Results 41 to 50 of about 535,764 (342)

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

Design and system application of risk evaluation model for mining roadway stability

Meikuang Anquan
For the problem that the potential risk of coal mine roadway is difficult to be quantified and predicted, the risk factors affecting the stability of roadway are screened and extracted.
Qingshui MA, Xiangzheng ZHAO, Zhenqi SONG, Yuhu YANG   +3 more
doaj   +1 more source

Two-Layer Nonlinear FIR Filter and Unscented Kalman Filter Fusion With Application to Mobile Robot Localization

IEEE Access, 2020
In this paper, we propose a new state estimator called the two-layer nonlinear finite impulse response (TLNF) filter and adopt this new filter and unscented Kalman filter (UKF) as subfilters to create the fusion TLNF/UK filter.
Young Eun Kim, Hyun Ho Kang, Choon Ki Ahn   +2 more
doaj   +1 more source

Fusion of irreducible modules in WLM(p,p')

, 2009
Based on symmetry principles, we derive a fusion algebra generated from repeated fusions of the irreducible modules appearing in the W-extended logarithmic minimal model WLM(p,p').
Rasmussen, Jorgen
core   +1 more source

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

Molecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic, Anne Nørremølle, Lilian Bomme Ousager, Lars van Brakel Andersen, Marie Louise Mølgaard Binderup, Mads Thomassen   +5 more
wiley   +1 more source

A Voronoi–A* Fusion Algorithm with Adaptive Layering for Efficient UAV Path Planning in Complex Terrain

Drones
Unmanned Aerial Vehicles (UAVs) face significant challenges in global path planning within complex terrains, as traditional algorithms (e.g., A*, PSO, APF) struggle to balance computational efficiency, path optimality, and safety.
Boyu Dong, Gong Zhang, Yan Yang, Peiyuan Yuan, Shuntong Lu   +4 more
doaj   +1 more source

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

Molecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak, Iva Staniczková Zambo, Matěj Přikryl, Peter Múdry, Danica Zapletalová, Jarmila Navrátilová, Jiří Navrátil, Jan Šmarda, Liudmyla Drobot, Petr Beneš, Lucia Knopfová   +10 more
wiley   +1 more source

Research on APF-Dijkstra Path Planning Fusion Algorithm Based on Steering Model and Volume Constraints

Algorithms
For the local oscillation phenomenon of the APF algorithm in the face of static U-shaped obstacles, the path cusp phenomenon caused by the vehicle corner and path curvature constraints is not taken into account, as well as the low path safety caused by ...
Xizheng Wang, Gang Li, Zijian Bian
doaj   +1 more source

Reliable fusion of ToF and stereo depth driven by confidence measures [PDF]

, 2016
In this paper we propose a framework for the fusion of depth data produced by a Time-of-Flight (ToF) camera and stereo vision system. Initially, depth data acquired by the ToF camera are upsampled by an ad-hoc algorithm based on image segmentation and ...
Marin, Giulio, Mattoccia, Stefano, Zanuttigh, Pietro   +2 more
core   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source