Results 181 to 186 of about 21,002 (186)

Detection and significance of bcr-abl mRNA transcripts and fusion proteins in Philadelphia-positive adult acute lymphoblastic leukemia.

Leukemia, 1993
Blast cells from an unselected consecutive series of 84 adults presenting with acute lymphoblastic leukemia (ALL) to St Bartholomew's Hospital over a seven year period were tested prospectively by cytogenetic and retrospectively by RT-PCR analysis for the presence of the Ph translocation and bcr-abl mRNA. This combination gave an overall figure of 20.3%
A, Tuszynski, S, Dhut, B D, Young, T A, Lister, A Z, Rohatiner, J A, Amess, T, Chaplin, E, Dorey, B, Gibbons   +8 more
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Establishment and molecular characterization of a novel leukemic cell line with Philadelphia chromosome expressing p230 BCR/ABL fusion protein.

Cancer research, 1995
The cell line AR230 was established from the peripheral blood mononuclear cells of a patient with chronic myeloid leukemia and t(9;22) translocation bearing a variant type of BCR/ABL rearrangement. AR230 expresses a BCR/ABL fusion protein with a molecular mass of 230 kilodaltons (kDa) due to the insertion of 180 amino acids encoded by 3' exons of BCR ...
H, Wada, S, Mizutani, J, Nishimura, Y, Usuki, M, Kohsaki, M, Komai, H, Kaneko, S, Sakamoto, D, Delia, A, Kanamaru   +9 more
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Two bcr/abl fusion gene products, P210bcr/abl and P190bcr/abl, are equally sensitive to the protein tyrosine phosphatase of mature granulocytes.

International journal of hematology, 1992
Two bcr/abl fusion gene products with tyrosine kinase activity have been found in two phenotypes of Philadelphia chromosome (Ph1)-positive leukemia. P210bcr/abl (P210) is associated with Ph1-positive chronic myelogenous leukemia (CML), while P190bcr/abl is associated with Ph1-positive acute leukemia.
J, Nishimura, J, Okamura, K, Shibata, H, Takahira, Y, Yufu, S, Kato, J, Hirata, T, Umemura, H, Nawata   +8 more
openaire   +1 more source

[Signal transduction BCR-ABL fusion protein: analysis of BCR-ABL functional domains].

[Rinsho ketsueki] The Japanese journal of clinical hematology, 1998
T, Tauchi, S, Okabe, K, Oyashiki, K, Sotoyama   +3 more
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BCR‐ABL Fusion Protein

2008
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Effect of diphtheria toxin on myeloid cells bearing the fusion protein BCR/ABL.

2000
VINANTE, Fabrizio, RIGO, Antonella, PIZZOLO, Giovanni   +2 more
openaire   +1 more source