Results 11 to 20 of about 2,199 (188)
Torsemide is a widely used diuretic in clinical practice. In this study, pharmacokinetic (PK) and pharmacodynamic (PD) simulations of torsemide for various population groups and exposure scenarios were performed through human-scale physiologically-based ...
Seung-Hyun Jeong +2 more
doaj +2 more sources
Heritability of metoprolol and torsemide pharmacokinetics
Genetic variation in the pharmacokinetics of metoprolol and torsemide due to polymorphisms in CYP2D6, CYP2C9, and OATP1B1 has been extensively studied. However, it is still unknown how much of the variation in pharmacokinetics of these two clinically important drugs in total is due to genetic factors.
Matthaei, Johannes +10 more
openaire +4 more sources
Development and validation of stability-indicating methods for determination of torsemide [PDF]
Four sensitive and precise methods for determination of torsemide in presence of its degradation product and in pharmaceutical formulation were developed and validated.
H. E. Zaazaa +3 more
doaj +2 more sources
A simple, precise, accurate and robust high performance liquid chromatographic method has been developed for simultaneous estimation of Torsemide and Eplerenone in tablet dosage form.
Madhuri Ajay Hinge, Dipti Patel
doaj +3 more sources
Effect of aliskiren, telmisartan and torsemide on cardiac dysfunction in l-nitro arginine methyl ester (l-NAME) induced hypertension in rats [PDF]
Comparative study of cardio protective effect of aliskiren, telmisartan, and torsemide was carried out on l-nitro arginine methyl ester (l-NAME) induced hypertension in rats. The three drugs were given daily for 8 weeks simultaneously with l-NAME, with a
Sawsan A. Sadek +3 more
doaj +2 more sources
Development and evaluation of a chronotherapeutic drug delivery system of torsemide [PDF]
The objective of this study was to prepare and evaluate chronotherapeutic drug delivery systems (ChrDDs) of torsemide. Compression coated tablets (CCT) containing torsemide in the core tablet were prepared by the compression coating technique with ...
Songa Ambedkar Sunil +5 more
doaj +2 more sources
Simple Spectrophotometric Determination of Torsemide in Bulk Drug and in Formulations [PDF]
A simple and cost effective spectrophotometric method is described for the determination of torsemide in pure form and in pharmaceutical formulations.
Marothu Vamsi Krishna +1 more
doaj +2 more sources
Preparation And Characterisation Of Torsemide Microcapsules
Hypertension (HTN or HT), also known as high blood pressure (HBP), is a long term medical condition in which the blood pressure in the arteries is persistently elevated. Microencapsulation is a process of applying relatively thin coatings to small particles of solids or droplets of liquids and dispersions. It provides the means of converting liquids to
Mitta Chaitanya*and Dr. P. Narayana Raju
openaire +2 more sources
Exploring Risks of Adverse Drug Events From Single Drug to Three-Drug Combination. [PDF]
ABSTRACT Use of three‐drug combinations is common and could increase the risk of adverse drug events (ADEs). Signals of ADEs from three‐drug combinations could be identified from real‐world data, and the risks of ADEs from single drug exposure to three‐drug combination exposure could be illustrated by a graphic model.
Shi Y +14 more
europepmc +2 more sources
"Loop Diuretics in Severe Aortic Stenosis: A Marker of Disease Severity, Not a Mortality Driver". [PDF]
Clinical Cardiology, Volume 49, Issue 4, April 2026.
Tahir I, Shahbaz H.
europepmc +2 more sources

