grade serous ovarian cancer and of ovarian cancer cell lines reveals enrichment of triglycerides (TGs), diacylglycerols (DGs), phosphatidylcholine (PCs), sphingomyelins (SMs), reflecting tumor metabolic reprogramming.
Shikha Rani, Dominic Guanzon, Andrew Lai, Katherin Scholz‐Romero, Sarah Reed, Edita Ritmejeryte, Rohan Lourie, Naven Chetty, Kaltin Ferguson, Carlos Salomon   +9 more
wiley   +1 more source

Nanopore sequencing and hybrid assembly: unraveling the genomic landscape of dollar spot with enhanced annotation and drug resistance profiling

Frontiers in Fungal Biology
The increasing multi-drug resistance observed in the turfgrass pathogen Clarireedia spp. has emerged as a critical issue. Understanding the mechanisms underlying fungicide resistance is crucial to address this challenge. This study focuses on comparing a
Xiaojing Shi, Shu Zhao, John G. Gibbons, Geunhwa Jung   +3 more
doaj   +1 more source

Engineering IL‐4 resistant proinflammatory human myeloid cells for cancer immunotherapy

Molecular Oncology, EarlyView.
We developed a scalable workflow to generate proinflammatory human myeloid cells. CRISPR/Cas9‐edited CD34+ hematopoietic stem and progenitor cells were expanded and differentiated with M‐CSF. Deletion of STAT6 or STAT6/NFKB1 enhanced macrophage proinflammatory gene expression and cytokine secretion in the presence of IL‐4 while maintaining antibody ...
Theresa Barberi, Alan D. Friedman
wiley   +1 more source

Evolution‐guided yeast complementation reveals functional differences in human PSPH variants

FEBS Open Bio, EarlyView.
Ancient genomes can help guide which human genetic variants are tested experimentally. This study applies that idea to PSPH, a gene involved in serine biosynthesis, and uses high‐throughput yeast complementation to compare variant function. The findings reveal measurable differences among selected alleles and illustrate the value of evolution‐guided ...
Mauricio Campa‐Álvarez, Diana Ascencio, Miguel Vallebueno‐Estrada, Eduardo González‐Orozco, Christian Eduardo Martínez‐Guerrero, Rafael Montiel, Alexander DeLuna   +6 more
wiley   +1 more source

Induced Expression of CYP51a and HK1 Genes Associated with Penconazole and Fludioxonil Resistance in the Potato Pathogen Fusarium oxysporum

Microorganisms, 2023
Preventing antifungal resistance development and identifying pathogens with high, medium, and low risk of resistance development to a particular fungicide or fungicide class is crucial in the fight against phytopathogens. We characterized the sensitivity
Yaw A. Akosah, Zarina S. Kostennikova, Marat T. Lutfullin, Guzel F. Lutfullina, Daniel M. Afordoanyi, Semyon G. Vologin, Ayslu M. Mardanova   +6 more
doaj   +1 more source

Fungi Resistance to Multissite Fungicides

Journal of Agricultural Science, 2021
Multisite fungicides have been used for many years in fruit and vegetable crops worldwide. Cases of the fungi resistance development to these fungicides have been rare. From the 2002 season onwards, with the outbreak of Asian soybean rust in Brazil, caused by Phakopsora pachyrhizi, site-specific fungicides became the main weapon for its control.
Erlei Melo Reis, Wanderlei Dias Guerra, Andrea Camargo Reis, Mateus Zanatta, Marcelo Carmona, Francisco Sautura   +5 more
openaire   +2 more sources

Fungicide Resistance and Misinformation: A Game Theoretic Approach [PDF]

, 2020
Fungicide resistance developed by pathogens that grapes are susceptible to is problematic for the industry today. We provide further insight into the strategic behavior of grape growers when their choices of fungicide levels generate a negative ...
Pardini, Chelsea A., Espinola-Arredondo, Ana   +1 more
core   +1 more source

Avidin is evolutionarily conserved in fish but dispensable for development and resistance against Streptococcus agalactiae in zebrafish

FEBS Open Bio, EarlyView.
The presence of biotin‐binding avidin proteins in fish and their biological significance are poorly characterized. We cataloged fish avidins and demonstrate that they are widely present and evolutionarily conserved. We created avd knockout zebrafish and show that zebavidin is dispensable for development and that resistance of avd knockout embryos in ...
Anni K. Saralahti, Markus J. T. Ojanen, Mataleena Parikka, Otto Kauko, Mika Rämet, Vesa P. Hytönen   +5 more
wiley   +1 more source

Rise and Fall of Phytophthora infestans Resistance to Non-Specific Fungicide in Experimental Populations

Journal of Fungi
Background: Fungicide resistance is one of the major factors threatening social and ecological sustainability. Many issues associated with the evolutionary processes and mechanisms of fungicide resistance in pathogens remain poorly understood, and better
Shao-Bin Fan, Meng Xie, Zu-Lei Xiang, Tong-Xin Xu, Wen-Jing Wang, Zong-Hua Wang, Hong-Li Hu, Li-Xia Chen, Li Tang, Jia-Sui Zhan, Li-Na Yang   +10 more
doaj   +1 more source