Lectin-Fc(IgG) fusion proteins exhibit antifungal activity against the emerging multidrug-resistant pathogen Candida auris [PDF]
Infection and ImmunityCandida auris is an emerging fungal pathogen recognized among the Centers for Disease Control and Prevention’s urgent threats and designated a critical priority by the World Health Organization due to its global spread, high mortality rates, potential ...
Susana Ruiz Mendoza +7 more
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Novel Hydrophobin Fusion Tags for Plant-Produced Fusion Proteins [PDF]
PLOS ONE, 2016 Hydrophobin fusion technology has been applied in the expression of several recombinant proteins in plants. Until now, the technology has relied exclusively on the Trichoderma reesei hydrophobin HFBI. We screened eight novel hydrophobin tags, T. reesei HFBII, HFBIII, HFBIV, HFBV, HFBVI and Fusarium verticillioides derived HYD3, HYD4 and HYD5, for ...
Reuter, Lauri +4 more
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Viral fusion proteins of classes II and III recognize and reorganize complex biological membranes [PDF]
Communications BiologyViral infection requires stable binding of viral fusion proteins to host membranes, which contain hundreds of lipid species. The mechanisms by which fusion proteins utilize specific host lipids to drive virus–host membrane fusion remains elusive.
Chetan S. Poojari +2 more
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Development and evaluation of multiepitope fusion proteins for serological diagnosis of animal brucellosis [PDF]
Microbiology SpectrumBrucellosis, a zoonotic disease caused by Brucella spp., leads to severe reproductive issues in livestock and economic losses. Current serological diagnostics using lipopolysaccharide (LPS) antigens often exhibit cross-reactivity, reducing diagnostic ...
Liping Guo +9 more
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Comparison of antibody-scTRAIL Fc fusion proteins with varying valency for EGFR and TRAIL receptors [PDF]
Scientific ReportsFusion proteins combining TNF-related apoptosis inducing ligand (TRAIL) and antibody building blocks have emerged as a strategy for the targeted treatment of cancer cells.
Dennis Michler +3 more
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Editorial: Fusion proteins for the detection of pathogens or pathogen receptors [PDF]
Frontiers in Bioengineering and BiotechnologyRoger M. Benoit
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Biophysica, 2022 Bioluminescence resonance energy transfer (BRET) seems to be a promising biophysical technique to study protein–protein interactions within living cells due to a very specific reaction of bioluminescence that essentially decreases the background of other
Victor Marchenkov +4 more
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Double Proteolysis for N- and O-glycan Analysis of Fc-fusion Protein Etanercept
Разработка и регистрация лекарственных средств, 2023 Introduction. Highly glycosylated proteins are the most abundant class of modern biopharmaceuticals. A majority of such therapeuticals produced by Russian biopharmaceutical companies is biosimilars.
V. G. Varzieva +4 more
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ViralFP: A Web Application of Viral Fusion Proteins
Frontiers in Medical Technology, 2021 Viral fusion proteins are attached to the membrane of enveloped viruses (a group that includes Coronaviruses, Dengue, HIV and Influenza) and catalyze fusion between the viral and host membranes, enabling the virus to insert its genetic material into the ...
Pedro Moreira +5 more
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Fusion proteins and fusion pores [PDF]
EMBO reports, 2000 Sponsored by the Juan March Foundation and organized by R D Burgoyne and G Alvarez de Toledo, Madrid, Spain, May 22–24, 2000. ![][1] A meeting was recently held at the Juan March Foundation in Madrid (22–24 May, 2000) on the topic ‘Regulated exocytosis and the vesicle cycle’.
R D, Burgoyne, G, Alvarez de Toledo
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