Results 71 to 80 of about 1,247,959 (250)
PICALM::MLLT10 translocated leukemia
FEBS Letters, EarlyView.This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen +7 more
wiley +1 more source
Modelos de representación de imprecisión e incertidumbre en fusión de alto nivel [PDF]
, 2014 Actas de: XVII Congreso Español sobre Tecnologías y Lógica Fuzzy (ESTYLF 2014). Zaragoza, 5-7 de febrero de 2014.Las técnicas de fusión de datos e información procedente de redes de sensores necesitan manejar información incierta e imprecisa, puesto que ...
García, Jesús +2 more
core +2 more sources
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
An improved P-wave velocity reference model for Costa Rica
Geofísica Internacional, 2001 Derivamos un modelo de velocidad unidimensional para la onda P en Costa Rica, el cual puede servir en la rutina de localización de eventos sísmicos y como modelo de referencia para tomografía en 3 dimensiones.
Ronnie Quintero, Edi Kissling
doaj +1 more source
The life cycles of cryptogams [PDF]
, 1991 Meiosis and karyogamy are recognized as control points in the life cycle of cryptogams. The control of meiosis is evidently complex and in yeast, and by analogy in all cryptogams, involves progressive gene activation.
Bell, Peter R.
core +2 more sources
Molecular Oncology, EarlyView.A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath +13 more
wiley +1 more source
El proceso de evaluación previa en las fusiones y adquisiciones empresariales en el Perú
Quipukamayoc, 2018 La investigación recoge las percepciones sobre el proceso de evaluación previa en las fusiones y adquisiciones empresariales en el Perú respecto de la posibilidad de optimizar este proceso, tendiente a fortalecer los mercados de capitales y de valores ...
Cleofé Maritza Verástegui Corrales +2 more
doaj +1 more source
Don Benito-Villanueva de la Serena (un caso de conurbación en Extremadura) [PDF]
, 1981 Es frecuente, en el mapa de ciudades del mundo, la existencia de núcleos próximos. Tanto que a veces es difícil señalar en el espacio el alcance, límites o influencias de cada uno de ellos. La aglomeración implica primacía, mientras que la conurbación se
Barrientos Alfageme, Gonzalo
core +1 more source
YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma
Molecular Oncology, EarlyView.The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy +9 more
wiley +1 more source