Results 1 to 10 of about 28,118 (222)

Altered Mycobacterium tuberculosis Cell Wall Metabolism and Physiology Associated With RpoB Mutation H526D

Frontiers in Microbiology, 2018
Background:Mycobacterium tuberculosis (Mtb) rpoB mutations are associated with global metabolic remodeling. However, the net effects of rpoB mutations on Mtb physiology, metabolism and function are not completely understood.
Thomas R Ioerger, Dalin Rifat, Petros C Karakousis   +2 more
exaly   +4 more sources

GENE MUTATION PATTERNS OF RIFAMPICIN IN MULTIDRUG RESISTANT MYCOBACTERIUM TUBERCULOSIS COMPLEX STRAINS

İstanbul Tıp Fakültesi Dergisi, 2022
Objective: The aim of this study was to evaluate the GenoType®MTBDRplus test for detection of rifampicin (RIF) resistance in MDR Mycobacterium tuberculosis complex strains.
Esra Yıldırım Servi, Meltem Uzun
doaj   +1 more source

Rifampicin resistance conferring mutations among Mycobacterium tuberculosis strains in Rwanda

International Journal of Mycobacteriology, 2023
Background: The World Health Organization-endorsed phenotypic and genotypic drug-susceptibility testing (gDST/pDST) assays for the detection of rifampicin-resistant (RR) tuberculosis (TB), may miss some clinically relevant rpoB mutants, including ...
Isabel Cuella-Martin, Jean Claude Semuto Ngabonziza, Gabriela Torrea, Conor Joseph Meehan, Wim Mulders, Bertin Ushizimpumu, Louise De Weerdt, Jelle Keysers, Willem Bram De Rijk, Tom Decroo, Bouke C De Jong, Leen Rigouts   +11 more
doaj   +1 more source

Drug-resistant Tuberculosis: First Line Drug Resistance Pattern among Mycobacterium Tuberculosis Strains Isolated from a Reference Laboratory in Kerala State, India

Journal of Pure and Applied Microbiology, 2021
Resistance to antimycobacterial agents consistently remains a major obstacle to end TB in India. Geographical prevalence data regarding drug-resistant evolutionary genetics of M. tuberculosis (MTB) remains sparse in India. Our objective was to determine
Neetha S Murthy, Sanjeev Nair, PK Ramya, Renu Susan George, B Ravikrishnan, M Sunil Kumar, Sairu Philip, PS Rakesh, Shibu Balakrishnan   +8 more
doaj   +1 more source

Determination of potentially novel compensatory mutations in rpoc associated with rifampin resistance and rpob mutations in Mycobacterium tuberculosis Clinical isolates from peru

International Journal of Mycobacteriology, 2020
Background: Rifampicin (RIF) resistance in Mycobacterium tuberculosis is frequently caused by mutations in the rpoB gene. These mutations are associated with a fitness cost, which can be overcome by compensatory mutations in other genes, among which rpoC
Ana Paula Vargas, Angela A Rios, Louis Grandjean, Daniela E Kirwan, Robert H Gilman, Patricia Sheen, Mirko J Zimic   +6 more
doaj   +1 more source

Identification of antimicrobial resistance determinants in Mycobacterium leprae using SNaPshot technique [PDF]

Клиническая микробиология и антимикробная химиотерапия
Objective. The development of a method for identifying frequent genetic determinants of Mycobacterium leprae clinical isolates resistance to three groups of antimicrobial drugs: dapsone, rifampicin and fluoroquinolones using SNaPshot technique ...
Verbenko D.A., Solomka V.S., Deryabin D.G., Levicheva Yu.Yu., Karamova A.E., Kubanov A.A.   +5 more
doaj   +1 more source

Acinetobacter Strain KUO11TH, a Unique Organism Related to Acinetobacter pittii and Isolated from the Skin Mucus of Healthy Bighead Catfish and Its Efficacy Against Several Fish Pathogens

Microorganisms, 2019
The bacterial strain KU011TH was isolated from the skin mucus of healthy bighead catfish. The strain is a Gram-negative coccobacillus that is nonmotile, aerobic, catalase positive, oxidase negative, and nonhemolytic. Sequence analyses of the housekeeping
Anurak Bunnoy, Uthairat Na-Nakorn, Pattanapon Kayansamruaj, Prapansak Srisapoome   +3 more
doaj   +1 more source

Detection and characterization of endophytic bacteria causing knot in young olive trees

Acta Agriculturae Slovenica, 2019
Olive knot is an important disease in most countries where olives are commercially grown. In the spring of 2015, some galls were observed on the trunk and branches of 4-year-old olive trees in the north of Iran.
Maryam KHEZRI, Abolghasem GHASEMI, Akbar AHANGARAN   +2 more
doaj   +1 more source

Importance of Detection of Isoniazid and Rifampicin Mono Drug Resistance and Determining Rate of MDR-TB in Smear Positive Sputum Samples from a Tertiary Care Hospital of West U.P. India

Journal of Pure and Applied Microbiology, 2019
Anti-tubercular therapy is one of the effective strategies used to control tuberculosis, so, a planned and accurate treatment regimen is of utmost importance, but number of cases are being treated as MDR on the basis of rifampicin mono resistance.
Sana Nudrat, Umar Farooq, Mazhar Maqsood
doaj   +1 more source

Coamplification of Mycobacterium leprae genome sections by real-time PCR: Detection of the pathogen and the possibility of a semi-quantitative assessment of the bacterial load

Vestnik Dermatologii i Venerologii, 2020
Aim. To develop a method for coamplification of single-copy genes and repetitive elements of the Mycobacterium leprae genome in the analysis of clinical material from leprosy patients with an assessment of the clinical significance of the study results ...
D. A. Verbenko, A. E. Karamova, V. S. Solomka, A. A. Kubanov, D. G. Deryabin   +4 more
doaj   +1 more source