Results 131 to 140 of about 76,034 (305)
Physiologically Based Pharmacokinetic Models of Probenecid and Furosemide to Predict Transporter Mediated Drug-Drug Interactions [PDF]
Hannah Britz +8 more
openalex +1 more source
Abstract The principal processes that govern interstitial K+ ([K+]o) buffering in mouse optic nerve (MON), a central white matter tract, either directly consume energy (Na+–K+‐ATPase) or use transmembrane ion gradients created by energy‐dependent pumps to enable the K+ fluxes that maintain a stable [K+]o, and thus ready availability of utilisable ...
Amy J. Hopper, Angus M. Brown
wiley +1 more source
ABSTRACT Endoscopic submucosal dissection (ESD) is widely used for early esophageal cancer, even in patients with liver cirrhosis (LC). Corticosteroids, administered orally or by local injection, are often used to prevent post‐ESD esophageal stricture. However, their safety in patients with decompensated LC and refractory ascites remains unclear. A man
Yuki Tamura +9 more
wiley +1 more source
Furosemide Treatment, Angiotensin II, and Renal Growth and Development in the Rat [PDF]
Pascale H. Lane
openalex +1 more source
Machine learning methods for predicting adverse drug events: A systematic review
Abstract Predicting adverse drug events (ADEs) in outpatient settings is crucial for improving medication safety, identifying high‐risk patients and reducing health‐care costs. While traditional methods struggle with the complexity of health‐care data, machine learning (ML) models offer improved prediction capabilities; however, their effectiveness in ...
Niaz Chalabianloo +8 more
wiley +1 more source
A Case of Drug‐Induced Pancreatitis
ABSTRACT Drug‐induced pancreatitis (DIP) is a rare but important cause of acute abdominal pain, and ciprofloxacin‐associated cases are exceptionally uncommon. We report a 35‐year‐old woman with no significant medical history who developed severe epigastric pain radiating to the back, accompanied by nausea and vomiting, 3 days after initiating self ...
Muskan Shrestha +5 more
wiley +1 more source
Physiology Based Pharmacokinetic (PBPK) modeling is an established essential tool for predicting and/or analyzing drug–drug interactions (DDI). Uncertainty and variability associated with in vitro determined DDI‐related parameters have often been considered a limitation for predicting PBPK‐DDIs.
Kunal S. Taskar +2 more
wiley +1 more source
Urinary Kallikrein in normotensive Subjects and in Patients with Essential Hypertension [PDF]
Distler, A. +7 more
core +1 more source
Resistant arterial hypertension in a patient with adrenal incidentaloma multiple steno-obstructive vascular lesions and antiphospholipid syndrome [PDF]
Resistant hypertension is defined as above of blood pressure (≤ 140/90 mmHg) despite therapy with three or more antihypertensive drugs of different classes at maximum tolerable doses with one bling a diuretic.
CONCISTRE, ANTONIO +8 more
core
Effects of furosemide on renal haemodynamics and proximal tubular sodium reabsorption in conscious rats [PDF]
Sten Christensen, Jørgen S. Petersen
openalex +1 more source

