Comparative Effectiveness of Torsemide Versus Furosemide in Heart Failure Patients: Insights From the Protect Trial [PDF]
Future Cardiology, 2015 The authors assessed the comparative effectiveness of torsemide versus furosemide in the PROTECT ...
Robert J Mentz +2 more
exaly +2 more sources
Structural basis for human NKCC1 inhibition by loop diuretic drugs [PDF]
The EMBO JournalNa+–K+–Cl− cotransporters functions as an anion importers, regulating trans-epithelial chloride secretion, cell volume, and renal salt reabsorption. Loop diuretics, including furosemide, bumetanide, and torsemide, antagonize both NKCC1 and NKCC2, and are
Yongxiang Zhao +6 more
doaj +2 more sources
Torsemide versus furosemide in heart failure patients: insights from Duke University Hospital.
, 2015 Furosemide has historically been the primary loop diuretic in heart failure patients despite data suggesting potential advantages with torsemide. We used the Duke Echocardiography Lab Database to investigate patients admitted with heart failure to Duke ...
Anstrom, Kevin J +9 more
core +3 more sources
Development and evaluation of a chronotherapeutic drug delivery system of torsemide [PDF]
Brazilian Journal of Pharmaceutical Sciences, 2011 The objective of this study was to prepare and evaluate chronotherapeutic drug delivery systems (ChrDDs) of torsemide. Compression coated tablets (CCT) containing torsemide in the core tablet were prepared by the compression coating technique with ...
Songa Ambedkar Sunil +5 more
doaj +2 more sources
TRANSFORM-HF Trial: Choice of loop diuretic in acute heart failure does not matter! [PDF]
Journal of Family Medicine and Primary CareThe major clinical manifestations of heart failure (HF) are due to fluid retention and congestion, and thus, therapy targeting congestion plays a central role in HF management. Furosemide is by far the most commonly prescribed loop diuretic.
Akshyaya Pradhan +2 more
doaj +2 more sources
Mechanistic Differences between Torsemide and Furosemide. [PDF]
J Am Soc NephrolKey Points Oral torsemide was not superior to furosemide in measures of renal tubular delivery or duration of action.A dose equivalence of approximately 40 mg oral furosemide:10 mg oral torsemide resulted in similar natriuresis.The two-fold higher doses of torsemide did not improve fluid status
Rao VS +19 more
europepmc +3 more sources
Simple Spectrophotometric Determination of Torsemide in Bulk Drug and in Formulations [PDF]
E-Journal of Chemistry, 2008 A simple and cost effective spectrophotometric method is described for the determination of torsemide in pure form and in pharmaceutical formulations.
Marothu Vamsi Krishna +1 more
doaj +2 more sources
Third Trimester Lower Extremity Lymphorrhea
Case Reports in Obstetrics and Gynecology, 2021 Introduction. Lower extremity edema is one of the most common complaints among pregnant patients. However, there is no literature mentioning weeping edema (i.e., lymphorrhea) in a pregnant woman who has no concordant underlying renal and/or cardiac ...
Kaori Morimoto, Luke O’Rourke
doaj +2 more sources
Photosensitive Lichenoid Reaction to Torsemide-a Loop Diuretic [PDF]
Mayo Clinic Proceedings, 1997 Torsemide, a potent loop diuretic of the sulfonylurea class, has been available for clinical use in the United States since 1993. Adverse generalized and cutaneous reactions to this medication are uncommon and are usually mild and transient. In this article, we describe an 82-year-old man who had a photosensitive lichenoid reaction due to torsemide ...
D R, Byrd, I, Ahmed
openaire +3 more sources
BIOAVAILABILITY, PHARMACOKINETICS, AND PHARMACODYNAMICS OF TORSEMIDE IN PATIENTS WITH CIRRHOSIS
Clinical Pharmacology and Therapeutics, 1993 The bioavailability, pharmacokinetics, and pharmacodynamics of torsemide (10 mg orally and intravenously) were determined in a randomized crossover clinical trial with 12 patients with ascites caused by cirrhosis.
POUND, D +5 more
core +3 more sources