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In vitro assays to monitor membrane fusion [PDF]
Frontiers in Cell and Developmental BiologyMembrane fusion is essential to maintain eukaryotic life. Fusion is tightly regulated and relies on a complex network of protein tethers and lipid interactions.
Hunter J. Madison, Adam L. Yokom
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From Population Averaging to Single Event Resolution: Evolution of Sensing Platforms for Membrane Fusion [PDF]
SensorsMembrane fusion is fundamental to intracellular transport and signal transduction, with its dysregulation implicated in various diseases. Deciphering its transient, microscale dynamics requires advanced sensing technologies.
Yazhuo Feng +4 more
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Alphavirus Entry and Membrane Fusion
Viruses, 2010 The study of enveloped animal viruses has greatly advanced our understanding of the general properties of membrane fusion and of the specific pathways that viruses use to infect the host cell.
Margaret Kielian +2 more
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Unravelling the role of key amino acid residues of the parainfluenza fusion peptide in membrane fusion [PDF]
RSC Chemical BiologyParainfluenza viruses enter host cells by fusing their envelope with the cell membrane. In this process mediated by the fusion glycoprotein, the fusion peptide plays an essential role in membrane binding and triggering fusion. Previously, we demonstrated
Mariana Valério +7 more
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Simulation and prediction of membrane fusion dynamics
Theoretical and Applied Mechanics Letters, 2022 Membrane fusion is an important process by which biological membranes perform their life activities. Simulations show that the membrane fusion process happens mainly through three pathways, where the Stalk-Pore hypothesis, in which two membranes come ...
Zhi Zheng, Shouqin Lü, Mian Long
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The Effects of Regulatory Lipids on Intracellular Membrane Fusion Mediated by Dynamin-Like GTPases
Frontiers in Cell and Developmental Biology, 2020 Membrane fusion mediates a number of fundamental biological processes such as intracellular membrane trafficking, fertilization, and viral infection. Biological membranes are composed of lipids and proteins; while lipids generally play a structural role,
Yeojin Moon, Youngsoo Jun
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A Frame-by-Frame Glance at Membrane Fusion Mechanisms: From Viral Infections to Fertilization
Biomolecules, 2023 Viral entry and fertilization are distinct biological processes that share a common mechanism: membrane fusion. In viral entry, enveloped viruses attach to the host cell membrane, triggering a series of conformational changes in the viral fusion proteins.
Farshad C. Azimi +5 more
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Viruses, 2020 Protein-mediated membrane fusion is a highly regulated biological process essential for cellular and organismal functions and infection by enveloped viruses. During viral entry the membrane fusion reaction is catalyzed by specialized protein machinery on
Mark A. Benhaim, Kelly K. Lee
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Phospholipases and Membrane Curvature: What Is Happening at the Surface?
Membranes, 2023 In this revision work, we emphasize the close relationship between the action of phospholipases and the modulation of membrane curvature and curvature stress resulting from this activity.
María Laura Fanani +1 more
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Two coiled-coil domains of Chlamydia trachomatis IncA affect membrane fusion events during infection. [PDF]
PLoS ONE, 2013 Chlamydia trachomatis replicates in a parasitophorous membrane-bound compartment called an inclusion. The inclusions corrupt host vesicle trafficking networks to avoid the degradative endolysosomal pathway but promote fusion with each other in order to ...
Erik Ronzone, Fabienne Paumet
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