Results 141 to 150 of about 1,121,449 (385)
Molecular Oncology, EarlyView.Urine is a rich source of biomarkers for cancer detection. Tumor‐derived material is released into the bloodstream and transported to the urine. Urine can easily be collected from individuals, allowing non‐invasive cancer detection. This review discusses the rationale behind urine‐based cancer detection and its potential for cancer diagnostics ...
Birgit M. M. Wever +1 more
wiley +1 more source
mBioInfection with respiratory syncytial virus (RSV) is a major cause of acute lower respiratory tract disease in young children and older people. Despite intensive efforts over the past few decades, no direct-acting small-molecule agents against RSV are ...
Qiaoyun Song +15 more
doaj +1 more source
Breaking In: Human Metapneumovirus Fusion and Entry
Viruses, 2013 Human metapneumovirus (HMPV) is a leading cause of respiratory infection that causes upper airway and severe lower respiratory tract infections. HMPV infection is initiated by viral surface glycoproteins that attach to cellular receptors and mediate ...
John V. Williams, Reagan G. Cox
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Bidirectional Hierarchical Protein Multi-Modal Representation Learning [PDF]
arXivProtein representation learning is critical for numerous biological tasks. Recently, large transformer-based protein language models (pLMs) pretrained on large scale protein sequences have demonstrated significant success in sequence-based tasks. However, pLMs lack structural information. Conversely, graph neural networks (GNNs) designed to leverage 3D
arxiv
Retention of purified proteins in resealed human erythrocyte ghosts and transfer by fusion into cultured murine recipient cells [PDF]
, 1976 Wolfgang Wille, Klaus Willecke
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Induced degradation of SNAP-fusion proteins
RSC Chemical BiologyExtending the applications of the SNAP-tag: VHL- and CRBN-recruiting SNAP-PROTACs provide a ready-to-use targeted protein degradation system for SNAP-fusion proteins.
Savina Abraham Pol +11 more
openaire +4 more sources
Surfaceome: a new era in the discovery of immune evasion mechanisms of circulating tumor cells
Molecular Oncology, EarlyView.In the era of immunotherapies, many patients either do not respond or eventually develop resistance. We propose to pave the way for proteomic analysis of surface‐expressed proteins called surfaceome, of circulating tumor cells. This approach seeks to identify immune evasion mechanisms and discover potential therapeutic targets. Circulating tumor cells (
Doryan Masmoudi +3 more
wiley +1 more source
On the origin and diversity of Newcastle disease virus in Tanzania
Onderstepoort Journal of Veterinary Research, 2011 Free-range rural chickens (FRCs) dominate the poultry industry in developing countries and chickens are exposed to multi-host infections, including Newcastle disease virus (NDV). The knowledge about the characteristics of NDV from FRCs is limited. This
Mmeta G. Yongolo +4 more
doaj +1 more source
Integration of a virus membrane protein intothe lipid bilayer of target cells as a prerequisite for immune cytolysis. Specific cytolysis after virosome- target cell fusion [PDF]
, 1978 Brør Morein +3 more
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Spider silk-bone sialoprotein fusion proteins for bone tissue engineering [PDF]
, 2011 The remarkable mechanical characteristics of the spider silk protein major ampullate spidroin protein suggest this polymer as a promising biomaterial to consider for the fabrication of scaffolds for bone regeneration.
Gomes, Sílvia C. +4 more
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