Results 41 to 50 of about 48,939 (293)

Structural and Functional Analysis of the CAPS SNARE-Binding Domain Required for SNARE Complex Formation and Exocytosis

open access: yesCell Reports, 2019
Summary: Exocytosis of synaptic vesicles and dense-core vesicles requires both the Munc13 and CAPS (Ca2+-dependent activator proteins for secretion) proteins.
Hao Zhou   +5 more
doaj   +1 more source

SNARE VTI13 plays a unique role in endosomal trafficking pathways associated with the vacuole and is essential for cell wall organization and root hair growth in arabidopsis [PDF]

open access: yes, 2014
Background and Aims: Root hairs are responsible for water and nutrient uptake from the soil and their growth is responsive to biotic and abiotic changes in their environment.
Domozych, David S.   +2 more
core   +1 more source

Alternate routes to the cell surface underpin insulin-regulated membrane trafficking of GLUT4 [PDF]

open access: yes, 2015
Insulin-stimulated delivery of glucose transporters (GLUT4) from specialized intracellular GLUT4 storage vesicles (GSVs) to the surface of fat and muscle cells is central to whole-body glucose.
Bryant, Nia J.   +3 more
core   +3 more sources

The rab3A-22A chimera prevents sperm exocytosis by stabilizing open fusion pores [PDF]

open access: yes, 2016
At the final stage of exocytotis, a fusion pore opens between the plasma and a secretory vesicle membranes; typically, when the pore dilates the vesicle releases its cargo.
Bustos, Matias Alberto   +5 more
core   +1 more source

Revisiting interaction specificity reveals neuronal and adipocyte Munc18 membrane fusion regulatory proteins differ in their binding interactions with partner SNARE Syntaxins. [PDF]

open access: yesPLoS ONE, 2017
The efficient delivery of cellular cargo relies on the fusion of cargo-carrying vesicles with the correct membrane at the correct time. These spatiotemporal fusion events occur when SNARE proteins on the vesicle interact with cognate SNARE proteins on ...
Michelle P Christie   +7 more
doaj   +1 more source

An ancestral secretory apparatus in the protozoan parasite Giardia intestinalis [PDF]

open access: yes, 2003
The protozoan parasite Giardia intestinalis belongs to one of the earliest diverged eukaryotic lineages. This is also reflected in a simple intracellular organization, as Giardia lacks common subcellular compartments such as mitochondria, peroxisomes ...
Hehl, Adrian B.   +7 more
core   +1 more source

SNARE Proteins

open access: yes, 2021
Different types of SNAREs, General structural features of SNARES and The general mode of their ...
openaire   +1 more source

Cell polarity and patterning by PIN trafficking through early endosomal compartments in Arabidopsis thaliana [PDF]

open access: yes, 2013
PIN-FORMED (PIN) proteins localize asymmetrically at the plasma membrane and mediate intercellular polar transport of the plant hormone auxin that is crucial for a multitude of developmental processes in plants.
De Rycke, Riet   +8 more
core   +5 more sources

A SNARE-like protein from Solanum lycopersicum increases salt tolerance by modulating vesicular trafficking in tomato

open access: yesFrontiers in Plant Science, 2023
Intracellular vesicular trafficking ensures the exchange of lipids and proteins between endomembrane compartments. This is relevant under high salinity conditions, since both the removal of transporters and ion channels from the plasma membrane and the ...
Josselyn Salinas-Cornejo   +4 more
doaj   +1 more source

SNARE Complex–Associated Proteins and Alcohol [PDF]

open access: yesAlcoholism: Clinical and Experimental Research, 2019
Alcohol addiction causes major health problems throughout the world, causing numerous deaths and incurring a huge economic burden to society. To develop an intervention for alcohol addiction, it is necessary to identify molecular target(s) of alcohol and associated molecular mechanisms of alcohol action.
openaire   +2 more sources

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