Exploring Risks of Adverse Drug Events From Single Drug to Three-Drug Combination. [PDF]
ABSTRACT Use of three‐drug combinations is common and could increase the risk of adverse drug events (ADEs). Signals of ADEs from three‐drug combinations could be identified from real‐world data, and the risks of ADEs from single drug exposure to three‐drug combination exposure could be illustrated by a graphic model.
Shi Y +14 more
europepmc +2 more sources
"Loop Diuretics in Severe Aortic Stenosis: A Marker of Disease Severity, Not a Mortality Driver". [PDF]
Clinical Cardiology, Volume 49, Issue 4, April 2026.
Tahir I, Shahbaz H.
europepmc +2 more sources
Pushing Limits: Exploring Torsemide\u27s Potential Through In-Vitro Mucoadhesive Buccal Delivery Characterization [PDF]
This study focuses on developing and evaluating mucoadhesive buccal tablets containing Torsemide, utilizing HPMC K-100, Xanthan Gum, and chitosan polymers at varying concentrations.
Mahalingan, K. +4 more
core +1 more source
Spontaneous Reduction in Mitral Valve Regurgitation in Three Dogs With Severe Myxomatous Mitral Valve Disease: An Unusual Case Report. [PDF]
In dogs with MMVD, severe valvular degeneration with chordae tendineae rupture is generally associated with a poor prognosis despite medical management. These three cases demonstrate spontaneous reduction in mitral regurgitation accompanied by decreased coaptation gap, reduced regurgitant volume, reverse cardiac remodelling, discontinuation of ...
Nam HS, Oh Y.
europepmc +2 more sources
Diuretic resistance and the role of albumin in congestive heart failure
Diuresis with loop diuretics is the mainstay treatment for volume optimization in patients with congestive heart failure, in which perfusion and volume expansion play a crucial role.
Carol Fernandez Hazim +6 more
doaj +1 more source
Background: Chronic kidney disease affects the structure and function of the kidneys over a specific period of time. It is a worldwide public health related problem.
Nabin Kumar Yadav +2 more
doaj +1 more source
Third Trimester Lower Extremity Lymphorrhea
Introduction. Lower extremity edema is one of the most common complaints among pregnant patients. However, there is no literature mentioning weeping edema (i.e., lymphorrhea) in a pregnant woman who has no concordant underlying renal and/or cardiac ...
Kaori Morimoto, Luke O’Rourke
doaj +1 more source
Too Much Stress- A Rare Case of Takotsubo Cardiomyopathy [PDF]
Takotsubo syndrome is a reversible, stress-induced transient systolic and diastolic dysfunction. It was first described as a characteristic ballooning of left ventricular apex which closely resembles a Japanese fishing pot.
Oorya Narayanan Balasubramani +1 more
doaj +1 more source
A Comparative Evaluation of Ramipril as Monotherapy and Combination of Ramipril with Torsemide in Hypertension [PDF]
Introduction: A Fixed-Dose Combination (FDC) of antihypertensive agents of different groups might offer advantages of efficacy, tolerability and compliance over monotherapy.
Navjot Kaur +6 more
doaj +1 more source
Background Loop diuretics are recommended by clinical practice guidelines to treat volume overload in acute decompensated heart failure (ADHF). The effectiveness of switching furosemide to torsemide versus optimizing the furosemide dose following ADHF ...
Alaa Rahhal +5 more
doaj +1 more source

