Results 41 to 50 of about 1,627 (196)
Atom-efficient multicomponent reactions (MCR) and step-efficient one-pot synthesis are developed for the synthesis of biaryl-substituted furocoumarins, furoquinolones, and furopyrimidines.
Kadam Asha +2 more
doaj +1 more source
Novel Mitochondria-Targeted Furocoumarin Derivatives as Possible Anti-Cancer Agents
Targeting small molecules to appropriate subcellular compartments is a way to increase their selectivity and effectiveness while minimizing side effects.
Andrea Mattarei +9 more
doaj +1 more source
Doxorubicin (DOX) induced myocardial toxicity may limit its therapeutic use in clinic. Psoralen (PSO), a major active tricyclic furocoumarin extracted from Psoralea corylifolia, is widely used as an antineoplastic agent in treatment of leukemia and other
Fansu Meng +8 more
doaj +1 more source
Investigations into heat- and light-induced terpene modifications in essential oils [PDF]
Essential oils belong to secondary plant metabolites, with terpenoids and phenylpropanoids being among the main constituents in terms of quantity. Due to their lipophilic character and high volatility, they are mainly obtained by steam distillation ...
Bitterling, Hannes
core
ABSTRACT The review examines the evolution of chemical ionization mass spectrometry (CI‐MS), a technique developed in 1966 by Field and Munson. CI is a soft‐ionization method that produces more intense molecular ions with less fragmentation than electron ionization (EI).
Malvika Dutt +4 more
wiley +1 more source
Notopterol Attenuates Monocrotaline-Induced Pulmonary Arterial Hypertension in Rat
IntroductionCurrent targeted pulmonary arterial hypertension (PAH) therapies have improved lung hemodynamics, cardiac function, and quality of life; however, none of these have reversed the ongoing remodeling of blood vessels.
Lin Huang +10 more
doaj +1 more source
ABSTRACT Aim(s) This cross‐sectional clinical study aimed to explore the untargeted metabolomic and lipidomic profiles in gingival crevicular fluid (GCF) obtained from healthy individuals and patients with periodontitis. Materials and Methods GCF was collected from 17 periodontally healthy and 19 periodontitis patients.
Caroline H. Henderzahs +6 more
wiley +1 more source
Globally, urinary tract infections (UTIs) are one of the most frequent bacterial infections. Uropathogenic Escherichia coli (UPEC) are the predominant etiological agents causing community and healthcare-associated UTIs.
Harpreet Kaur +7 more
doaj +1 more source
Trending Topics on Coumarin and Its Derivatives in 2020 [PDF]
Coumarins are naturally occurring molecules with a versatile range of activities. Their structural and physicochemical characteristics make them a privileged scaffold in medicinal chemistry and chemical biology. Many research articles and reviews compile
Carneiro Viqueira, Aitor +3 more
core +1 more source
Imperatorin Mitigates Rosacea‐Like Inflammation by Modulating the Crosstalk Between JNK1 and STAT1
IMP treatment disrupts the interaction between JNK1 and STAT1, thereby attenuating STAT1 activity. This interference subsequently diminishes the phosphorylation and nuclear translocation of STAT1, which ultimately results in a reduced production of inflammatory cytokines and chemokines.
Xiaoxue Wang, Zexin Zhu
wiley +1 more source

