Results 31 to 40 of about 7,902 (264)

Enhancing Enzyme Activity With Mutation Combinations Guided by Few‐Shot Learning and Causal Inference

Angewandte Chemie, EarlyView.
We present an integrated workflow that predicts activity‐enhancing mutation combinations from minimal experimental data. By proposing in vivo unit yield (yield/expression) as a surrogate for kcat/Km through causal inference, and visualizing local activity landscape, it effectively guides product yield improvement. ABSTRACT Designing enzyme sequences to
Lin Guo, Xiaoguang Yan, Yali Lu, Shengxin Nie, Mingyue Ge, Yukun Li, Weiguo Li, Xiaochun Zhang, Dongmei Liang, Yihan Zhao, Hongxiao Tan, Xiling Chen, Shilong Fan, Yefeng Tang, Jianjun Qiao, Boxue Tian   +15 more
wiley   +2 more sources

Phenolic-Rich Extracts from Circular Economy: Chemical Profile and Activity against Filamentous Fungi and Dermatophytes

Molecules, 2023
Fungal infections represent a relevant issue in agri-food and biomedical fields because they could compromise quality of food and humans’ health. Natural extracts represent a safe alternative to synthetic fungicides and in the green chemistry and ...
Andrea Lombardi, Margherita Campo, Pamela Vignolini, Marco Papalini, Mirco Pizzetti, Roberta Bernini   +5 more
doaj   +1 more source

Packed for Ossification: High‐Density Bioprinting of hPDC Spheroids in HAMA Toward Endochondral Ossification

Advanced Healthcare Materials, EarlyView.
Human periosteum‐derived cell spheroids bioprinted at high density within a hyaluronic acid matrix promote fusion and hypertrophic cartilage formation in vitro. Early encapsulation enhances spheroid interaction and matrix maturation, generating scalable cartilage templates intended for endochondral bone regeneration.
Ane Albillos Sanchez, Maria Paula Marks, Paula Casademunt, Adrián Seijas‐Gamardo, Ioannis Papantoniou, Lorenzo Moroni, Carlos Mota   +6 more
wiley   +1 more source

Enhanced Early Detection and Precision Monitoring of Rubber Tree Powdery Mildew Pathogen Erysiphe quercicola Using Quantitative PCR and Droplet Digital PCR

Journal of Fungi
Rubber trees are crucial to the global industrial economy, but they are facing the threat of powdery mildew caused by Erysiphe quercicola. Effective management of this disease depends on early detection.
Xiaoyu Liang, Deyu Feng, Mengyuan Xiong, Shaoyao Zhou, Lifeng Wang, Shanying Zhang, Meng Wang, Yu Zhang   +7 more
doaj   +1 more source

Biodiesel Industrial Waste based onJatropha curcasas a Fungicide to ControlFusarium oxysporumandAlternaria solani

E3S Web of Conferences, 2023
Fusarium oxysporum(Schlecht. emend. Snyder & Hansen.) is the most devastating pathogens causing wilt disease on the tomatoes (Solanum lycopersicumL.) plant, whereasAlternaria solani(Sorauer), is a pathogen that caused early blight on potatoes (Solanum tuberosumL.)Jatropha curcasL. is a biodiesel material known as a potential fungicide.
Henik Sukorini, Dyah Erni Widyastuti, Dini Kurniawati, Sawita Suwannarat, Maizirwan Mel, Roy Hendroko Setyobudi   +5 more
openaire   +2 more sources

A Systematic Study of GelMA‐Carbopol Bioinks for High‐Fidelity Extrusion 3D Bioprinting at Physiological Temperatures

Advanced Healthcare Materials, EarlyView.
Gonzalez Martinez and collaborators develop a strategy to formulate high performance GelMA‐based bioinks with low solids contents. The resulting bioinks enable 3D bioprinting at 37 °C of high‐fidelity structures with tunable mechanical properties that support high cell viability and function.
David A. González‐Martínez, Aidee V. Arizpe Tafoya, Eduardo González‐Martínez, Mabel Barreiro Carpio, Laura Daniela Serrano Andrade, Christopher T. N. Chow, Mohammadhossein Dabaghi, Jeremy A. Hirota, Jose M. Moran‐Mirabal   +8 more
wiley   +1 more source

Copper stress affect seed germination and seedling establishment of Schinus terebinthifolia Raddi

Hoehnea, 2020
Pollution by the discharge of copper in the environment due to anthropogenic, industrial, and automobile activities is an environmental problem. Copper is also widely used in different forms as fertilizers and fungicides.
Matheus Casarini Siqueira, Armando Reis Tavares, José Marcos Barbosa, Nelson Augusto dos Santos Junior   +3 more
doaj   +1 more source

Invention and Industrialization of New Optically Active Triazolyl Plant Growth Regulator and Fungicide.

NIPPON KAGAKU KAISHI, 1994
著者らが先に見出した殺菌剤ブチオオートの構造活性相関や作用機作研究の結果を活用した分子設計により,強い植物生畏調節活性と殺菌活性を餅せ持つ新規な2-(トリアゾリル)アリルアルコール系化合物を得た.本化合物には幾何異性体と光学異性体が存在する。E異性体の活性はZ異性体に比して大幅に向上すること,また,檀物生長鯛節活性はS体に,殺菌活性はR体に集中していることを明らかにし,二つの薬効の分離に成功した,前者はジべレリンの,後者はエルゴステロールの生合成を選択的に阻害する。製造法では,E/Z異性化技術と分離技術を組み合わせた異性化晶析法を開発し,E体を選択的に合成する簡便な工業的製造法を確立した。また,新規な不斉修飾剤であるアミノアルコールと水素化アルミニウムリチウムを用いる ...
Shizuya TANAKA, Yuji FUNAKI, Gohfu SUZUKAMO, Yukio YONEYOSHI, Kazuhiro TADA   +4 more
openaire   +2 more sources

Fungicide Registration and a Small Niche Market: A Case History of Hymexazol Seed Treatment and the U.S. Sugar Beet Industry [PDF]

Plant Disease, 2007
The United States ranks among the top four sugar producers worldwide, and sugar beet (Beta vulgaris L.) plays a major role in the sweetener industry. Sugar beet was planted on approximately 553,100 ha (1.37 million acres) in 2006 (33). The greatest volume of production occurs in the Red River Valley (RRV) of Minnesota and North Dakota and in southern ...
Harveson, R. M., Windels, C. E., Smith, J. A., Brantner, J. R., Cattanach, A. W., Giles, J. F., Hubbell, L., Cattanach, N. R.   +7 more
openaire   +2 more sources

Atomic Layer Deposition Processes: Versatile Platforms for Engineering ZnO‐Chitosan Biointerfaces

Advanced Healthcare Materials, EarlyView.
Vapour phase metalation (VPM), multiplied pulsed vapour phase infiltration (MPI), and O2 plasma‑enhanced atomic layer deposition (PEALD) tailor Zn–chitosan (Zn‑CS) films. PEALD improves wettability and biocompatibility. MPI enhances semiconductor behavior. Antiseptic selectivity: VPM → E. coli; MPI → H. pylori.
Mabel Moreno, Anjana Devi, David Zanders, Miryam Arredondo, Davide Mariotti, Ruairi McGlynn, Sindy Devis, Simón Guerrero, Eglantina Benavente, Matias Alegría, Yusser Olguin, Lorena Lobos‐Gonzalez, Kevin Guzmán, Elizabeth Rivas‐Yañez, Paula Solar, Valentin Cepus, Michael Krause, Luis Velásquez   +17 more
wiley   +1 more source