Results 21 to 30 of about 556,464 (304)

Membrane Fusion: Caught in a Trap [PDF]

Current Biology, 2004
SNAREs are small coiled-coil proteins required for specific membrane fusion events in eukaryotic cells. Recent evidence points to the existence of an inhibitory class of SNAREs, i-SNAREs, which prevent incorrect fusions from occurring, adding a further layer of regulation to the process of membrane docking and fusion.
Short, B., Barr, F.
openaire   +3 more sources

The nanoscale organization of the Nipah virus fusion protein informs new membrane fusion mechanisms. [PDF]

Elife
Wang Q, Liu J, Luo Y, Kliemke V, Matta GL, Wang J, Liu Q.   +6 more
europepmc   +2 more sources

The structure of Herpesvirus Fusion Glycoprotein B-Bilayer Complex reveals the protein-membrane and lateral protein-protein interaction

, 2013
Glycoprotein B (gB) is a key component of the complex herpesvirus fusion machinery. We studied membrane interaction of two gB ectodomain forms and present an electron cryotomography structure of the gB-bilayer complex.
Topf, Maya, Huiskonen, JT, Topf, M., Maurer, U., Whitbeck, J., Maurer, U.E., Gruenewald, Kay, Cohen, G., Cairns, T.M., Eisenberg, R.J., Huiskonen, Juha T., Whitbeck, J.C., Zeev-Ben-Mordehai, T, Cohen, Gary H., Cohen, GH, Cairns, Tina M., Hannah, BP, Hannah, B.P., Cohen, G.H., Pandurangan, A., Zeev-Ben-Mordehai, T., Grünewald, K, Eisenberg, Roselyn J., Cairns, T., Huiskonen, J.T., Maurer, Ulrike E., Grünewald, Kay, Eisenberg, RJ, Topf, M, Grünewald, K., Maurer, UE, Pandurangan, Arun Prasad, Whitbeck, JC, Zeev-Ben-Mordehai, Tzviya, Huiskonen, J., Hannah, Brian P., Hannah, B., Pandurangan, Arun, Pandurangan, AP, Eisenberg, R., Whitbeck, J. Charles, Cairns, TM   +41 more
core   +1 more source

On the study of catalytic membrane reactor for water detritiation: Membrane characterization. [PDF]

, 2013
Tritium waste recycling is a real economic and ecological issue. Generally under the non-valuable Q2Oform (Q = H, D or T), waste can be converted into fuel Q2for a fusion machine (e.g. JET, ITER) by isotopeexchange reaction Q2O + H2= H2O + Q2.
Liger, Karine, Mascarade, Jérémy, Troulay, Michèle, Tosti, Silvano, Joulia, Xavier, Meyer, Xuân-Mi, Perrais, Christophe   +6 more
core   +1 more source

INSIGHTS ON MEMBRANE FUSION [PDF]

Cell Biology International, 2000
AbstractMembrane fusion is a fundamental cellular process regulating intracellular transport, neurotransmission, enzyme secretion, hormone release, and the entry/exit of viruses, to name a few. Knowledge of how opposing bilayers fuse, besides advancing our understanding of these cellular processes, will provide us with the facts to ameliorate secretory
openaire   +2 more sources

Sequential SNARE disassembly and GATE-16-GOS-28 complex assembly mediated by distinct NSF activities drives Golgi membrane fusion

, 2002
Characterization of mammalian NSF (G274E) and Drosophila NSF (comatose) mutants revealed an evolutionarily conserved NSF activity distinct from ATPase-dependent SNARE disassembly that was essential for Golgi membrane fusion.
Yuval Sagiv, Zvulun Elazar, Katrin Deinhardt, Richard Newman, Graham Warren, Shima, David T., Müller, Joyce M.M., Warren, Graham, David T. Shima, James Shorter, Sagiv, Yuval, Joyce M.M. Müller, Shorter, James, Newman, Richard, Elazar, Zvulun, Deinhardt, Katrin   +15 more
core   +1 more source

Munc 18-1 Protein Molecules Move between Membrane Molecular Depots Distinct from Vesicle Docking Sites [PDF]

, 2013
Four evolutionarily conserved proteins are required for mammalian regulated exocytosis: three SNARE proteins, syntaxin, SNAP-25, and synaptobrevin, and the SM protein, Munc18-1. Here, using single-molecule imaging, we measured the spatial distribution of
Rickman, Colin, Lu, Weiping, Yang, Lei, Hamilton, Charlotte, Smyth, Annya M., Cousin, Michael A., Rickman, Colin; id_orcid, Martin, Kirsty J., Duncan, Rory R., Cousin, Michael A.; id_orcid   +9 more
core   +1 more source

Illuminating membrane fusion [PDF]

Proceedings of the National Academy of Sciences, 2006
Membrane fusion is a central event for a wide variety of biological processes, such as transport of cargo through the secretory and endocytic pathways, organelle inheritance, neurotransmission, and viral entry into host cells, among others. Hence, understanding the mechanism(s) of physiological membrane fusion is a subject of wide biological interest ...
openaire   +2 more sources

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Controlled delivery of membrane proteins to artificial lipid bilayers by nystatin-ergosterol modulated vesicle fusion

, 2006
The study of ion channels and other membrane proteins and their potential use as biosensors and drug screening targets require their reconstitution in an artificial membrane.
Fisher, K.H., Berry, RM, Fisher, K H, Berry, R M, de Planque, MR, de Planque, M R R, Sandison, ME, Watts, A, Mendes, G P, Morgan, Hywel, Watts, A., Berry, Richard, Sandison, M E, de Planque, M.R.R., Sandison, Mairi E., Mendes, GP, Zagnoni, M, Zagnoni, Michele, Watts, Anthony, Berry, R.M., Morgan, H, Mendes, G.P., Fisher, KH   +22 more
core   +1 more source