Results 71 to 80 of about 87,221 (254)

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

FEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill, Yelyzaveta Pulnova, Elke De Zitter, Helen M. Ginn, Briony A. Yorke   +4 more
wiley   +1 more source

YIPFα1A expression is regulated by multilayered molecular mechanisms

FEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji, Yurika Nakanishi, Nobuhiro Nakamura   +2 more
wiley   +1 more source

Multi-Level Feature Fusion in CNN-Based Human Action Recognition: A Case Study on EfficientNet-B7

Journal of Imaging
Accurate human action recognition is becoming increasingly important across various fields, including healthcare and self-driving cars. A simple approach to enhance model performance is incorporating additional data modalities, such as depth frames ...
Pitiwat Lueangwitchajaroen, Sitapa Watcharapinchai, Worawit Tepsan, Sorn Sooksatra   +3 more
doaj   +1 more source

Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

FEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee, Giulia Zanetti, Bram van den Broek, Kees Jalink   +3 more
wiley   +1 more source

Exponential Fusion of Interpolated Frames Network (EFIF-Net): Advancing Multi-Frame Image Super-Resolution with Convolutional Neural Networks

Sensors
Convolutional neural networks (CNNs) have become instrumental in advancing multi-frame image super-resolution (SR), a technique that merges multiple low-resolution images of the same scene into a high-resolution image.
Hamed Elwarfalli, Dylan Flaute, Russell C. Hardie   +2 more
doaj   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

Fusion frame constructions and frame partitions [PDF]

, 2018
Fusion frames consist of a sequence of subspaces from a Hilbert space and corresponding positive weights so that the sum of weighted orthogonal projections onto these subspaces is an invertible operator on the space. Despite extensive literature on fusion frames, and several construction methods for unit-weight fusion frames with prescribed subspace ...
openaire   +2 more sources

The crystal structure of the Borrelia burgdorferi nicotinamidase BBE22 resolves a long‐standing annotation error

FEBS Open Bio, EarlyView.
The crystal structure of Borrelia burgdorferi nicotinamidase (PncA/BBE22) reveals the correct full‐length protein initiated from a non‐canonical AUU start codon. The structure validates previous biochemical findings and resolves a long‐standing annotation error, demonstrating that the truncated database sequence is structurally incompatible with the ...
Kalvis Brangulis
wiley   +1 more source

Scene Text Detection Based on Multi-scale Feature Extraction and Bidirectional Feature Fusion

Journal of Harbin University of Science and Technology
Natural scene text detection is a fundamental research work in the field of image processing and has a wide range of applications. Currently, natural scene text detection usually adopts single-scale convolution and multi-scale feature fusion to ...
LIAN Zhe, YIN Yanjun, ZHI Min, XU Qiaozhi   +3 more
doaj   +1 more source

Allogenic Stem Cells in Spinal Fusion: A Systematic Review

Global Spine Journal, 2019
Study Design: Systematic review. Objectives: To review, critically appraise, and synthesize evidence on the use of allogenic stem cell products for spine fusion compared with other bone graft materials.
Patrick C. Hsieh MD, Zorica Buser PhD, Andrea C. Skelly PhD, Erika D. Brodt, Darrel Brodke MD, Hans-Joerg Meisel MD, PhD, Jong-Beom Park MD, S. Tim Yoon MD, PhD, Jeffrey C. Wang MD   +8 more
doaj   +1 more source