Results 11 to 20 of about 29,299 (286)
Mechanisms of SNARE proteins in membrane fusion. [PDF]
Nat Rev Mol Cell Biol, 2023 Soluble N-ethylmaleimide-sensitive factor attachment protein receptors (SNAREs) are a family of small conserved eukaryotic proteins that mediate membrane fusion between organelles and with the plasma membrane. SNAREs are directly or indirectly anchored to membranes.
Jahn R, Cafiso DC, Tamm LK.
europepmc +7 more sources
Intracellular bacteria encode inhibitory SNARE-like proteins. [PDF]
PLoS ONE, 2009 Pathogens use diverse molecular machines to penetrate host cells and manipulate intracellular vesicular trafficking. Viruses employ glycoproteins, functionally and structurally similar to the SNARE proteins, to induce eukaryotic membrane fusion ...
Fabienne Paumet +7 more
doaj +4 more sources
SNARE Proteins as Signaling Elements [PDF]
, 2013 SNAREs (N-ethylmaleimide-sensitive factor adaptor protein receptors) are small polypeptides (∼200–400 amino acid) which are characterized by a particular domain, the SNARE motif that can form a coiled-coil structure via hetero-oligomeric interactions. These protein interactions are highly stable leading to the formation of the so-called SNARE complex ...
Ul Rehman R., Di Sansebastiano G. P.
core +5 more sources
The Sec1/Munc18 protein Vps45 regulates cellular levels of its SNARE binding partners Tlg2 and Snc2 in Saccharomyces cerevisiae. [PDF]
PLoS ONE, 2012 Intracellular membrane trafficking pathways must be tightly regulated to ensure proper functioning of all eukaryotic cells. Central to membrane trafficking is the formation of specific SNARE (soluble N-ethylmeleimide-sensitive factor attachment protein ...
Scott G Shanks +4 more
doaj +3 more sources
SNARE Proteins Synaptobrevin, SNAP-25, and Syntaxin Are Involved in Rapid and Slow Endocytosis at Synapses [PDF]
Cell Reports, 2013 Rapid endocytosis, which takes only a few seconds, is widely observed in secretory cells. Although it is more efficient in recycling vesicles than in slow clathrin-mediated endocytosis, its underlying mechanism, thought to be clathrin independent, is ...
Jianhua Xu +7 more
doaj +2 more sources
SNARE Proteins And SNARE Regulators Mediate Aquaporin2 Exocytosis In Renal Cells [PDF]
The FASEB Journal, 2008 Aim: The expression and the functional involvement of SNARE proteins and SNARE‐regulating proteins (Munc18b and Munc18c) in catalyzing aquaporin 2 vesicles fusion at the apical membrane is investigated in a mouse cortical collecting duct cell line. Methods: Localization of SNARE and SNARE‐regulating proteins was performed using a ...
PROCINO, Giuseppe +6 more
openaire +2 more sources
Microdomains of SNARE Proteins in the Plasma Membrane [PDF]
, 2013 Exocytosis is catalyzed by the engagement of SNARE proteins embedded in the plasma membrane with complementary SNAREs in the membrane of trafficking vesicles undergoing exocytosis. In most cells studied so far, SNAREs are not randomly distributed across the plasma membrane but are clustered and segregated in discrete membrane domains of defined size ...
van den Bogaart, G., Lang, T., Jahn, R.
openaire +6 more sources
SNARE Proteins Are Required for Macroautophagy. [PDF]
Cell, 2011 Macroautophagy mediates the degradation of long-lived proteins and organelles via the de novo formation of double-membrane autophagosomes that sequester cytoplasm and deliver it to the vacuole/lysosome; however, relatively little is known about autophagosome biogenesis.
Nair U +15 more
europepmc +6 more sources
The role of snare proteins in cortical development. [PDF]
Dev Neurobiol, 2022 AbstractNeural communication in the adult nervous system is mediated primarily through chemical synapses, where action potentials elicit Ca2+ signals, which trigger vesicular fusion and neurotransmitter release in the presynaptic compartment.
Vadisiute A +6 more
europepmc +4 more sources
SNARE proteins: zip codes in vesicle targeting? [PDF]
Biochem J, 2022 Membrane traffic in eukaryotic cells is mediated by transport vesicles that bud from a precursor compartment and are transported to their destination compartment where they dock and fuse.
Koike S, Jahn R.
europepmc +3 more sources