Results 231 to 240 of about 541,445 (355)

Machine Learning‐Enhanced Clinical Decision Support for Diagnosing Sinusitis With Nasal Endoscopy

open access: yesInternational Forum of Allergy &Rhinology, EarlyView.
ABSTRACT Background Sinusitis is a prevalent disease for which nasal endoscopy (NE) is an optimal diagnostic modality. However, NE accuracy is limited by inter‐operator variability in landmark identification and localization of mucus that is necessary for sinusitis diagnosis. We sought to develop a novel multi‐class machine learning (ML) framework that
Dipesh Gyawali   +12 more
wiley   +1 more source

Cross-country multi-modal evidence links Aspergillus to biliary atresia. [PDF]

open access: yesGut Pathog
Huang SW   +5 more
europepmc   +1 more source

Disruption of ovarian function and induction of apoptosis in female mice by Brefeldin A: Mechanistic insights into reproductive toxicity

open access: yesAnimal Models and Experimental Medicine, EarlyView.
Brefeldin A (BFA) significantly inhibits oocyte release and induces apoptosis in ovarian granulosa cells by disrupting follicular development. It downregulates proliferation‐associated genes, reduces SIRT1/SIRT6 proteins, and upregulates cell cycle inhibitors P21 and P16. Additionally, BFA impairs estrogen synthesis and affects ovarian function through
Yao Jiang   +8 more
wiley   +1 more source

Supramolecular Carbohydrate Assemblies with Tunable Glycan Surfaces

open access: yesAngewandte Chemie, EarlyView.
Synthetic cellulose‐based oligomers assemble into supramolecular nanomaterials with a molecularly controlled, dense presentation of carbohydrates on their surfaces, serving as biological cues. Abstract The self‐assembly of molecular building blocks into ordered supramolecular structures enables the creation of nanomaterials that can display ligands on ...
Nives Hribernik   +7 more
wiley   +2 more sources

An arbuscular mycorrhiza from the 407-million-year-old Windyfield Chert identified through advanced fluorescence and Raman imaging. [PDF]

open access: yesNew Phytol
Strullu-Derrien C   +7 more
europepmc   +1 more source

Surface‐Coated Inorganic Nanomaterials for Drug Delivery: Chemical Design, Biomedical Applications, and Mechanistic Insights

open access: yesAdvanced NanoBiomed Research, EarlyView.
This review explores how surface‐coated inorganic nanomaterials are chemically engineered for advanced drug delivery. It highlights design principles, coating strategies, and biomedical applications, emphasizing how surface chemistry governs biocompatibility, targeting, and controlled release.
Hossein Daneshgar   +4 more
wiley   +1 more source

Fluorescent Probes Derived from the Polyene Class of Antifungal Drugs Reveal Distinct Localization Patterns and Resistance‐Associated Vacuolar Sequestration in Candida Species

open access: yesAngewandte Chemie, EarlyView.
Fluorescent probes derived from all three clinically used polyene antifungals (amphotericin B, nystatin, and natamycin) enabled direct visualization of distribution in yeast cells of various Candida species. While retaining the ergosterol‐dependent mode of action of their parent drugs, the probes revealed distinct, structure‐specific localization ...
Melissa Shbeta   +6 more
wiley   +2 more sources

New records of powdery mildew fungi on stone fruits from India. [PDF]

open access: yesSci Rep
Surma S   +7 more
europepmc   +1 more source

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