Results 21 to 30 of about 978,977 (295)

RECOMBINANT HORSERADISH PEROXIDASE FOR ANALYTICAL APPLICATIONS [PDF]

open access: yesBiotechnologia Acta, 2012
The article deals with prospects of using recombinant horseradish peroxidase in analytical biochemistry and biotechnology. Problems of recombinant horseradish peroxidase cloning in different expression systems, possible approaches to their solution ...
А.M. Egorov   +3 more
doaj   +1 more source

Identification and Characteristics of Fusion Peptides Derived From Enveloped Viruses

open access: yesFrontiers in Chemistry, 2021
Membrane fusion events allow enveloped viruses to enter and infect cells. The study of these processes has led to the identification of a number of proteins that mediate this process. These proteins are classified according to their structure, which vary
Camille Lozada   +5 more
doaj   +1 more source

Synaptic proteins promote calcium-triggered fast transition from point contact to full fusion. [PDF]

open access: yes, 2012
The molecular underpinnings of synaptic vesicle fusion for fast neurotransmitter release are still unclear. Here, we used a single vesicle-vesicle system with reconstituted SNARE and synaptotagmin-1 proteoliposomes to decipher the temporal sequence of ...
Brunger, Axel T   +13 more
core   +1 more source

C-terminal eYFP fusion impairs Escherichia coli MinE function [PDF]

open access: yesOpen Biology, 2020
The Escherichia coli Min system plays an important role in the proper placement of the septum ring at mid-cell during cell division. MinE forms a pole-to-pole spatial oscillator with the membrane-bound ATPase MinD, resulting in MinD concentration being ...
Navaneethan Palanisamy   +3 more
doaj   +1 more source

Structure and function of bacterial dynamin-like proteins [PDF]

open access: yes, 2012
Membrane dynamics are essential for numerous cellular processes in eukaryotic and prokaryotic cells. In eukaryotic cells, membrane fusion and fission are often catalyzed by large GTPases of the dynamin protein family. These proteins couple GTP hydrolysis
Bramkamp, Marc
core   +1 more source

CemOrange2 fusions facilitate multifluorophore subcellular imaging in C. elegans [PDF]

open access: yes, 2019
Due to its ease of genetic manipulation and transparency, Caenorhabditis elegans (C. elegans) has become a preferred model system to study gene function by microscopy.
Buland, Justin R   +14 more
core   +3 more sources

Chimeric piggyBac transposases for genomic targeting in human cells. [PDF]

open access: yes, 2012
Integrating vectors such as viruses and transposons insert transgenes semi-randomly and can potentially disrupt or deregulate genes. For these techniques to be of therapeutic value, a method for controlling the precise location of insertion is required ...
Belcaid, Mahdi   +9 more
core   +5 more sources

A virus-encoded cell-cell fusion machine dependent on surrogate adhesins. [PDF]

open access: yesPLoS Pathogens, 2008
The reovirus fusion-associated small transmembrane (FAST) proteins function as virus-encoded cellular fusogens, mediating efficient cell-cell rather than virus-cell membrane fusion. With ectodomains of only approximately 20-40 residues, it is unclear how
Jayme Salsman   +3 more
doaj   +1 more source

Use of single-chain antibody derivatives for targeted drug delivery [PDF]

open access: yes, 2016
Single-chain antibodies (scFvs), which contain only the variable domains of full-length antibodies, are relatively small molecules that can be used for selective drug delivery.
Ahmadzadeh, V.   +5 more
core   +1 more source

Molecular Engineering of Therapeutic Cytokines

open access: yesAntibodies, 2013
Over the past three decades, a large body of work has been directed at the development of therapeutic cytokines. Despite their central role in immune modulation, only a handful of cytokine therapeutics has achieved regulatory approval.
Daniel Christ   +2 more
doaj   +1 more source

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