Results 31 to 40 of about 7,534 (264)

Mechanical and Electrical Phenotype of hiPSC‐Cardiomyocytes on Fibronectin‐Based Hydrogels

Advanced Healthcare Materials, EarlyView.
We introduce fibronectin‐based PEG hydrogels with controlled rigidity to enable the culture of iPSC‐derived cardiomyocytes. These substrates offer an alternative to the current culture of these cells on fibronectin‐coated glass, providing enhanced structural and functional behavior. The system provides a more physiologically relevant platform to assess
Ana Da Silva Costa, Lineta Stonkute, Sara Trujillo, Mariana Azevedo Gonzalez Oliva, Francis Burton, Matthew J. Dalby, Oana Dobre, Godfrey Smith, Manuel Salmeron‐Sanchez   +8 more
wiley   +1 more source

Biodiesel Industrial Waste based onJatropha curcasas a Fungicide to ControlFusarium oxysporumandAlternaria solani

E3S Web of Conferences, 2023
Fusarium oxysporum(Schlecht. emend. Snyder & Hansen.) is the most devastating pathogens causing wilt disease on the tomatoes (Solanum lycopersicumL.) plant, whereasAlternaria solani(Sorauer), is a pathogen that caused early blight on potatoes (Solanum tuberosumL.)Jatropha curcasL. is a biodiesel material known as a potential fungicide.
Henik Sukorini, Dyah Erni Widyastuti, Dini Kurniawati, Sawita Suwannarat, Maizirwan Mel, Roy Hendroko Setyobudi   +5 more
openaire   +2 more sources

Targeting Post‐Irradiation Thyroid Dysfunction: Electrospun Scaffolds As A Dual‐Action Approach for Antioxidant and Immune Modulation

Advanced Healthcare Materials, EarlyView.
Radiation‐induced hypothyroidism follows head and neck radiotherapy due to oxidative stress and inflammation. Electrospun polycaprolactone scaffolds containing adenosine have potential to modulate thyroid repair. Scaffolds enhance thyrocyte proliferation, antioxidant enzymes glutathione peroxidase and catalase, reduce senescence and apoptosis markers ...
Maria Heim, Ella‐Louise Handley, Daniel Grant, Lizi M. Hegarty, Elaine Emmerson, Anthony Callanan   +5 more
wiley   +1 more source

Protective role of glutathione in oxidative stress caused by cadmium and copper

European Psychiatry, 2022
Introduction Cadmium is defined as one of the leading toxic industrial pollutants (Valko i sar., 2005). Although some products containing cadmium can be recycled, much of the pollution with this metal is the result of inadequate disposal and ...
J. Jovanovic Mirkovic, G. Kocic, Z. Jurinjak, C. Alexopoulos   +3 more
doaj   +1 more source

Invention and Industrialization of New Optically Active Triazolyl Plant Growth Regulator and Fungicide.

NIPPON KAGAKU KAISHI, 1994
著者らが先に見出した殺菌剤ブチオオートの構造活性相関や作用機作研究の結果を活用した分子設計により,強い植物生畏調節活性と殺菌活性を餅せ持つ新規な2-(トリアゾリル)アリルアルコール系化合物を得た.本化合物には幾何異性体と光学異性体が存在する。E異性体の活性はZ異性体に比して大幅に向上すること,また,檀物生長鯛節活性はS体に,殺菌活性はR体に集中していることを明らかにし,二つの薬効の分離に成功した,前者はジべレリンの,後者はエルゴステロールの生合成を選択的に阻害する。製造法では,E/Z異性化技術と分離技術を組み合わせた異性化晶析法を開発し,E体を選択的に合成する簡便な工業的製造法を確立した。また,新規な不斉修飾剤であるアミノアルコールと水素化アルミニウムリチウムを用いる ...
Shizuya TANAKA, Yuji FUNAKI, Gohfu SUZUKAMO, Yukio YONEYOSHI, Kazuhiro TADA   +4 more
openaire   +2 more sources

Industrial treatment of soybean seeds subjected to high volumes of fungicides, insecticides, biostimulants and micronutrients during storage

Australian Journal of Crop Science, 2022
The objective of this study was to examine the performance of soybean seeds at different storage periods as well as their physiological quality after the application of spray mixtures of insecticides, fungicides, polymers, micronutrients and biostimulants. The experiment was laid out in a completely randomized design with four replicates.
Renata Cristiane Pereira, Breno Gabriel da Silva, Alessandro Lucca Braccini, Silas Maciel de Oliveira, Carla Coppo, Géssica Gaboardi De Bastiane, Murilo Fuentes Pelloso, Yana Miranda Borges   +7 more
openaire   +1 more source

A 3D Bioprinted Spheroid‐Laden dECM‐Enriched Osteosarcoma Model for Enhanced Drug Testing and Therapeutic Discovery

Advanced Healthcare Materials, EarlyView.
A 3D biomimetic OS model was developed by bioprinting an OS‐cell‐derived dECM‐enriched bioink with OS spheroids incorporated. The model showed upregulation of known OS prognostic markers and increased resistance to doxorubicin, compared to 2D cultures and scaffold‐free spheroids, making this a more clinically relevant platform for drug discovery ...
Margarida F. Domingues, Maria Catarina Carreira, Mafalda S. Santos, Daniela Pacheco, Frederico Castelo Ferreira, Paola Sanjuan‐Alberte, João Carlos Silva   +6 more
wiley   +1 more source

Nano-scale defenders tackling sweet cherry (Prunus avium) fungal threats with eco-friendly zinc oxide nanoparticles

Plant Nano Biology
Green nanotechnology holds significant potential for use in agriculture due to its antifungal properties, ability to control fungal diseases, and reduce the reliance on chemical fungicides. Prunus avium (sweet cherry) is highly valued for its nutritional
Muhammad Aamir Manzoor, Xunju Liu, Yan Xu, Irfan Ali Sabir, Iftikhar Hussain Shah, Ghulam Abbas Ashraf, Muhammad Azam, Shazma Gulzar, Songtao Jiu, Caixi Zhang   +9 more
doaj   +1 more source

Redefining Therapies for Drug‐Resistant Tuberculosis: Synergistic Effects of Antimicrobial Peptides, Nanotechnology, and Computational Design

Advanced Healthcare Materials, EarlyView.
Antimicrobial peptide (AMP)‐loaded nanocarriers provide a multifunctional strategy to combat drug‐resistant Mycobacterium tuberculosis. By enhancing intracellular delivery, bypassing efflux pumps, and disrupting bacterial membranes, this platform restores phagolysosome fusion and macrophage function.
Christian S. Carnero Canales, Jessica Ingrid Marquez Cazorla, Renzo Marianito Marquez Cazorla, Aline Martins dos Santos, Jonatas Lobato Duarte, Letícia Oliveira Catarin Nunes, Túlio Custódio Reis, Lara Cerazi Salvador, Norival Alves Santos‐Filho, Rafael Miguel Sábio, Hélder A. Santos, Fernando Rogério Pavan   +11 more
wiley   +1 more source

Skin‐Interfaced Therapeutic Patches for Wound Fluid Management and Transdermal Drug Delivery

Advanced Healthcare Materials, EarlyView.
This study presents an integrated skin‐interfaced device combining microfluidics, hydrogel film technology, flexible electronics, and iontophoresis‐based transdermal delivery of PDRN to enhance wound healing. The device effectively manages wound fluid, maintains optimal moisture, and non‐invasively delivers therapeutic drugs.
Dongjun Han, Donghyun Kim, Haram Lee, Dong‐Wook Park, Sung Soo Kwak, Joohee Kim   +5 more
wiley   +1 more source