Results 51 to 60 of about 1,473 (162)
This study demonstrated that the pathogen responsible for diarrhoea in a cynomolgus monkey was identified as Proteus mirabilis (P. mirabilis) through methods including bacterial isolation and culture, morphological examination, biochemical profiling, 16S rRNA sequencing, analysis of key virulence genes and bacterial artificial infection tests.
Heling Li +6 more
wiley +1 more source
Mutations in the riboflavin biosynthesis pathway confer resistance to furazolidone and abolish the synergistic interaction between furazolidone and vancomycin in Escherichia coli. [PDF]
The combined application of furazolidone and vancomycin has previously been shown to be synergistic against Gram-negative pathogens, with great therapeutic promise.
Wykes H, Rakonjac J, Le VVH
core +1 more source
ABSTRACT Background Management of refractory Helicobacter pylori (H. pylori) infection remains challenging due to increasing antibiotic resistance and limited effective rescue options. Minocycline and furazolidone retain low resistance rates, while potassium‐competitive acid blockers (P‐CABs) provide potent and sustained acid suppression.
Ji‐Yan Li +10 more
wiley +1 more source
Metabolism of Furazolidone in Swine
SummaryOrally administered furazolidone is largely absorbed from the digestive tract by swine and excreted in the form of a large number of metabolic end products. Excretory half-times of products structurally related to furazolidone appear to be 30 min or less.
D M, Tennent, W H, Ray
openaire +2 more sources
Furazolidone induces the activity of microsomal enzymes that metabolize furazolidone in chickens [PDF]
The nitrofuran antibacterial agent furazolidone (FZ) is still used in veterinary medicine in some countries in the Middle and Far East. The present study aimed to show the effect of FZ on the activity of microsomal enzymes that metabolize FZ, and to identify the enzyme that contributes to FZ metabolism in chickens.
Sasaki, Nobuo +5 more
openaire +2 more sources
Background and aim Despite the increasing rates of antibiotic resistance, furazolidone-based regimens have demonstrated promise in Helicobacter pylori eradication. Therefore, this study aims to evaluate the comparative efficacy and safety of tetracycline
Jinliang Xie +8 more
doaj +1 more source
Pathogenic Vibrio species isolated from aquaculture environments in low‐ and middle‐income countries exhibit elevated antimicrobial resistance and multiple virulence traits. These findings highlight significant risks to fish health and food safety, underscoring the need for strengthened antimicrobial stewardship, robust biosecurity measures and ...
Asiphe Hobe +5 more
wiley +1 more source
BQT remains the most effective, safe, and practical regimen for H. pylori eradication, ensuring high cure rates across diverse resistance patterns and clinical settings. ABSTRACT Background Classic bismuth quadruple therapy (BQT)—the combination of a proton pump inhibitor, bismuth, tetracycline, and metronidazole—is a standard regimen for treating ...
Javier P. Gisbert +2 more
wiley +1 more source
This study elucidates pesticide docking onto proteins encoded by differentially expressed genes, revealing interaction networks involving chemicals, genes, proteins, drugs and diseases. It highlights structural insights, regulatory pathways and potential therapeutic or environmental implications, providing a comprehensive understanding of the ...
Jyoti Kant Choudhari +4 more
wiley +1 more source
Formulation and Advantages of Furazolidone in Spray Dried and Liposomal Drug Delivery Systems [PDF]
The current study has focused on the local delivery of furazolidone to the gut with the aim of generating alternative approaches for the treatment of Helicobacter pylori (H. pylori). Furazolidone has proven antibacterial activity against H. pylori, which
Alam, Muhammad Irfan
core +4 more sources

