Results 21 to 30 of about 686 (210)
The SNARE protein family of Leishmania major [PDF]
BMC Genomics, 2006 Abstract Background Leishmania major is a protozoan parasite with a highly polarised cell shape that depends upon endocytosis and exocytosis from a single area of the plasma membrane, the flagellar pocket.
Besteiro, S. +2 more
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The role of snare proteins in cortical development
Developmental Neurobiology, 2022 AbstractNeural communication in the adult nervous system is mediated primarily through chemical synapses, where action potentials elicit Ca2+ signals, which trigger vesicular fusion and neurotransmitter release in the presynaptic compartment.
Vadisiute, A +6 more
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SNARE-CNN: a 2D convolutional neural network architecture to identify SNARE proteins from high-throughput sequencing data [PDF]
PeerJ Computer Science, 2019 Deep learning has been increasingly and widely used to solve numerous problems in various fields with state-of-the-art performance. It can also be applied in bioinformatics to reduce the requirement for feature extraction and reach high performance. This
Nguyen Quoc Khanh Le, Van-Nui Nguyen
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EpsinR Is an Adaptor for the SNARE Protein Vti1b [PDF]
Molecular Biology of the Cell, 2004 EpsinR is a clathrin-coated vesicle (CCV)-associated protein that binds to vti1b, suggesting that it may be a vti1b-selective adaptor. Depletion of epsinR to undetectable levels in HeLa cells using siRNA causes vti1b to redistribute from the perinuclear region to the cell periphery, but vti1a also redistributes in epsinR-depleted cells, and both vti ...
Hirst, J +4 more
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The mesoscale organization of syntaxin 1A and SNAP25 is determined by SNARE–SNARE interactions
eLife, 2021 SNARE proteins have been described as the effectors of fusion events in the secretory pathway more than two decades ago. The strong interactions between SNARE domains are clearly important in membrane fusion, but it is unclear whether they are involved ...
Jasmin Mertins +5 more
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A Pearson Based Feature Compressing Model for SNARE Protein Classification
IEEE Access, 2020 SNARE proteins are a group of proteins that drive the biological fusion of two membranes. It is important to identify them accurately, because malfunction of the SNARE proteins can lead to a lot of diseases.
Guilin Li
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Reconciling the regulatory role of Munc18 proteins in SNARE-complex assembly
IUCrJ, 2014 Membrane fusion is essential for human health, playing a vital role in processes as diverse as neurotransmission and blood glucose control. Two protein families are key: (1) the Sec1p/Munc18 (SM) and (2) the soluble N-ethylmaleimide-sensitive attachment ...
Asma Rehman +5 more
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Molecular Dynamics Simulations of the Proteins Regulating Synaptic Vesicle Fusion
Membranes, 2023 Neuronal transmitters are packaged in synaptic vesicles (SVs) and released by the fusion of SVs with the presynaptic membrane (PM). An inflow of Ca2+ into the nerve terminal triggers fusion, and the SV-associated protein Synaptotagmin 1 (Syt1) serves as ...
Maria Bykhovskaia
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eLife, 2017 Intracellular membrane fusion mediates diverse processes including cell growth, division and communication. Fusion involves complex formation between SNARE proteins anchored to adjacent membranes.
Matthias Karnahl +4 more
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Role of SNAREs in Neurodegenerative Diseases
Cells, 2021 Neurodegenerative diseases are pathologies of the central and peripheral nervous systems characterized by loss of brain functions and problems in movement which occur due to the slow and progressive degeneration of cellular elements.
Azzurra Margiotta
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