Real World Experience in Effect of Torsemide vs. Furosemide After Discharge in Patients with HFpEF [PDF]
ESC Heart FailureAims Few studies have focused on the effect of torsemide versus furosemide after discharge on prognosis in patients with heart failure with preserved ejection fraction (HFpEF).
Danyan Xu
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Pharmaceutics, 2022 Torsemide is a diuretic drug used for several cardiovascular and chronic diseases. With regard to the clinical application of torsemide, studies on individualized pharmacotherapy and modeling that take variability in pharmacokinetics (PKs) within a ...
Yong-Bok Lee +2 more
exaly +4 more sources
Pharmaceutical Technology in Hospital Pharmacy, 2018 A simple, highly robust (quality by design (QbD) approach), precise and accurate method using high performance liquid chromatography coupled to mass spectrometry has been established for the simultaneous separation, identification and quantitation of a ...
Prajesh Prajapati, Y K Agrawal
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Efficacy of torsemide versus furosemide in heart failure: a systematic review and meta-analysis of randomized controlled trials [PDF]
Archives of Medical Science: Atherosclerotic DiseasesIntroduction Loop diuretics are a cornerstone in the symptomatic management of heart failure. There is conflicting evidence regarding potential differences between torsemide and furosemide in their effects on heart failure outcomes.
Mohamed Magdi Eid +9 more
doaj +2 more sources
Comparative analysis of furosemide and torsemide efficacy in 24 hours of acute heart failure admission [PDF]
Frontiers in PharmacologyBackgroundIntravenous (IV) furosemide and torsemide represent a cornerstone of guideline-directed medical therapy for acute heart failure (AHF). However, the evidence regarding the superiority of each agent remains controversial.MethodsThe prospective ...
Małgorzata Małek-Elikowska +5 more
doaj +2 more sources
Real-world effectiveness and safety of torsemide and spironolactone fixed dose combination in Indian heart failure patients (RESTORE-HF study): a prospective, multicenter, observational study [PDF]
Therapeutic Advances in Cardiovascular DiseaseBackground: Heart failure (HF) remains a major public health challenge in India, with a need for effective and well-tolerated therapeutic strategies.
Chandrashekhar K. Ponde +9 more
doaj +2 more sources
Structural basis for human NKCC1 inhibition by loop diuretic drugs [PDF]
The EMBO JournalNa+–K+–Cl− cotransporters functions as an anion importers, regulating trans-epithelial chloride secretion, cell volume, and renal salt reabsorption. Loop diuretics, including furosemide, bumetanide, and torsemide, antagonize both NKCC1 and NKCC2, and are
Yongxiang Zhao +6 more
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Mechanistic Differences between Torsemide and Furosemide. [PDF]
J Am Soc NephrolKey Points Oral torsemide was not superior to furosemide in measures of renal tubular delivery or duration of action.A dose equivalence of approximately 40 mg oral furosemide:10 mg oral torsemide resulted in similar natriuresis.The two-fold higher doses of torsemide did not improve fluid status
Rao VS +19 more
europepmc +3 more sources
TRANSFORM-HF Trial: Choice of loop diuretic in acute heart failure does not matter! [PDF]
Journal of Family Medicine and Primary CareThe major clinical manifestations of heart failure (HF) are due to fluid retention and congestion, and thus, therapy targeting congestion plays a central role in HF management. Furosemide is by far the most commonly prescribed loop diuretic.
Akshyaya Pradhan +2 more
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A case of bullous pemphigoid induced by torsemide
JAAD Case Reports, 2022 Paul Wurtz, BS +2 more
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