Results 41 to 50 of about 840,592 (294)

Crystallization of the oligopeptide-binding protein AppA from Bacillus subtilis [PDF]

, 2004
AppA is the membrane-anchored extracellular receptor component of an ABC transporter responsible for the uptake of oligopeptides into Bacillus subtilis.
Blagova, E, Brannigan, J A, Chambers, J, Levdikov, V M, Pattenden, R J, Wilkinson, A J, Wright, L   +6 more
core   +1 more source

Influenza Virus-cell Fusion Inhibition Assay

Bio-Protocol, 2013
During viral infection to host cells, several viruses undergo the process of endocytosis and pH-dependent fusion. By fusion of viral membrane with host cellular membrane, the viral core invades to host cytoplasm.
Mayo Yasugi, Kazuyoshi Ikuta
doaj   +1 more source

A Suitable Membrane Distance Regulated by the RBD_ACE2 Interaction is Critical for SARS‐CoV‐2 Spike‐Mediated Viral Invasion

Advanced Science, 2023
The receptor‐binding domain (RBD) of spike recognizing the receptor angiotensin‐converting enzyme 2 (ACE2) initiates membrane fusion between severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) and cell membrane.
Mengdan Wu, Wei Li, Sheng Lin, Jiaqi Fan, Lele Cui, Yijuan Xiang, Kaiyu Li, Linwei Tang, Yanping Duan, Zimin Chen, Fanli Yang, Weiwei Shui, Guangwen Lu, Ying Lai   +13 more
doaj   +1 more source

Structural analysis of a trimeric assembly of the mitochondrial dynamin-like GTPase Mgm1. [PDF]

, 2020
The fusion of inner mitochondrial membranes requires dynamin-like GTPases, Mgm1 in yeast and OPA1 in mammals, but how they mediate membrane fusion is poorly understood.
Hu, Junjie, Li, Lei, Lou, Zhiyong, Nunnari, Jodi, Qi, Yuanbo, Rao, Zihe, Ricketson, Derek, Sarsam, Reta, Subramanian, Kelly, Wong, Melissa, Wu, Lijie, Yan, Liming, Yu, Caiting, Zhao, Jinghua   +13 more
core  

Fusogenic structural changes in arenavirus glycoproteins are associated with viroporin activity.

PLoS Pathogens, 2023
Many enveloped viruses enter host cells by fusing with acidic endosomes. The fusion activity of multiple viral envelope glycoproteins does not generally affect viral membrane permeability.
You Zhang, Joanne York, Melinda A Brindley, Jack H Nunberg, Gregory B Melikyan   +4 more
doaj   +1 more source

Tension-voltage relationship in membrane fusion and its implication in exocytosis [PDF]

, 1998
In this study, new methods are used to control cellular membrane tension to evaluate the role it plays in electrofusion. The data show that membrane tension present during the application of an electric field facilitates electro-induced membrane fusion ...
Augustine, Rothman, de Kruijff, Siegel, Rosenheck, Sutton, Montal, Neumann, Senda, Gabriel, Teissie, Teissie, Dimitrov, Rand, Monck, Chandler, Vitale, Needham, Teissie, Blangero, Abidor, Cruzeiro-Hansson, Lopez, Stulen, Abidor, Bryant, Stenger, Wu, Oberhauser, Weber, Mayer, Alvarez de Toledo, Rosenheck   +32 more
core   +1 more source

Membrane Fusion

Bioscience Reports, 2000
The fusion of biological membranes results in two bilayer-based membranes merging into a single membrane. In this process the lipids have to undergo considerable rearrangement. The nature of the intermediates that are formed during this rearrangement has been investigated. Certain fusion proteins facilitate this process. In many cases short segments of
openaire   +2 more sources

Mapping the evolution of mitochondrial complex I through structural variation

FEBS Letters, EarlyView.
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin, Tingting Chen, James A. Letts   +2 more
wiley   +1 more source

SARS-CoV-2 spike fusion peptide trans interaction with phosphatidylserine lipid triggers membrane fusion for viral entry

mBio
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike is the fusion machine for host cell entry. Still, the mechanism by which spike protein interacts with the target lipid membrane to facilitate membrane fusion during entry is not fully ...
Puspangana Singh, Purba Pahari, Srija Mukherjee, Sharmistha Karmakar, Markus Hoffmann, Taraknath Mandal, Dibyendu Kumar Das   +6 more
doaj   +1 more source

Physico-chemical requirements and kinetics of membrane fusion of flavivirus-like particles. [PDF]

, 2015
Flaviviruses deliver their RNA genome into the host-cell cytoplasm by fusing their lipid envelope with a cellular membrane. Expression of the flavivirus pre-membrane and envelope glycoprotein genes in the absence of other viral genes results in the ...

core   +1 more source