Results 111 to 120 of about 48,888 (227)

Dynamic Variability of Sodium and Potassium Predicts Mortality in Critically Ill Patients With Ischemic Stroke: Evidence From Two Critical Care Cohorts

Brain and Behavior, Volume 16, Issue 9, September 2026.
ABSTRACT Background Ischemic stroke (IS) is one of the leading causes of death and long‐term disability worldwide. Electrolyte fluctuations, particularly in sodium and potassium, may play a critical role in the mortality of IS. Methods This retrospective cohort study utilized the MIMIC‐IV database and NWICU to examine the association between sodium and
Jian Zhang, Wei Zhang, Bin Zeng, Linfeng Xie, Jianjun Zhu   +4 more
wiley   +1 more source

Chronic Kidney Disease in Children Within Five Years After Ifosfamide Chemotherapy for Childhood Cancer: A Dutch Pediatric Oncology Cohort Study

Cancer Medicine, Volume 15, Issue 9, September 2026.
ABSTRACT Introduction Children treated with ifosfamide seem to have an increased risk for developing chronic kidney disease (CKD) already within the first years following chemotherapy. However, studies investigating CKD prevalence in this specific phase are scarce.
Lotte Pitlo, Francis S. P. L. Wens, Paulien A. M. A. Raymakers‐Janssen, Lianne M. Haveman, Johannes H. M. Merks, Martine van Grotel, Geert O. Janssens, Marta Fiocco, Marry M. van den Heuvel‐Eibrink, Gerrit van den Berg   +9 more
wiley   +1 more source

Biorelevant characterisation of amorphous furosemide salt exhibits conversion to a furosemide hydrate during dissolution

, 2013
Biorelevant dissolution behaviour of the amorphous sodium salt and amorphous acid forms of furosemide was evaluated, together with investigations of the solid state changes during in vitro dissolution in medium simulating the conditions in the small ...
Gordon, Sarah, Østergaard, Jesper, Pajander, Jari Pekka, Müllertz, Anette, Gordon, Sarah; id_orcid, Nielsen, Line Hagner, Rades, Thomas   +6 more
core   +1 more source

Cavernous Sinus Thrombosis Following the Use of Oral Contraceptive Pills in a Young Woman: A Case Report

Clinical Case Reports, Volume 14, Issue 9, September 2026.
ABSTRACT Cavernous sinus thrombosis (CST) is a rare and potentially life‐threatening subtype of cerebral venous sinus thrombosis that often poses diagnostic challenges in emergency settings. We report a 34‐year‐old woman with a one‐year history of oral contraceptive pill (OCP) use for polycystic ovary syndrome who presented with severe headache ...
Zohreh Akbari, Ali Salami, Ali Movahedi, Seyyedeh Maryam Seyyedy, Kiana Babaei   +4 more
wiley   +1 more source

Early Detection of Clinical Deterioration in ICU Patients With Respiratory Failure Receiving Vasoactive Support: A Machine Learning Approach to Identifying High‐Risk Individuals

Health Science Reports, Volume 9, Issue 9, September 2026.
ABSTRACT Background and Aims Acute respiratory failure requiring intensive care is frequently accompanied by hemodynamic instability, necessitating vasoactive pharmacologic support, and elevated mortality. We aimed to develop and validate a machine learning model to stratify all‐cause in‐hospital mortality risk in ICU patients with respiratory failure ...
Mohammad Fathi, Hamed Markazi Moghadam, Mahdis Fathi, Mohammadreza Hajiesmaeili, Navid Nooraei, Nasser Malekpour Alamdari, Sanaz Zargar Balaye Jame, Farhad Hashemnezhad Khataee, Nader Markazi Moghaddam   +8 more
wiley   +1 more source

Belzutifan‐Associated Reversible Heart Failure With Preserved Ejection Fraction in Metastatic Renal Cell Carcinoma

IJU Case Reports, Volume 9, Issue 5, September 2026.
ABSTRACT Background Belzutifan, a hypoxia‐inducible factor 2α (HIF‐2α) inhibitor, is effective for metastatic renal cell carcinoma (mRCC), although its cardiovascular safety profile remains unclear. Case Presentation A 52‐year‐old woman with mRCC developed progressive dyspnea and a 6.7‐kg weight gain 27 days after initiating belzutifan as third‐line ...
Hikaru Kimura, Shigeaki Nakazawa, Yu Ishizuya, Yoshiyuki Yamamoto, Kentaro Takezawa, Taigo Kato, Koji Hatano, Yoichi Kakuta, Atsunari Kawashima, Norio Nonomura   +9 more
wiley   +1 more source

Article Effect of furosemide and furosemide–carbazochrome combination on exercise-induced pulmonary hemorrhage in Standardbred racehorses

, 2009
— The objective was to quantify the effect of furosemide and carbazochrome on exercise-induced pul-monary hemorrhage (EIPH) in Standardbred horses using red blood cell count and hemoglobin concentration in bronchoalveolar lavage (BAL) fluid.
Cecilia I. Perez-moreno, Laurent L. Couëtil, Suzanne M. Pratt, Hugo G. Ochoa-acuña, Rose E. Raskin, Mark A. Russell   +5 more
core  

A Catalogue of Dispensation Lengths for Building Treatment Episodes—Application of the Waiting Time Distribution to All Commonly Prescribed Drugs in Denmark

Pharmacoepidemiology and Drug Safety, Volume 35, Issue 9, September 2026.
ABSTRACT Background In pharmacoepidemiologic research, correct assignment of the length of single dispensation is critical to build treatment episodes. The parametric reverse waiting time distribution (rWTD) is a particularly attractive data‐driven method to estimate dispensation lengths.
Mette Reilev, Lotte Rasmussen, Jonas Kanstrup Olsen, Martin Thomsen Ernst, Saad Hanif Abbasi, Rikke Wesselhoeft, Mette Bliddal, Jesper Hallas, Henrik Støvring   +8 more
wiley   +1 more source

Net Renal Drug Secretion Critically Requires Significant Contribution of Basal Uptake Transporters: Perspective From Mechanistic Kidney Model Simulation and Integration of Clinical and In Vitro Data

CPT: Pharmacometrics &Systems Pharmacology, Volume 15, Issue 9, September 2026.
ABSTRACT Renal clearance (CLr) is the net outcome of glomerular filtration, secretion, and reabsorption, which makes the quantitative requirements for net renal secretion difficult to infer from simple clearance models. Using a mechanistic kidney model (MechKiM), we simulated blood‐referenced CLr (CLr,b) for 30,000 virtual drugs (neutral, monoanionic ...
Toshiaki Tsuchitani, Masatoshi Tomi, Yuichi Sugiyama   +2 more
wiley   +1 more source

Phenotyping Preeclampsia Using Unsupervised Machine Learning: A Prospective Cohort Study

BJOG: An International Journal of Obstetrics &Gynaecology, Volume 133, Issue 10, Page 1926-1936, September 2026.
ABSTRACT Objective To explore clinically meaningful phenotypes of preeclampsia using unsupervised machine learning. Design Prospective cohort study. Setting BCNatal, a tertiary maternal‐foetal medicine centre (Barcelona, Spain). Population A total of 482 pregnant women diagnosed with preeclampsia between August 2013 and April 2024.
Ohad Houri, Lina Youssef, Francesca Crovetto, Maria Borrell, Maddalena Crimella, Maria Giulia Ferrante, Rommy H. Novoa, Irene Casas, Noelia Encabo, Leticia Benitez, Marta Larroya, Anna Peguero, Eva Meler, Sara Castro‐Barquero, Bart Bijnens, Francesc Figueras, Eduard Gratacos, Gabriel Bernardino, Fàtima Crispi   +18 more
wiley   +1 more source