Results 291 to 300 of about 394,510 (337)

Development of Xanthyletin-Loaded Nanoparticles for the Control of <i>Leucoagaricus gongylophorus</i>. [PDF]

open access: yesMolecules
Cazal CM   +8 more
europepmc   +1 more source

Boosting Antibiotic Efficacy of Azole Drugs against Methicillin‐Resistant Staphylococcus Aureus by Coordination to Rhenium Carbonyl Complexes

open access: yesChemBioChem, EarlyView.
Coordination of antifungal azoles to rhenium di‐ and tricarbonyl complexes results in compounds with enhanced antimicrobial efficacy—up to 32‐fold minimum inhibitory concentration improvement—against methicillin‐sensitive and methicillin‐resistant Staphylococcus aureus over parent azoles.
Kevin Schindler   +12 more
wiley   +1 more source

Beyond Histones: Unveiling the Functional Roles of Protein Acetylation in Prokaryotes and Eukaryotes

open access: yesCell Biology International, EarlyView.
ABSTRACT Lysine acetylation plays a crucial role in cellular processes and is found across various evolutionary organisms. Recent advancements in proteomic techniques revealed the presence of acetylation in thousands of non‐histone proteins. Here, we conducted extensive meta‐analysis of 48 acetylomes spanning diverse organisms, including archaea ...
Bruno Sousa Bonifácio   +6 more
wiley   +1 more source

Molecular basis for the biosynthesis of the siderophore coprogen in the cheese-ripening fungus Penicillium roqueforti. [PDF]

open access: yesBiol Res
González K   +8 more
europepmc   +1 more source

Insights into the Mechanism of a Vanadium Bromoperoxidase from the Marine Macro‐Algae Corallina pilulifera for Biocatalytic Halogenation

open access: yesChemCatChem, EarlyView.
A study of crystallographic complexes obtained from vanadium haloperoxidase enzymes can determine key amino acids, leucine, and phenylalanine, that change their structural orientation to allow either chloride or bromide to bind to the enzymes active site, thereby determining halide specificity.
Daniel E. Mitchell   +3 more
wiley   +1 more source

Effects of defined organic layers on the fluorescence lifetime of plastic materials. [PDF]

open access: yesAnal Bioanal Chem
Leiter N   +12 more
europepmc   +1 more source

Identification of Pyrrolizilactone Biosynthetic Gene Cluster with Unique Short‐Chain Dehydrogenase Gene for 3‐Methylproline Formation

open access: yesChemistryEurope, EarlyView.
A standalone enzyme, derived from the reductase domain of a polyketide synthase‐nonribosomal peptide synthetase hybrid enzyme, is identified as a pyrroline carboxylate reductase. This enzyme is involved in the biosynthesis of 3‐methylproline, an amino acid building block of a unique tricyclic pyrrolizidinone structure of a fungal metabolite ...
Naoki Kato   +6 more
wiley   +1 more source

Novel Synthesis of the Antifungal Cyclic Lipopeptide Iturin A and Its Fluorinated Analog for Structure‐Activity Relationship Studies

open access: yesChemistry – A European Journal, EarlyView.
Iturin A is an antifungal lipopeptide with a wide range of applications. In this study, we present a novel synthesis of iturin A via enantiomeric synthesis of the β‐amino fatty acid and on‐resin cyclization. We also obtained the (S)‐epimer of iturin A, showing a dramatic loss of bioactivity, and a monofluorinated analog, which retained the bioactivity ...
Periklis Karamanis   +6 more
wiley   +1 more source

A fourfold pathogen reference ontology suite. [PDF]

open access: yesJ Biomed Semantics
Beverley J   +10 more
europepmc   +1 more source

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