Results 41 to 50 of about 1,650 (211)

Atom- and step-economic synthesis of biaryl-substituted furocoumarins, furoquinolones and furopyrimidines by multicomponent reactions and one-pot synthesis

open access: yesGreen Processing and Synthesis, 2013
Atom-efficient multicomponent reactions (MCR) and step-efficient one-pot synthesis are developed for the synthesis of biaryl-substituted furocoumarins, furoquinolones, and furopyrimidines.
Kadam Asha   +2 more
doaj   +1 more source

Novel Mitochondria-Targeted Furocoumarin Derivatives as Possible Anti-Cancer Agents

open access: yesFrontiers in Oncology, 2018
Targeting small molecules to appropriate subcellular compartments is a way to increase their selectivity and effectiveness while minimizing side effects.
Andrea Mattarei   +9 more
doaj   +1 more source

Anti-Neuroinflammatory Components from Clausena lenis Drake

open access: yesMolecules, 2022
Clausena lenis Drake (C. lenis) is a folk medicinal herb to treat influenza, colds, bronchitis, and malaria. The 95% and 50% ethanol extract of C. lenis showed significant nitric oxide (NO) inhibition activity in BV-2 microglial cells stimulated by ...
Si-Si Zhu   +5 more
doaj   +1 more source

Seville orange juice‐felodipine interaction: Comparison with dilute grapefruit juice and involvement of furocoumarins [PDF]

open access: yes, 2001
Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/109875/1/cptclpt20013 ...
Bailey, David G.   +3 more
core   +1 more source

Chemical Ionization Mass Spectrometry: Fundamental Principles, Diverse Applications, and the Latest Technological Frontiers

open access: yesMass Spectrometry Reviews, EarlyView.
ABSTRACT The review examines the evolution of chemical ionization mass spectrometry (CI‐MS), a technique developed in 1966 by Field and Munson. CI is a soft‐ionization method that produces more intense molecular ions with less fragmentation than electron ionization (EI).
Malvika Dutt   +4 more
wiley   +1 more source

Protective effects of psoralen polymer lipid nanoparticles on doxorubicin - induced myocardial toxicity

open access: yesBrazilian Journal of Pharmaceutical Sciences, 2022
Doxorubicin (DOX) induced myocardial toxicity may limit its therapeutic use in clinic. Psoralen (PSO), a major active tricyclic furocoumarin extracted from Psoralea corylifolia, is widely used as an antineoplastic agent in treatment of leukemia and other
Fansu Meng   +8 more
doaj   +1 more source

Laser Microirradiation of Chinese Hamster Cells at Wavelength 365 nm [PDF]

open access: yes, 1981
Cells of a V79 subline of the Chinese hamster were microirradiated at wavelength 365 nm in the presence of the psoralen derivative, trioxsalen. Microirradiation was accomplished by a pulsed argon laser microbeam either in anaphase or in interphase 3 hr ...
Berns, Michael W.   +3 more
core  

Multi‐Targeting Ligands as Prospective Therapeutics for Alzheimer's Disease, a Prevalent Neurodegenerative Disorder: Mechanistic Insights, Emerging Targets and Drug Discovery Campaigns

open access: yesMedicinal Research Reviews, EarlyView.
ABSTRACT Alzheimer's disease (AD) is a debilitating neurodegenerative condition characterized by progressive cognitive impairment, memory deterioration, and neuronal dysfunction. Its complex pathophysiology involves multiple interlinked processes, including amyloid‐β (Aβ) aggregation, tau hyperphosphorylation, oxidative stress, neuroinflammation ...
Amandeep Thakur   +6 more
wiley   +1 more source

New Synthetic Routes to Furocoumarins and Their Analogs: A Review

open access: yesMolecules, 2004
Many furocoumarins and their analogs possess a prominent photobiological activity. Some of them are successfully used as drugs in phototherapy of skin diseases. Fries rearrangement of acyloxyheteroarenes, condensation of acylhydroxyheteroarenes with α-
Valery F. Traven
doaj   +1 more source

Notopterol Attenuates Monocrotaline-Induced Pulmonary Arterial Hypertension in Rat

open access: yesFrontiers in Cardiovascular Medicine, 2022
IntroductionCurrent targeted pulmonary arterial hypertension (PAH) therapies have improved lung hemodynamics, cardiac function, and quality of life; however, none of these have reversed the ongoing remodeling of blood vessels.
Lin Huang   +10 more
doaj   +1 more source

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