FusionPDB: a knowledgebase of human Fusion Proteins
Nucleic Acids Research, 2023 Abstract Tumorigenic functions due to the formation of fusion genes were targeted for cancer therapeutics (i.e., kinase inhibitors). However, many fusion proteins are still awaiting being targeted for therapeutics in diverse cellular working mechanisms.
Himansu Kumar +3 more
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Crystallization of the oligopeptide-binding protein AppA from Bacillus subtilis [PDF]
, 2004 AppA is the membrane-anchored extracellular receptor component of an ABC transporter responsible for the uptake of oligopeptides into Bacillus subtilis.
Blagova, E +6 more
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mCherry contains a fluorescent protein isoform that interferes with its reporter function
Frontiers in Bioengineering and Biotechnology, 2022 Fluorescent proteins are essential reporters in cell and molecular biology. Here, we found that red-fluorescent proteins possess an alternative translation initiation site that produces a short functional protein isoform in both prokaryotes and ...
Maxime Fages-Lartaud +5 more
doaj +1 more source
Construction and assessment of the immunogenicity and bactericidal activity of fusion protein porin A from Neisseria meningitidis serogroups A and B admixed with OMV adjuvant as a novel vaccine candidate [PDF]
Iranian Journal of Basic Medical Sciences, 2020 Objective(s): The porins A and B and also outer membrane vesicles (OMVs) of Neisseria meningitidis are used for vaccine purposes. In the present study, we aimed to design a new vaccine candidate based on a fusion of PorA of serogroups A and B of N ...
Parviz Afrough +4 more
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Monomeric ephrinB2 binding induces allosteric changes in Nipah virus G that precede its full activation. [PDF]
, 2017 Nipah virus is an emergent paramyxovirus that causes deadly encephalitis and respiratory infections in humans. Two glycoproteins coordinate the infection of host cells, an attachment protein (G), which binds to cell surface receptors, and a fusion (F ...
Jardetzky, Theodore S +9 more
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Research on mechanical properties of Bacillus subtilis biofilm expressing TasA-n16N
He jishu, 2022 BackgroundBacterial biofilm is a structure formed by bacteria communities living in a self-produced matrix of extracellular polymeric substances (EPS) composed of polysaccharides, proteins, nucleic acids, and so on.
QIN Simin, LIU Suying, ZHU Ying, LYU Min
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Class II Fusion Proteins [PDF]
, 2013 Enveloped viruses rely on fusion proteins in their envelope to fuse the viral membrane to the host-cell membrane. This key step in viral entry delivers the viral genome into the cytoplasm for replication. Although class II fusion proteins are genetically and structurally unrelated to class I fusion proteins, they use the same physical principles and ...
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Reprogramming Hansenula polymorpha for penicillin production: expression of the Penicillium chrysogenum pcl gene [PDF]
, 2007 We aim to introduce the penicillin biosynthetic pathway into the methylotrophic yeast Hansenula polymorpha. To allow simultaneous expression of the multiple genes of the penicillin biosynthetic pathway, additional markers were required.
Gidijala, Loknath, +3 more
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The Computation of Cyclic Peptide with Prolin-Prolin Bond as Fusion Inhibitor of DENV Envelope Protein through Molecular Docking and Molecular Dynamics Simulation [PDF]
, 2015 A disease that caused by dengue virus (DENV) has become the major health problem of the world. Nowadays, no effective treatment is available to overcome the disease due to the level of dengue virus pathogeneses. A novel treatment method such as antiviral drug is highly necessary for coping with the dengue disease.
arxiv +1 more source
Fusion Protein TM-TM Interactions: Modulators of Pre-Fusion Protein Stability [PDF]
Biophysical Journal, 2016 Membrane associated domains of proteins are often under-studied because of their lipid environment, however recent studies suggest that protein transmembrane domains (TMDs) are important for cell signaling events, and protein oligomerization. Enveloped viruses utilize fusion proteins (F) studding the envelope of the virus to promote fusion of the viral
Rebecca Ellis Dutch, Stacy R. Webb
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