Antibiotics, 2023 Background. Rifampicin is a pillar in the treatment of periprosthetic joint infection (PJI). However, rifampicin resistance is an increasing threat to PJI treatment.
Stergios Lazarinis +3 more
doaj +4 more sources
Journal of Global Antimicrobial Resistance, 2020 Objectives: Study of the rifampicin resistance of Rhodococcus equi strains isolated from French horses over a 20-year period. Methods: Rifampicin susceptibility was tested by disk diffusion (DD) and broth macrodilution methods, and rpoB gene sequencing ...
Sandrine Petry +10 more
doaj +3 more sources
Constrained RNA polymerase mutational pathways distinguish corallopyronin A resistance from rifampicin resistance in staphylococci [PDF]
Scientific ReportsCorallopyronin A (CorA) is a natural RNA polymerase (RNAP) inhibitor active against Gram-positive pathogens, including Staphylococcus aureus. Although spontaneous resistance to CorA occurs less frequently than to rifampicin, the genetic basis and ...
Jesenko Karačić +7 more
doaj +2 more sources
Annual trends in Mycobacterium tuberculosis detection and rifampicin resistance at a regional referral hospital in Northern Ghana, 2019-2024. [PDF]
PLoS ONEBackground Tuberculosis (TB) remains an important public health problem in Ghana, while rifampicin-resistant TB (RR-TB) poses an additional challenge to TB control.
Solomon Wireko +8 more
doaj +2 more sources
Can resistance to either isoniazid or rifampicin predict multidrug resistance tuberculosis (MDR-TB)
Bulletin of the National Research Centre, 2023 Background Previous studies have shown significant differences and lack clarity on whether resistance to either isoniazid or rifampicin can predict multidrug resistance tuberculosis (MDR-TB).
Betty R. Mchaki +3 more
doaj +2 more sources
Prevalence of rifampicin resistance in pulmonary tuberculosis: A laboratory-based study. [PDF]
PLOS Global Public HealthTuberculosis (TB) remains a significant global public health challenge, particularly in low- and middle-income countries. The emergence of rifampicin-resistant tuberculosis further complicates control efforts.
Israel Bedzina +9 more
doaj +2 more sources
Prevalence and associated factors of rifampicin resistance pulmonary tuberculosis among HIV-positive patients in Bahir Dar, Northwest, Ethiopia [PDF]
Scientific ReportsTuberculosis (TB) remains a major public health problem and a leading cause of morbidity and mortality among people living with HIV, particularly in high-burden countries such as Ethiopia. TB control is severely compromised by rifampicin-resistant TB (RR-
Alemayehu Abate +2 more
doaj +2 more sources
Journal of Global Antimicrobial Resistance, 2022 Objectives: Rifampicin plays a key role in the management of prosthetic joint infections (PJIs); however, the emergence of rifampicin resistance is associated with less favourable clinical outcomes. The purpose of this study was to investigate the impact
Gergely Krizsan +5 more
doaj +3 more sources
HflX mediates rifampicin resistance in Brucella by downregulating the expression of RNA polymerase-associated genes [PDF]
Frontiers in MicrobiologyBrucella species (Brucella spp.) are facultative intracellular zoonotic pathogens responsible for brucellosis, a disease causing substantial global public health and economic burdens.
Hao Geng +14 more
doaj +2 more sources
Frontiers in Chemistry, 2019 Tuberculosis is still one of the top 10 causes of deaths worldwide, especially with the emergence of multidrug-resistant tuberculosis. Rifampicin, as the most effective first-line antituberculosis drug, also develops resistance due to the mutation on ...
Qianqian Zhang +5 more
doaj +3 more sources