Rifabutin Cross-resistance and Associated rpoB Mutations in Rifampicin-resistant Mycobacterium tuberculosis Complex Isolates [PDF]
Thoracic Research and PracticeOBJECTIVE: This study aimed to phenotypically evaluate rifabutin susceptibility in rifampicin-resistant Mycobacterium tuberculosis complex isolates and to identify, through DNA sequence analysis of the rifampicin resistance-determining region (RRDR ...
Nalan Sürücüoğlu +2 more
doaj +2 more sources
Visually significant corneal deposits associated with rifabutin therapy for Bartonella henselae [PDF]
American Journal of Ophthalmology Case ReportsPurpose: To report the clinical and histopathological features of a case of visually significant corneal deposits due to rifabutin therapy used to treat Bartonella henselae.
Ailin Song +2 more
doaj +2 more sources
International Journal of Infectious Diseases, 2017 Objectives: The aim of this study was to evaluate whether rifabutin can improve treatment outcomes in patients with rifabutin-sensitive MDR-TB. Methods: A retrospective cohort study was performed on 76 patients with rifabutin-sensitive MDR-TB who were ...
Soohyun Ahn, Na-Young Hwang, Hee Jae Huh
exaly +3 more sources
Single-ascending and multiple-ascending dose study of the pharmacokinetics, safety, and tolerability of BV100 (rifabutin for infusion) in healthy volunteers [PDF]
Antimicrobial Agents and ChemotherapyBV100 (rifabutin for infusion) is being developed as an intravenous formulation for treating serious or life-threatening infections due to carbapenem-resistant Acinetobacter baumannii in patients with limited treatment options.
Christian Kemmer +6 more
doaj +2 more sources
Sequence of Antibiotic Administration for the Treatment of Mycobacterium avium subsp. hominissuis Infection Might Influence the Response Outcome [PDF]
AntibioticsBackground/Objectives: Mycobacterium avium subsp. hominissuis is a cause of disseminated infections in immunosuppressed patients and pulmonary infections in individuals with chronic lung conditions.
Amy Leestemaker-Palmer +2 more
doaj +2 more sources
A Case Series of Rifabutin Use in Staphylococcal Prosthetic Infections
Microbiology Spectrum, 2022 This case series describes seven patients who received rifabutin in place of rifampin combined with conventional antimicrobial therapy for treatment of hardware-associated staphylococcal infections.
Miranda Monk +4 more
doaj +1 more source
Pharmacokinetics of rifabutin in Japanese HIV-infected patients with or without antiretroviral therapy. [PDF]
PLoS ONE, 2013 OBJECTIVE: Based on drug-drug interaction, dose reduction of rifabutin is recommended when co-administered with HIV protease inhibitors for human immunodeficiency virus (HIV)-associated mycobacterial infection.
Junko Tanuma +10 more
doaj +1 more source
Low-dose rifabutin-induced uveitis with premature occurrence: A case series of rare presentation
Indian Journal of Ophthalmology. Case Reports, 2022 Rifabutin is a known-drug prescribed for prophylaxis and treatment of Mycobacterium avium complex (MAC) and causes dose-related anterior uveitis in immunocompromised individuals, particularly, those infected with HIV.
Sumedha Vats +4 more
doaj +1 more source
Rifabutin-Cobicistat Drug Interaction Resulting in Severe Bilateral Panuveitis
Case Reports in Ophthalmology, 2020 We report a novel case of severe bilateral panuveitis with hypopyon secondary to rifabutin and cobicistat drug interaction in the setting of human immunodeficiency virus (HIV) infection and latent tuberculosis (TB).
Christopher B. Toomey +2 more
doaj +1 more source
Microbiology Spectrum, 2021 After staphylococci, streptococci and enterococci are the most frequent causes of periprosthetic joint infection (PJI). MICs and minimum biofilm bactericidal concentrations of rifampin, rifabutin, and rifapentine were determined for 67 enterococcal and ...
Mariana Albano +7 more
doaj +1 more source