Heritability of metoprolol and torsemide pharmacokinetics
Genetic variation in the pharmacokinetics of metoprolol and torsemide due to polymorphisms in CYP2D6, CYP2C9, and OATP1B1 has been extensively studied. However, it is still unknown how much of the variation in pharmacokinetics of these two clinically important drugs in total is due to genetic factors.
Matthaei, Johannes +10 more
exaly +5 more sources
Clinical evaluation of a novel fixed-dose combination tablet (Sentorpil® ForteGold) versus compounded powdered medications in dogs with myxomatous mitral valve disease: a randomized, double-blind study [PDF]
IntroductionMyxomatous mitral valve disease (MMVD) is a prevalent cardiac condition in older, small-breed dogs, often managed with multiple medications.
Jiyoung Park +3 more
doaj +2 more sources
"Loop Diuretics in Severe Aortic Stenosis: A Marker of Disease Severity, Not a Mortality Driver". [PDF]
Clinical Cardiology, Volume 49, Issue 4, April 2026.
Tahir I, Shahbaz H.
europepmc +2 more sources
A case of bullous pemphigoid induced by torsemide
Paul Wurtz, BS +2 more
doaj +3 more sources
A retrospective study of 14 dogs with advanced heart failure treated with loop diuretics and hydrochlorothiazide [PDF]
Background: The use of thiazide diuretics is recommended in the American College of Veterinary Internal Medicine guidelines for advanced heart failure due to mitral insufficiency (MI) in dogs.
Koji Iwanaga +2 more
doaj +1 more source
Background Two loop diuretics, torsemide and frusemide, can affect the urinary system and consequently the cardiordiovascular haemodynamics in different ways.
Farzaneh Hosseini +3 more
doaj +1 more source
Overview of Diuretic Strategies in Edematous States [PDF]
Considering potential physiologic causes of volume overload in clinical practice, such as heart failure, renal failure, nephrotic syndrome, or portal hypertension, may yield insight into directing therapy beyond switching from oral to intravenous ...
Mahajan, MD, Kedar
core +4 more sources
Comparing Torsemide with Furosemide: Finally a Mechanistic Approach that Says, "Enough Already". [PDF]
Al-Awqati Q.
europepmc +3 more sources
Diuretic resistance and the role of albumin in congestive heart failure
Diuresis with loop diuretics is the mainstay treatment for volume optimization in patients with congestive heart failure, in which perfusion and volume expansion play a crucial role.
Carol Fernandez Hazim +6 more
doaj +1 more source
Background: Chronic kidney disease affects the structure and function of the kidneys over a specific period of time. It is a worldwide public health related problem.
Nabin Kumar Yadav +2 more
doaj +1 more source

