Results 31 to 40 of about 7,683 (166)

[Rifabutin-associated with bilateral uveitis in an HIV negative patient]

, 2008
BACKGROUND: Rifabutin-associated uveitis has often been described in patients with HIV. We present the case of a bilateral non-granulomatous uveitis in an HIV negative patient on rifabutin therapy.
Orgül, S., Müller, K., Grieshaber, M. C.   +2 more
core   +2 more sources

Rifabutin-induced cystoid macular oedema.

, 2002
Rifabutin is a semi-synthetic antimycobacterial agent mainly used in the treatment of Mycobacterium avium-complex (MAC) in AIDS patients. Rifabutin-induced anterior uveitis has been reported previously.
Guex-Crosier, Y., Vaudaux, J.D.
core   +1 more source

Acquisition of rifabutin resistance by a rifampicin resistant mutant of Mycobacterium tuberculosis involves an unusual spectrum of mutations and elevated frequency

Annals of Clinical Microbiology and Antimicrobials, 2005
Background Mutations in a small region of the rpoB gene are responsible for most rifamycin resistance in Mycobacterium tuberculosis. In this study we have sequentially generated resistant strains to first rifampicin and then rifabutin.
Oskam Linda, Brown Tim J, Bergval Indra L, Schuitema Anja RJ, Anthony Richard M, Klatser Paul R   +5 more
doaj   +1 more source

Defining the minimum inhibitory concentration of 22 rifamycins in iron limited, physiologic medium against Acinetobacter baumannii, Escherichia coli, and Klebsiella pneumoniae clinical isolates.

PLoS ONE, 2023
Recently, we reported rifabutin hyper-activity against Acinetobacter baumannii. We sought to characterize if any additional rifamycins (n = 22) would also display hyper-activity when tested in iron-limited media against A. baumannii, K. pneumoniae, and E.
Peggy Lu, Francesco Alletto, Bosul Lee, Elizabeth Burk, Jasmine Martinez, Fabio Prati, Emilia Caselli, Brad Spellberg, Brian Luna   +8 more
doaj   +1 more source

Acute panuveitis with hypopyon in Crohn's disease secondary to medical therapy: a case report

Journal of Medical Case Reports, 2007
Background A case report to highlight the association between rifabutin and hypopyon Methods A 56 year old male presented with a one day history of blurred vision in his right eye. He had an established diagnosis of Crohn's disease which was in remission
Haider David, Dhawahir-Scala Felipe E, Strouthidis Nicholas G, Davies Nigel   +3 more
doaj   +1 more source

Pharmacokinetic features of dolutegravir with rifampicin and rifabutin among patients coinfected with human immunodeficiency virus and tuberculosis/mycobacterium avium complex

International Journal of Infectious Diseases, 2022
Background: Rifamycins are the cornerstone of anti-tuberculosis therapy while they are potent inducers of drug metabolizing enzymes. For the first time, we evaluated the effect of rifampicin (RIF) and rifabutin (RBT) on the pharmacokinetics (PK) of ...
Xiaoqin Le, Xiaoye Guo, Jianjun Sun, Li Liu, Yinzhong Shen, Jiangrong Wang, Tangkai Qi, Zhenyan Wang, Yang Tang, Wei Song, Lin Yin, Lijun Zhang, Renfang Zhang, Jun Chen   +13 more
doaj   +1 more source

Summary of the steady-state pharmacokinetics for Rifabutin and 25-O-desacetyl rifabutin (Day 15)^a.

, 2019
Summary of the steady-state pharmacokinetics for Rifabutin and 25-O-desacetyl rifabutin (Day 15)a.
E. Sabri (7542692), C. la Porte (7542683), G. Zhang (808141), M. Ghannad (7542677), R. Mallick (5874875), M. Dennehy (7542680), S. Kanji (3407216), D. W. Cameron (7542695), I. Seguin (7542686), D. Tardiff (7542689)   +9 more
core   +1 more source

Mean plasma concentrations-versus-time plots of rifabutin (A), 25-O-desacetyl rifabutin (B), and rifabutin plus 25-O-desacetylrifabutin (C).

, 2013
Nine patients of Group I received 300 mg of rifabutin and 7 patients of Group II received 150 mg of rifabutin every other day with lopinavir/ritonavir-containing antiretroviral therapy. Solid circles: Group I, open circles: Group II.
Junko Tanuma (205450), Takahiro Aoki (212477), Koji Watanabe (205444), Haruhito Honda (212482), Kunihisa Tsukada (212489), Hiroyuki Gatanaga (205448), Yoshimi Kikuchi (212497), Katsuji Teruya (212494), Hirohisa Yazaki (212487), Kazumi Sano (441666), Shinichi Oka (205454)   +10 more
core   +1 more source

Long‐Acting Therapeutics in Pediatric Health: Bridging Innovation and Access

Clinical Pharmacology &Therapeutics, EarlyView.
Children have distinct therapeutic needs arising from age‐dependent physiology, disease epidemiology, formulation requirements, dosing considerations, and safety vulnerabilities. Despite substantial reductions in childhood mortality over the past three decades, nearly 5 million children under five died in 2023, with infectious diseases continuing to ...
Prajith Venkatasubramanian, Moherndran Archary, Daniel B. Hawcutt, Rachel Daley, Edmund Capparelli, Adeniyi Olagunju   +5 more
wiley   +1 more source

Comparison of Compartmental and Non-Compartmental Analysis to Detect Biopharmaceutical Similarity of Intravenous Nanomaterial-Based Rifabutin Formulations

Pharmaceutics, 2023
Pharmacometric analysis is often used to quantify the differences and similarities between formulation prototypes. In the regulatory framework, it plays a significant role in the evaluation of bioequivalence.
Nadezhda Osipova, Andrey Budko, Olga Maksimenko, Elena Shipulo, Ludmila Vanchugova, Wenqian Chen, Svetlana Gelperina, Matthias G. Wacker   +7 more
doaj   +1 more source