Results 21 to 30 of about 527,570 (257)
LegC3, an effector protein from Legionella pneumophila, inhibits homotypic yeast vacuole fusion in vivo and in vitro. [PDF]
PLoS ONE, 2013 During infection, the intracellular pathogenic bacterium Legionella pneumophila causes an extensive remodeling of host membrane trafficking pathways, both in the construction of a replication-competent vacuole comprised of ER-derived vesicles and plasma ...
Terry L Bennett +5 more
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Fusogenic pairings of vesicle-associated membrane proteins (VAMPs) and plasma membrane t-SNAREs--VAMP5 as the exception. [PDF]
PLoS ONE, 2010 Intracellular vesicle fusion is mediated by the interactions of SNARE (soluble N-ethylmaleimide-sensitive factor attachment protein receptor) proteins on vesicles (v-SNAREs) and on target membranes (t-SNAREs).
Nazarul Hasan, Deborah Corbin, Chuan Hu
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BMC Biology, 2008 Background To study the organization and interaction with the fusion domain (or fusion peptide, FP) of the transmembrane domain (TMD) of influenza virus envelope glycoprotein for its role in membrane fusion which is also essential in the cellular ...
Lin Chi-Hui +4 more
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Computational insights into the membrane fusion mechanism of SARS-CoV-2 at the cellular level
Computational and Structural Biotechnology Journal, 2021 The membrane fusion mechanism of SARS-CoV-2 offers an attractive target for the development of small molecule antiviral inhibitors. Fusion involves an initial binding of the crown-like trimeric spike glycoproteins of SARS-CoV-2 to the receptor ...
Jimin Wang +7 more
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Frontiers in Molecular Neuroscience, 2017 Membrane fusion is one of the most fundamental physiological processes in eukaryotes for triggering the fusion of lipid and content, as well as the neurotransmission.
Zhiwei Yang +7 more
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FEBS Letters, 2007 Membrane fusion of enveloped viruses with cellular membranes is mediated by viral glycoproteins (GP). Interaction of GP with cellular receptors alone or coupled to exposure to the acidic environment of endosomes induces extensive conformational changes in the fusion protein which pull two membranes into close enough proximity to trigger bilayer fusion.
Weissenhorn, Winfried +2 more
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Mechanics of membrane fusion [PDF]
Nature Structural & Molecular Biology, 2008 Diverse membrane fusion reactions in biology involve close contact between two lipid bilayers, followed by the local distortion of the individual bilayers and reformation into a single, merged membrane. We consider the structures and energies of the fusion intermediates identified in experimental and theoretical work on protein-free lipid bilayers.
Chernomordik, Leonid V +1 more
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Implication des peptides de fusion des glycoprotéines de fusion virales de classe I dans la fusion membranaire [PDF]
Biotechnologie, Agronomie, Société et Environnement, 2007 The implication of fusion peptides of class I viral fusion glycoproteins in the membrane fusion. Viral infection involves fusion between the viral envelope and the target cell plasmic membrane.
Brasseur R. +3 more
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Spatial regulation of membrane fusion controlled by modification of phosphoinositides. [PDF]
PLoS ONE, 2010 Membrane fusion plays a central role in many cell processes from vesicular transport to nuclear envelope reconstitution at mitosis but the mechanisms that underlie fusion of natural membranes are not well understood.
Fabrice Dumas +5 more
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, 2014 Entry of enveloped viruses is mediated by viral glycoproteins that catalyze fusion of viral and cellular membranes. These viral glycoproteins need to be activated which leads to extensive conformational changes that trigger the insertion or attachment of a fusion peptide in or to cellular target membranes thus bridging two bilayers.
Hock, M., Weissenhorn, W.
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