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Viral membrane fusion [PDF]

Virology, 2015
Infection by viruses having lipid-bilayer envelopes proceeds through fusion of the viral membrane with a membrane of the target cell. Viral 'fusion proteins' facilitate this process. They vary greatly in structure, but all seem to have a common mechanism of action, in which a ligand-triggered, large-scale conformational change in the fusion protein is ...
Stephen C. Harrison
openalex   +4 more sources

SNAREs — engines for membrane fusion [PDF]

Nature Reviews Molecular Cell Biology, 2006
Since the discovery of SNARE proteins in the late 1980s, SNAREs have been recognized as key components of protein complexes that drive membrane fusion. Despite considerable sequence divergence among SNARE proteins, their mechanism seems to be conserved and is adaptable for fusion reactions as diverse as those involved in cell growth, membrane repair ...
Reinhard Jahn, Richard H Scheller, Jahn Reinhard   +2 more
exaly   +4 more sources

Membrane fusion [PDF]

Nature Structural & Molecular Biology, 2008
Subcellular compartmentalization, cell growth, hormone secretion and neurotransmission require rapid, targeted, and regulated membrane fusion. Fusion entails extensive lipid rearrangements by two apposed (docked) membrane vesicles, joining their membrane proteins and lipids and mixing their luminal contents without lysis.
William, Wickner, Randy, Schekman
  +7 more sources

Membrane fusion and budding. [PDF]

Biophys J
Anantharam A, Knowles MK, Wu LG.
europepmc   +3 more sources

The ARF regulatory GTPase in Giardia intestinalis is associated with vesicle formation and membrane fusion machinery at non-canonical endosomal compartments [PDF]

Pipaliya SV, Kingdon EM, Wirdnam CD, Balmer EA, Kahn RA, Dacks JB, Faso C.   +6 more
europepmc   +2 more sources

Membrane Fusion [PDF]

Cell, 2003
Membrane fusion, one of the most fundamental processes in life, occurs when two separate lipid membranes merge into a single continuous bilayer. Fusion reactions share common features, but are catalyzed by diverse proteins. These proteins mediate the initial recognition of the membranes that are destined for fusion and pull the membranes close together
Jahn, R., Lang, T., Suedhof, T.
openaire   +3 more sources

A broadly neutralizing antibody confers cross-genus protection against alphaherpesviruses by inhibiting gB-mediated membrane fusion. [PDF]

Nat Commun
Wang G, Li Y, Wu C, Chen T, Gui M, Zeng Y, Sun H, Chen K, Xi X, Yang Y, Jiang Y, Jiang Y, Liu L, Yang C, Xin J, Liu C, Li Y, Huo N, Huang Y, Lin L, Yu H, Huang C, Yuan Q, Li S, Tian K, Zheng Q, Xia N, Chen Y.   +27 more
europepmc   +3 more sources

Membrane Fusion

Chemical Reviews, 2002
AbstractFor Abstract see ChemInform Abstract in Full Text.
Robert, Blumenthal, Michael J, Clague, Stewart R, Durell, Richard M, Epand   +3 more
openaire   +6 more sources

Membrane tension and membrane fusion [PDF]

Current Opinion in Structural Biology, 2015
Diverse cell biological processes that involve shaping and remodeling of cell membranes are regulated by membrane lateral tension. Here we focus on the role of tension in driving membrane fusion. We discuss the physics of membrane tension, forces that can generate the tension in plasma membrane of a cell, and the hypothesis that tension powers ...
Michael M, Kozlov, Leonid V, Chernomordik   +1 more
openaire   +2 more sources

Fusion of secretory vesicles isolated from rat liver [PDF]

, 1978
Secretory vesicles isolated from rat liver were found to fuse after exposure to Ca2+. Vescle fusion is characterized by the occurrence of twinned vesicles with a continuous cleavage plane between two vesicles in freeze-fracture electron microscopy.
Dahl, Gerhard, Dahl, G., Gratzl, Manfred   +2 more
core   +1 more source