Results 331 to 340 of about 7,331,516 (404)

Probing Early Particle‐Cell Membrane Interactions via Single‐Cell and Single‐Particle Interaction Analysis

Advanced Functional Materials, EarlyView.
The pre‐internalization phase of endocytosis remains poorly characterized at single‐cell levels. Single‐cell pre‐internalization mechanics are investigated using advanced robotic techniques. Cancer cells exhibit biphasic adhesion – rapid initial binding followed by reinforcement – while fibroblasts show gradual engagement.
Houari Bettahar, Christos Tapeinos, Oğulcan Işıtman, Carmine D'Amico, Alexandra Correia, Hélder A. Santos, Quan Zhou   +6 more
wiley   +1 more source

Second generation CD2-targeting LFA-3 fusion protein SBT115301 to restore immune homeostasis in autoimmune disease. [PDF]

iScience
Lebrec H, Bui J, Clingan JM, Do J, Dubovsky J, Dragone L, Gibiansky E, Lam WY, Matsuda K, Mihalcik L, Ramsdell F, van der Vuurst de Vries AR, Xiao Y, Bluestone JA.   +13 more
europepmc   +1 more source

The APL-associated fusion proteins.

Haematologica, 1999
S. Minucci, M. Cioce, M. Maccarana, P. G. Pelicci   +3 more
openaire   +2 more sources

Cell‐Delivering Injectable Hydrogels with Tunable Microporous Structures Improve Therapeutic Efficacy for Volumetric Muscle Loss

Advanced Functional Materials, EarlyView.
The study presents an injectable hydrogel with tunable microporosity to improve mesenchymal stem cell delivery for volumetric muscle loss treatment. Mesenchymal stem cells encapsulated in porous hydrogels significantly promote the spreading, proliferation, and cytokine secretion of mesenchymal stem cells.
Hana Yasue, Tetsushi Taguchi, Taka‐Aki Asoh, Akihiro Nishiguchi   +3 more
wiley   +1 more source

Development and Potent Anti-Tumor Activity of a Fully Humanized Anti-TAG-72-IL-2 Fusion Protein for Therapy of Solid Tumors. [PDF]

Cancers (Basel)
Aniogo E, Williams L, Hong T, Wong P, Hui SK, Ghimire H, Poku EK, Colcher DM, Yazaki PJ, Shively JE, Kujawski M.   +10 more
europepmc   +1 more source

Engineering Topographical Cues to Enhance Neural Regeneration in Spinal Cord Injury: Overcoming Challenges and Advancing Therapies

Advanced Functional Materials, EarlyView.
Spinal cord injury (SCI) poses significant challenges for regeneration due to a series of secondary injury mechanisms. How to use biomaterial approach to target the failed regeneration after SCI remains a critical challenge. This review systematically evaluates current strategies to optimize biomaterial topographies for neurite outgrowth, axonal ...
Wei Xu, Fenghui Wang, Joshua Stein, Siqiao Wang, Pengfei Jiang, Letao Yang, Liming Cheng, Ki‐Bum Lee   +7 more
wiley   +1 more source

ROS-responsive death receptor 5 fusion protein nano-delivery system enhances myocardial ischemia-reperfusion injury protection. [PDF]

Mater Today Bio
Liang X, Zhang Y, Wang C, Li H, Li Q, Ye Y, Tu C, Zhao X, Yang J, Zeng Y.   +9 more
europepmc   +1 more source

Kirigami‐Inspired Breathable Smart Contact Lens for Wireless Monitoring of Corneal Hypoxia and Microenvironment

Advanced Healthcare Materials, EarlyView.
A kirigami‐inspired breathable smart contact lens is reported for wireless monitoring of corneal hypoxia and microenvironment. The ultrathin (55 µm) and flexible sensing device enables digitalized, in situ and precise monitoring of dissolved oxygen, humidity, and temperature (R2 >0.98).
Jiaxue Zhu, Ling Yang, Qing Yang, Yin Huang, Yuhang Li, Yueqing He, Xuxu Yang, Zhiyan Yang, Yonghong Jiao, Wenbin Wei, Yihao Chen, Xue Feng   +11 more
wiley   +1 more source

3D Bioprinted Head and Neck Squamous Cell Carcinoma (HNSCC) Model Using Tunicate Derived Nanocellulose (NC) Bioink

Advanced Healthcare Materials, Volume 14, Issue 7, March 14, 2025.
A 3D bioprinted HNSCC model for use in anti‐cancer drug testing is established in proof‐of‐concept. The innovative tunicate‐derived nanocellulose hydrogel proved to be a viable alternative to gelatin‐based hydrogel, offering improved bioprintability for HNSCC model establishment.
Alexya Azhakesan, Johann Kern, Ankit Mishra, Christine Selhuber‐Unkel, Annette Affolter, Paul Gatenholm, Nicole Rotter, Karen Bieback   +7 more
wiley   +1 more source

3D-Printed Biomimetic Vascular Scaffold Crosslinked with Heparan Sulfate for Sustained Release of PDGFB-LG4 Fusion Protein Promotes Bone Regeneration. [PDF]

Adv Sci (Weinh)
Duan J, Qian G, Zhang H, Wang F, Tian Q, Lei D, Zhao J.   +6 more
europepmc   +1 more source