Real World Experience in Effect of Torsemide vs. Furosemide After Discharge in Patients with HFpEF [PDF]
ESC Heart FailureAims Few studies have focused on the effect of torsemide versus furosemide after discharge on prognosis in patients with heart failure with preserved ejection fraction (HFpEF).
Jinping Si, Danyan Xu
exaly +6 more sources
Population Pharmacokinetic (Pop-PK) Analysis of Torsemide in Healthy Korean Males Considering CYP2C9 and OATP1B1 Genetic Polymorphisms [PDF]
Pharmaceutics, 2022 Torsemide is a diuretic drug used for several cardiovascular and chronic diseases. With regard to the clinical application of torsemide, studies on individualized pharmacotherapy and modeling that take variability in pharmacokinetics (PKs) within a ...
Seung-Hyun Jeong +2 more
exaly +5 more sources
Journal of Advanced Research, 2015 Comparative study of cardio protective effect of aliskiren, telmisartan, and torsemide was carried out on l-nitro arginine methyl ester (l-NAME) induced hypertension in rats. The three drugs were given daily for 8 weeks simultaneously with l-NAME, with a
Eman S Said
exaly +5 more sources
Pharmaceutics, 2022 Torsemide is a widely used diuretic in clinical practice. In this study, pharmacokinetic (PK) and pharmacodynamic (PD) simulations of torsemide for various population groups and exposure scenarios were performed through human-scale physiologically-based ...
Seung-Hyun Jeong +2 more
exaly +4 more sources
Evaluation of the short‐term echocardiographic effects of two loop diuretics, furosemide and torsemide, in a group of dogs [PDF]
Veterinary Medicine and Science, 2023 Background Two loop diuretics, torsemide and frusemide, can affect the urinary system and consequently the cardiordiovascular haemodynamics in different ways.
Peter B Hill, Morteza Hosseininejad
exaly +3 more sources
Development and validation of stability-indicating methods for determination of torsemide
Bulletin of the Chemical Society of Ethiopia, 2016 Four sensitive and precise methods for determination of torsemide in presence of its degradation product and in pharmaceutical formulation were developed and validated.
H. E. Zaazaa +3 more
doaj +4 more sources
Comparative analysis of furosemide and torsemide efficacy in 24 hours of acute heart failure admission [PDF]
Frontiers in PharmacologyBackgroundIntravenous (IV) furosemide and torsemide represent a cornerstone of guideline-directed medical therapy for acute heart failure (AHF). However, the evidence regarding the superiority of each agent remains controversial.MethodsThe prospective ...
Małgorzata Małek-Elikowska +5 more
doaj +2 more sources
Efficacy of torsemide versus furosemide in heart failure: a systematic review and meta-analysis of randomized controlled trials [PDF]
Archives of Medical Science: Atherosclerotic DiseasesIntroduction Loop diuretics are a cornerstone in the symptomatic management of heart failure. There is conflicting evidence regarding potential differences between torsemide and furosemide in their effects on heart failure outcomes.
Mohamed Magdi Eid +9 more
doaj +2 more sources
Heritability of metoprolol and torsemide pharmacokinetics
Clinical Pharmacology & Therapeutics, 2015 Genetic variation in the pharmacokinetics of metoprolol and torsemide due to polymorphisms in CYP2D6, CYP2C9, and OATP1B1 has been extensively studied.
Hofmann, U. G. +27 more
core +4 more sources
Brazilian Journal of Pharmaceutical Sciences, 2022 A simple, precise, accurate and robust high performance liquid chromatographic method has been developed for simultaneous estimation of Torsemide and Eplerenone in tablet dosage form.
Madhuri Ajay Hinge, Dipti Patel
doaj +3 more sources