Results 11 to 20 of about 1,121,449 (385)
Versatile toolbox for high throughput biochemical and functional studies with fluorescent fusion proteins [PDF]
, 2012 Fluorescent fusion proteins are widely used to study protein localization and interaction dynamics in living cells. However, to fully characterize proteins and to understand their function it is crucial to determine biochemical characteristics such as ...
Hake, Sandra B. +3 more
core +20 more sources
High Accuracy Protein Identification: Fusion of solid-state nanopore sensing and machine learning [PDF]
Small Methods 2023, 2300676, 2023 Proteins are arguably the most important class of biomarkers for health diagnostic purposes. Label-free solid-state nanopore sensing is a versatile technique for sensing and analysing biomolecules such as proteins at single-molecule level. While molecular-level information on size, shape, and charge of proteins can be assessed by nanopores, the ...
arxiv +1 more source
Frontiers in Microbiology, 2022 Rift Valley fever virus (RVFV), a mosquito-borne zoonotic phlebovirus, causes serious disease in humans and ruminants. According to the World Health Organization, Rift Valley fever is classified as a priority disease, and as such, vaccine development is ...
Shengnan Zhang +10 more
doaj +1 more source
A Pan-Pneumovirus vaccine based on immunodominant epitopes of the fusion protein
Frontiers in Immunology, 2022 Respiratory syncytial virus (RSV) and human metapneumovirus (hMPV) are two leading causes of severe respiratory infections in children, the elderly, and immunocompromised patients.
Jiachen Huang +6 more
doaj +1 more source
Protective antibodies against human parainfluenza virus type 3 infection
mAbs, 2021 Human parainfluenza virus type III (HPIV3) is a common respiratory pathogen that afflicts children and can be fatal in vulnerable populations, including the immunocompromised. There are currently no effective vaccines or therapeutics available, resulting
Jim Boonyaratanakornkit +10 more
doaj +1 more source
Cyanobacterial Production of Biopharmaceutical and Biotherapeutic Proteins
Frontiers in Plant Science, 2020 Efforts to express human therapeutic proteins in photosynthetic organisms have been described in the literature. Regarding microalgae, most of the research entailed a heterologous transformation of the chloroplast, but transformant cells failed to ...
Nico Betterle +2 more
doaj +1 more source
Avian Paramyxovirus Type 1 in Egypt: Epidemiology, Evolutionary Perspective, and Vaccine Approach
Frontiers in Veterinary Science, 2021 Avian orthoavulavirus 1, formerly known as avian paramyxovirus type-1 (APMV-1), infects more than 250 different species of birds. It causes a broad range of clinical diseases and results in devastating economic impact due to high morbidity and mortality ...
Shimaa M. G. Mansour +8 more
doaj +1 more source
Frontiers in Cell and Developmental Biology, 2021 We describe, for the first time, a new splice variant of the human TGF-β type II receptor (TβRII). The new transcript lacks 149 nucleotides, resulting in a frameshift and the emergence of an early stop codon, rendering a truncated mature protein of 57 ...
Marcela Soledad Bertolio +11 more
doaj +1 more source
Frontiers in Molecular Neuroscience, 2009 Synchronous neural activity occurs throughout the brain in association with normal and pathological brain functions. Despite theoretical work exploring how such neural coordination might facilitate neural computation and be corrupted in disease states ...
Xue Han +10 more
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Expression in Escherichia coli of a cloned DNA sequence encoding the pre-S2 region of hepatitis B virus [PDF]
, 1985 A DNA sequence encoding the entire pre-S2 region (amino acids 120-174; serotype ayw) of human hepatitis B virus envelope protein has been inserted into the lacZ gene of the plasmid pSKS105 yielding a recombinant, pWS3.
Acs, George +7 more
core +1 more source