Results 71 to 80 of about 1,627 (196)

Protective Effect of Bergapten against Human Erythrocyte Hemolysis and Protein Denaturation In Vitro

International Journal of Inflammation, 2021
Bergapten, a furocoumarin found in many medicinal plants, is used for the management of various conditions. The present in vitro study evaluated the ability of bergapten to prevent human erythrocyte hemolysis and protein denaturation.
Douglas Bosco Aidoo, Daniels Konja, Isaac Tabiri Henneh, Martins Ekor   +3 more
doaj   +1 more source

The effects of post‐harvest pretreatments and drying methods on in vitro bioaccessibility of phenolics and carotenoids in tomato (Solanum lycopersicum) cultivars

Journal of Food Science, Volume 90, Issue 2, February 2025.
Abstract Two pretreatments (ultrasound sonication [US] and microwave [MW]) and drying techniques (hot air [HA] and freeze‐drying [FD]) were used to assess the in vitro bioaccessibility of phenols, carotenoids, and antioxidant activity in three tomato cultivars (Zzx171, Zzx162, and Zzx65). The metabolome‐chemometric analysis showed that tomato cultivars
Nokuthula Abegale Nzimande, Sephora Mutombo Mianda, Faith Seke, Dharini Sivakumar   +3 more
wiley   +1 more source

Synthesis and Cytotoxic Activity of a New Group of Heterocyclic Analogues of the Combretastatins

Molecules, 2014
A series of new analogs of combretastatin A-4 (CA-4, 1) with the A or B-ring replaced by a 3-oxo-2,3-dihydrofurocoumarin or a furocoumarin residue have been designed and synthesized by employing a cross-coupling approach. All the compounds were evaluated
Alla V. Lipeeva, Elvira E. Shults, Makhmut M. Shakirov, Mikhail A. Pokrovsky, Andrey G. Pokrovsky   +4 more
doaj   +1 more source

The Antiproliferative Activity of Oxypeucedanin via Induction of G₂/M Phase Cell Cycle Arrest and p53-Dependent MDM2/p21 Expression in Human Hepatoma Cells

Molecules, 2020
Oxypeucedanin (OPD), a furocoumarin compound from Angelica dahurica (Umbelliferae), exhibits potential antiproliferative activities in human cancer cells.
So Hyun Park, Ji-Young Hong, Hyen Joo Park, Sang Kook Lee   +3 more
doaj   +1 more source

Gas Chromatography–Mass Spectroscopy (GC–MS) Simultaneous Determination of Limonene, Linalool, and Linalyl Acetate in Rat Plasma Following Transdermal Administration of the Essential Oil of Bergamot Loaded Onto Solid Lipid Nanoparticles (NanoBEO)

Phytotherapy Research, Volume 40, Issue 2, Page 488-492, February 2026.
Luigi A. Morrone, Laura Rombolà, Antonella Leggio, Emilia L. Belsito, Ludovica Scorzafave, Enrica De Rasis, Martina Pagliaro, Kengo Hamamura, Takafumi Hayashi, Giacinto Bagetta, Maria Tiziana Corasaniti, Damiana Scuteri   +11 more
wiley   +1 more source

Recent Perspectives on Anticancer Potential of Coumarin Against Different Human Malignancies: An Updated Review

Food Science &Nutrition, Volume 13, Issue 1, January 2025.
The paper highlights coumarin's ability to induce apoptosis, inhibit cell proliferation, and interfere with cancer cell signaling pathways. Coumarin disrupts key signaling pathways, including NF‐κB and PI3K/Akt, which are crucial for cancer cell survival and proliferation.
Muhammad Shahbaz, Asfa Perween, Ushna Momal, Muhammad Imran, Muhammad Hammad Ul Hassan, Hammad Naeem, Ahmed Mujtaba, Muzzamal Hussain, Suliman A. Alsagaby, Waleed Al Abdulmonem, Mohamed A. Abdelgawad, Ahmed H. El‐Ghorab, Samy Selim, Ehab M. Mostafa, Entessar Al Jbawi   +14 more
wiley   +1 more source

Psoralen and Isopsoralen Activate Nuclear Factor Erythroid 2‐Related Factor 2 Through Interaction With Kelch‐Like ECH‐Associated Protein 1

Food Science &Nutrition, Volume 13, Issue 1, January 2025.
Psoralen and its isomer isopsoralen induced the gene and protein expression of Nrf2‐mediated antioxidant targets. Psoralen and isopsoralen activate Nrf2 through interaction with Keap1. The molecular basis for the binding of psoralen and isopsoralen to Keap1 is explored.
Chengyu Lv, Song Wang, Chang Sun, Jing Liu, Yihao Chen, Chao Wang, Cuiping Yuan, Fengxian Qin, Tiezhu Li   +8 more
wiley   +1 more source

Herbal Amara extract induces gastric fundus relaxation via inhibition of the M2 muscarinic receptor

Neurogastroenterology &Motility, Volume 37, Issue 1, January 2025.
This preclinical study demonstrates the relaxant effect of Amara herbal extract (containing nine different plant extracts) on fundus smooth muscles dissected from guinea pigs. This relaxant effect occurs via inhibition of M2 muscarinic receptor activity.
Maria‐Riera Piqué‐Borràs, Johann Röhrl, Gerald Künstle   +2 more
wiley   +1 more source

A furocoumarin, Imperatorin isolated from Urena lobata L. (Malvaceae)

Molbank, 2004
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Keshab Ghosh
doaj   +1 more source

Coumarin analogue 3-methyl-7H-furo[3,2-g] chromen-7-one as a possible antiparkinsonian agent

Biomédica: revista del Instituto Nacional de Salud, 2019
Introduction: Parkinson’s disease is the second most common neurodegenerative disease. Monoamine oxidase B inhibitors are used in the treatment of this disease concomitantly with levodopa or as monotherapy.
María del Pilar Olaya, Nadezdha Esperanza Vergel, José Luis López, María Dolores Viña, Mario Francisco Guerrero   +4 more
doaj   +1 more source