SNAREs-SAP: SNARE Proteins Identification With PSSM Profiles [PDF]
Frontiers in Genetics, 2021 Soluble N-ethylmaleimide sensitive factor activating protein receptor (SNARE) proteins are a large family of transmembrane proteins located in organelles and vesicles.
Zixiao Zhang +6 more
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The Sec1/Munc18 protein Vps45 regulates cellular levels of its SNARE binding partners Tlg2 and Snc2 in Saccharomyces cerevisiae. [PDF]
PLoS ONE, 2012 Intracellular membrane trafficking pathways must be tightly regulated to ensure proper functioning of all eukaryotic cells. Central to membrane trafficking is the formation of specific SNARE (soluble N-ethylmeleimide-sensitive factor attachment protein ...
Scott G Shanks +4 more
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Drunken lipid membranes, not drunken SNARE proteins, promote fusion in a model of neurotransmitter release [PDF]
Frontiers in Molecular Neuroscience, 2022 Alcohol affects many neuronal proteins that are upstream or down-stream of synaptic vesicle fusion and neurotransmitter release. Less well studied is alcohol’s effect on the fusion machinery including SNARE proteins and lipid membranes.
Robert E. Coffman +6 more
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SNARE Proteins Are Required for Macroautophagy. [PDF]
Cell, 2011 Macroautophagy mediates the degradation of long-lived proteins and organelles via the de novo formation of double-membrane autophagosomes that sequester cytoplasm and deliver it to the vacuole/lysosome; however, relatively little is known about autophagosome biogenesis.
Nair U +15 more
europepmc +6 more sources
SNARE protein mimicry by an intracellular bacterium. [PDF]
PLoS Pathogens, 2008 Many intracellular pathogens rely on host cell membrane compartments for their survival. The strategies they have developed to subvert intracellular trafficking are often unknown, and SNARE proteins, which are essential for membrane fusion, are possible ...
Cédric Delevoye +6 more
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Mechanisms of SNARE proteins in membrane fusion. [PDF]
Nat Rev Mol Cell Biol, 2023 Soluble N-ethylmaleimide-sensitive factor attachment protein receptors (SNAREs) are a family of small conserved eukaryotic proteins that mediate membrane fusion between organelles and with the plasma membrane. SNAREs are directly or indirectly anchored to membranes.
Jahn R, Cafiso DC, Tamm LK.
europepmc +5 more sources
Intracellular bacteria encode inhibitory SNARE-like proteins. [PDF]
PLoS ONE, 2009 Pathogens use diverse molecular machines to penetrate host cells and manipulate intracellular vesicular trafficking. Viruses employ glycoproteins, functionally and structurally similar to the SNARE proteins, to induce eukaryotic membrane fusion ...
Fabienne Paumet +7 more
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Effect of resveratrol on SNARE proteins expression and insulin resistance in skeletal muscle of diabetic rats [PDF]
Iranian Journal of Basic Medical Sciences, 2019 Objective(s): Soluble N-ethylmaleimide-sensitive factor attachment protein receptor (SNARE) complex proteins are involved in membrane trafficking. The expression of isoforms of SNAP-23, syntaxin-4, and VAMP-2 is significantly done in skeletal muscles ...
Azam Rezaei Farimani +5 more
doaj +2 more sources
Two coiled-coil domains of Chlamydia trachomatis IncA affect membrane fusion events during infection. [PDF]
PLoS ONE, 2013 Chlamydia trachomatis replicates in a parasitophorous membrane-bound compartment called an inclusion. The inclusions corrupt host vesicle trafficking networks to avoid the degradative endolysosomal pathway but promote fusion with each other in order to ...
Erik Ronzone, Fabienne Paumet
doaj +6 more sources
SNARE-CNN: a 2D convolutional neural network architecture to identify SNARE proteins from high-throughput sequencing data [PDF]
PeerJ Computer Science, 2019 Deep learning has been increasingly and widely used to solve numerous problems in various fields with state-of-the-art performance. It can also be applied in bioinformatics to reduce the requirement for feature extraction and reach high performance. This
Nguyen Quoc Khanh Le, Van-Nui Nguyen
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