Results 61 to 70 of about 2,798,576 (374)
α2 → 8 polysialic acid elicits poor immunogenicity. Small‐angle scattering shows a supramolecular structure with parallel‐chain binding, although in different forms at μm and mm calcium. The major histocompatibility complex requires molecular weights around 2000 Da to produce antibodies, and 2000 Da polysialic oligomers will bind in these structures ...
Kenneth A. Rubinson
wiley +1 more source
Track Segment Association via track graph representation learning
Traditional Track Segment Association (TSA) methods used track position vectors or other track information to get association results. However, simply extracting the track position information to form track vectors will lead to the loss of irregular ...
Wei Xiong+5 more
doaj +1 more source
Fusion peptides and the mechanism of viral fusion
Segments of viral fusion proteins play an important role in viral fusion. They are defined by a number of criteria, including the sensitivity of this region of the viral fusion protein to loss of function as a consequence of mutation. In addition, small model peptides designed to mimic this segment of viral fusion proteins often have some membrane ...
openaire +3 more sources
Disruption of fusion results in mitochondrial heterogeneity and dysfunction [PDF]
Mitochondria undergo continual cycles of fusion and fission, and the balance of these opposing processes regulates mitochondrial morphology. Paradoxically, cells invest many resources to maintain tubular mitochondrial morphology, when reducing both ...
Chan, David C.+2 more
core +1 more source
Venom peptides have shown promise in treating pain. Our study uses computer screening to identify a peptide that targets a sodium channel (NaV1.7) linked to chronic pain. We produced the peptide in the laboratory and refined its design, advancing the search for innovative pain therapies.
Gagan Sharma+8 more
wiley +1 more source
The power of microRNA regulation—insights into immunity and metabolism
MicroRNAs are emerging as crucial regulators at the intersection of metabolism and immunity. This review examines how miRNAs coordinate glucose and lipid metabolism while simultaneously modulating T‐cell development and immune responses. Moreover, it highlights how cutting‐edge artificial intelligence applications can identify miRNA biomarkers ...
Stefania Oliveto+2 more
wiley +1 more source
Objectives: Understand that soil is composed of inorganic and organic solid material, water, and air.·Investigate the properties of the inorganic solid components of soil: sand, silt, and clay. Recognize that varying proportions of sand, silt, and clay
IMSA Fusion
core +1 more source
Identification of novel small molecule inhibitors of ETS transcription factors
ETS transcription factors play an essential role in tumourigenesis and are indispensable for sprouting angiogenesis, a hallmark of cancer, which fuels tumour expansion and dissemination. Thus, targeting ETS transcription factor function could represent an effective, multifaceted strategy to block tumour growth. The evolutionarily conserved E‐Twenty‐Six
Shaima Abdalla+9 more
wiley +1 more source
Multi-Sensor Data and Knowledge Fusion -- A Proposal for a Terminology Definition [PDF]
Fusion is a common tool for the analysis and utilization of available datasets and so an essential part of data mining and machine learning processes. However, a clear definition of the type of fusion is not always provided due to inconsistent literature.
arxiv
Active Supercontinuum Injection for Optical Parametric Chirped Pulse Amplification
The anticipant supercontinuum is a prerequisite for the pump seed generation in an optical parametric chirped pulse amplification (OPCPA) system. To achieve the anticipant supercontinuum, we develop an active method operated in a two-level control scheme
Jie Mu+11 more
doaj +1 more source