Results 31 to 40 of about 5,853 (155)

Rifabutin corneal deposits localized to the deep stroma using anterior segment optical coherence tomography

American Journal of Ophthalmology Case Reports, 2020
Purpose: To demonstrate that rifabutin-related corneal deposits are localized to the deep stroma using anterior segment optical coherence tomography (OCT) and confocal microscopy.
Tianyi Zhang, Catherine Q. Sun, Yijie B. Lin, Julie M. Schallhorn   +3 more
doaj   +1 more source

Exploring Alternative Treatment Choices for Multidrug-Resistant Clinical Strains of Helicobacter pylori in Mongolia

Microorganisms, 2023
Helicobacter pylori is a pathogen related to severe diseases such as gastric cancer; because of rising antimicrobial-resistant strains, failure to eradicate H. pylori with antibiotics has increased worldwide. Multidrug-resistant H.
Ayush Khangai, Batsaikhan Saruuljavkhlan, Dashdorj Azzaya, Boldbaatar Gantuya, Khasag Oyuntsetseg, Junko Akada, Takashi Matsumoto, Yoshio Yamaoka   +7 more
doaj   +1 more source

Rifabutin Use in Staphylococcus Biofilm Infections: A Case Series

Antibiotics, 2020
This is a case series of 10 patients who had staphylococcal biofilm infections that were treated with adjuvant rifabutin therapy instead of rifampin therapy.
James B. Doub, Emily L. Heil, Afua Ntem-Mensah, Renaldo Neeley, Patrick R. Ching   +4 more
doaj   +1 more source

Molecular docking analysis and antidiabetic activity of Rifabutin against STZ-NA induced diabetes in albino wistar rats

Beni-Suef University Journal of Basic and Applied Sciences, 2017
Computer Aided Drug Design (CADD) molecular docking program used in this study and as a result Rifabutin was retrieved as structurally similar drug molecule to Lixisenatide (A widely used GLP-1 agonist).
Danish Ahmed, Mohd. Ibrahim Khan, Gaurav Kaithwas, Subhadeep Roy, Swetlana Gautam, Manjari Singh, Uma Devi, Rajnish Yadav, Jitendra Rawat, Shubhini Saraf   +9 more
doaj   +1 more source

Defining the minimum inhibitory concentration of 22 rifamycins in iron limited, physiologic medium against Acinetobacter baumannii, Escherichia coli, and Klebsiella pneumoniae clinical isolates.

PLoS ONE, 2023
Recently, we reported rifabutin hyper-activity against Acinetobacter baumannii. We sought to characterize if any additional rifamycins (n = 22) would also display hyper-activity when tested in iron-limited media against A. baumannii, K. pneumoniae, and E.
Peggy Lu, Francesco Alletto, Bosul Lee, Elizabeth Burk, Jasmine Martinez, Fabio Prati, Emilia Caselli, Brad Spellberg, Brian Luna   +8 more
doaj   +1 more source

Pharmacokinetic features of dolutegravir with rifampicin and rifabutin among patients coinfected with human immunodeficiency virus and tuberculosis/mycobacterium avium complex

International Journal of Infectious Diseases, 2022
Background: Rifamycins are the cornerstone of anti-tuberculosis therapy while they are potent inducers of drug metabolizing enzymes. For the first time, we evaluated the effect of rifampicin (RIF) and rifabutin (RBT) on the pharmacokinetics (PK) of ...
Xiaoqin Le, Xiaoye Guo, Jianjun Sun, Li Liu, Yinzhong Shen, Jiangrong Wang, Tangkai Qi, Zhenyan Wang, Yang Tang, Wei Song, Lin Yin, Lijun Zhang, Renfang Zhang, Jun Chen   +13 more
doaj   +1 more source

A drug interaction study investigating the effect of Rifabutin on the pharmacokinetics of Maraviroc in healthy subjects.

PLoS ONE, 2019
Effects of steady-state rifabutin on the pharmacokinetics of steady-state maraviroc were investigated in fourteen healthy adult female and male volunteers. Maraviroc 300 mg twice daily (BID) was given orally with food for fifteen days.
M Ghannad, M Dennehy, C la Porte, I Seguin, D Tardiff, R Mallick, E Sabri, G Zhang, S Kanji, D W Cameron   +9 more
doaj   +1 more source

Acquisition of rifabutin resistance by a rifampicin resistant mutant of Mycobacterium tuberculosis involves an unusual spectrum of mutations and elevated frequency

Annals of Clinical Microbiology and Antimicrobials, 2005
Background Mutations in a small region of the rpoB gene are responsible for most rifamycin resistance in Mycobacterium tuberculosis. In this study we have sequentially generated resistant strains to first rifampicin and then rifabutin.
Oskam Linda, Brown Tim J, Bergval Indra L, Schuitema Anja RJ, Anthony Richard M, Klatser Paul R   +5 more
doaj   +1 more source

Acute panuveitis with hypopyon in Crohn's disease secondary to medical therapy: a case report

Journal of Medical Case Reports, 2007
Background A case report to highlight the association between rifabutin and hypopyon Methods A 56 year old male presented with a one day history of blurred vision in his right eye. He had an established diagnosis of Crohn's disease which was in remission
Haider David, Dhawahir-Scala Felipe E, Strouthidis Nicholas G, Davies Nigel   +3 more
doaj   +1 more source

Comparison of Compartmental and Non-Compartmental Analysis to Detect Biopharmaceutical Similarity of Intravenous Nanomaterial-Based Rifabutin Formulations

Pharmaceutics, 2023
Pharmacometric analysis is often used to quantify the differences and similarities between formulation prototypes. In the regulatory framework, it plays a significant role in the evaluation of bioequivalence.
Nadezhda Osipova, Andrey Budko, Olga Maksimenko, Elena Shipulo, Ludmila Vanchugova, Wenqian Chen, Svetlana Gelperina, Matthias G. Wacker   +7 more
doaj   +1 more source