Results 11 to 20 of about 724,119 (263)
Fusion proteins and fusion pores [PDF]
EMBO reports, 2000 Sponsored by the Juan March Foundation and organized by R D Burgoyne and G Alvarez de Toledo, Madrid, Spain, May 22–24, 2000. ![][1] A meeting was recently held at the Juan March Foundation in Madrid (22–24 May, 2000) on the topic ‘Regulated exocytosis and the vesicle cycle’.
R D, Burgoyne, G, Alvarez de Toledo
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Structure of the Core Postfusion Porcine Endogenous Retrovirus Fusion Protein
mBio, 2022 Retroviral elements from endogenous retroviruses have functions in mammalian physiology. The best-known examples are the envelope proteins that function in placenta development and immune suppression.
Trevor T. Dean +2 more
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Immune Checkpoints, a Novel Class of Therapeutic Targets for Autoimmune Diseases
Frontiers in Immunology, 2021 Autoimmune diseases, such as multiple sclerosis and type-1 diabetes, are the outcomes of a failure of immune tolerance. Immune tolerance is sustained through interplays between two inter-dependent clusters of immune activities: immune stimulation and ...
Yujia Zhai, Reza Moosavi, Mingnan Chen
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Cyanobacterial Production of Biopharmaceutical and Biotherapeutic Proteins
Frontiers in Plant Science, 2020 Efforts to express human therapeutic proteins in photosynthetic organisms have been described in the literature. Regarding microalgae, most of the research entailed a heterologous transformation of the chloroplast, but transformant cells failed to ...
Nico Betterle +2 more
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Frontiers in Immunology, 2021 Soft tissue sarcoma (STS) constitutes a rare group of heterogeneous malignancies. Effective treatment options for most subtypes of STS are still limited. As a result, especially in metastatic disease, prognosis is still dismal.
Ilona Hagelstein +23 more
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A Novel GLP-1 and FGF21 Fusion Protein for the Treatment of Non-alcoholic Steatohepatitis (NASH) [PDF]
Advanced Pharmaceutical BulletinPurpose: The objective of this study was to develop and produce a novel fusion protein that combines GLP-1 (glucagon-like peptide-1) and FGF21 (fibroblast growth factor 21), with the aim of achieving synergistic pharmacological effects through the ...
Zhipeng Zhang +7 more
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Fermentation, 2023 Phycocyanobilin (PCB) is the bioactive chromophore attached to Phycocyanin (PC) that is of special interest for nutraceutical and therapeutic applications. However, the production of PCB from the heterologous host Escherichia coli is still very low.
Xiaolin Liu +5 more
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Antioxidants, 2021 Methionine sulfoxide reductase (Msr) is a family of enzymes that reduces oxidized methionine and plays an important role in the survival of bacteria under oxidative stress conditions.
Sulhee Kim +6 more
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Evaluation of the Effects of Human Beta-Interferon Scaffold Attachment Region (IFN-SAR) on Expression of Vascular Endothelial Growth Factor-Fc (VEGF-Fc) Fusion Protein Expression in Chinese Hamster Ovary (CHO) Cells [PDF]
Pharmaceutical Sciences, 2020 Background: Recombinant anti-vascular endothelial growth factor (VEGF) monoclonal antibodies and Fc-fusion proteins have been widely used for the effective treatment of retinal neovascular diseases.
Ehsan Naghneh +2 more
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A Pan-Pneumovirus vaccine based on immunodominant epitopes of the fusion protein
Frontiers in Immunology, 2022 Respiratory syncytial virus (RSV) and human metapneumovirus (hMPV) are two leading causes of severe respiratory infections in children, the elderly, and immunocompromised patients.
Jiachen Huang +6 more
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