Results 21 to 30 of about 3,000 (187)

Global prevalence of resistance to rifampicin in Mycobacterium leprae: A meta-analysis

open access: yesJournal of Global Antimicrobial Resistance, 2022
Objectives: As the only bactericidal drug in multidrug therapy is rifampicin, monitoring of antimicrobial resistance is important in leprosy patients. Therefore, we conducted a meta-analysis on the resistance of Mycobacterium leprae (M.
Chen Wang   +6 more
doaj   +1 more source

AASLD practice guidance on drug, herbal, and dietary supplement–induced liver injury

open access: yes, 2022
Hepatology, EarlyView.
Robert J. Fontana   +6 more
wiley   +1 more source

Molecular characterization of resistance to Rifampicin in an emerging hospital-associated Methicillin-resistant Staphylococcus aureus clone ST228, Spain

open access: yesBMC Microbiology, 2010
Background Methicillin-resistant S. aureus (MRSA) has been endemic in Hospital Universitari de Bellvitge, Barcelona, since 1990. During the 1990-95 period the Iberian clone (ST-247; SCCmec-I) was dominant. Isolates of clonal complex 5 (ST-125; SCCmec-IV)
Liñares Josefina   +5 more
doaj   +1 more source

Systematic review of the performance of rapid rifampicin resistance testing for drug-resistant tuberculosis.

open access: yesPLoS ONE, 2013
IntroductionRapid tests for rifampicin resistance may be useful for identifying isolates at high risk of drug resistance, including multidrug-resistant TB (MDR-TB).
Matthew Arentz   +3 more
doaj   +1 more source

Whole-genome sequencing for surveillance of fluoroquinolone resistance in rifampicin-susceptible tuberculosis in a rural district of Shanghai: A 10-year retrospective study

open access: yesFrontiers in Public Health, 2022
BackgroundFluoroquinolones (FQs) are the most important second-line anti-tuberculosis (anti-TB) drugs, primarily used for the treatment of multidrug- or rifampicin-resistant TB (MDR/RR-TB).
Yangyi Zhang   +14 more
doaj   +1 more source

Rifampicin Resistance Associated with rpoB Mutations in Neisseria gonorrhoeae Clinical Strains Isolated in Austria, 2016 to 2020

open access: yesMicrobiology Spectrum, 2022
Due to increasing rates of antimicrobial resistance (AMR) in Neisseria gonorrhoeae, alternative treatments should be considered. To assess rifampicin’s potential as a gonorrhea treatment, we used rpoB mutations to estimate rifampicin resistance in ...
Justine Schaeffer   +11 more
doaj   +1 more source

Inactivation of a New Potassium Channel Increases Rifampicin Resistance and Induces Collateral Sensitivity to Hydrophilic Antibiotics in Mycobacterium smegmatis

open access: yesAntibiotics, 2022
Rifampicin is a critical first-line antibiotic for treating mycobacterial infections such as tuberculosis, one of the most serious infectious diseases worldwide.
Thi Thuy Do   +5 more
doaj   +1 more source

Isoniazid resistance profile and associated levofloxacin and pyrazinamide resistance in rifampicin resistant and sensitive isolates/from pulmonary and extrapulmonary tuberculosis patients in Pakistan: A laboratory based surveillance study 2015-19.

open access: yesPLoS ONE, 2020
BackgroundPakistan is among top five high burden countries for tuberculosis and drug resistant TB. Among rifampicin sensitive new pulmonary TB (PTB), prevalence of isoniazid resistance is 8.3% (95%CI: 7.0-10.7) and resistance to fluoroquinolone is higher
Sabira Tahseen   +6 more
doaj   +1 more source

False rifampicin resistant results using Xpert MTB/RIF on urine samples in hospitalised HIV-infected patients

open access: yesSouthern African Journal of HIV Medicine, 2019
Background: A small proportion of false rifampicin resistant results have previously been reported using GeneXpert MTB/RIF version G4 on sputum samples; however, this has not been investigated for urine samples in HIV-associated tuberculosis (TB ...
Charlotte Schutz   +6 more
doaj   +1 more source

Diagnosis of rifampicin-resistant tuberculosis: Discordant results by diagnostic methods

open access: yesAfrican Journal of Laboratory Medicine, 2018
The performance of the Xpert© MTB/RIF and MTBDRplus assays for the detection of rifampicin resistant Mycobacterium tuberculosis was compared to culture-based drug susceptibility testing in 30 specimens with rifampicin-resistant and rifampicin ...
Winnie Mwanza   +8 more
doaj   +1 more source

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