Results 11 to 20 of about 556,464 (304)

Negative regulation of syntaxin4/SNAP-23/VAMP2-mediated membrane fusion by Munc18c In Vitro [PDF]

open access: yes, 2008
Background: Translocation of the facilitative glucose transporter GLUT4 from an intracellular store to the plasma membrane is responsible for the increased rate of glucose transport into fat and muscle cells in response to insulin.
Nia J Bryant   +17 more
core   +1 more source

Differential cargo mobilisation within Weibel-Palade bodies after transient fusion with the plasma membrane. [PDF]

open access: yes, 2014
Inflammatory chemokines can be selectively released from Weibel-Palade bodies (WPBs) during kiss-and-run exocytosis. Such selectivity may arise from molecular size filtering by the fusion pore, however differential intra-WPB cargo re-mobilisation ...
Knipe, Laura   +19 more
core   +1 more source

Coassembly of Mgm1 isoforms requires cardiolipin and mediates mitochondrial inner membrane fusion [PDF]

open access: yes, 2009
Two dynamin-related protein (DRP) families are essential for fusion of the outer and inner mitochondrial membranes, Fzo1 (yeast)/Mfn1/Mfn2 (mammals) and Mgm1 (yeast)/Opa1 (mammals), respectively.
Stahlberg, Henning   +11 more
core   +1 more source

Towards Understanding the Angiomotin Membrane Fusion Activity

open access: yes, 2021
Angiomotins (Amot) are a family of adaptor proteins that regulate cellular differentiation and proliferation signaling. These cellular events are linked to the initiation of invasive ductal carcinoma, the most common form of breast cancer.
Brenner, Evans   +2 more
core   +1 more source

Secretory vesicles are preferentially targeted to areas of low molecular SNARE density [PDF]

open access: yes, 2012
Intercellular communication is commonly mediated by the regulated fusion, or exocytosis, of vesicles with the cell surface. SNARE (soluble N-ethymaleimide sensitive factor attachment protein receptor) proteins are the catalytic core of the secretory ...
Weiping Lu (120665)   +32 more
core   +1 more source

Virus membrane fusion [PDF]

open access: yesFEBS Letters, 2007
Membrane fusion of enveloped viruses with cellular membranes is mediated by viral glycoproteins (GP). Interaction of GP with cellular receptors alone or coupled to exposure to the acidic environment of endosomes induces extensive conformational changes in the fusion protein which pull two membranes into close enough proximity to trigger bilayer fusion.
Weissenhorn, Winfried   +2 more
openaire   +4 more sources

Mechanics of membrane fusion [PDF]

open access: yesNature Structural & Molecular Biology, 2008
Diverse membrane fusion reactions in biology involve close contact between two lipid bilayers, followed by the local distortion of the individual bilayers and reformation into a single, merged membrane. We consider the structures and energies of the fusion intermediates identified in experimental and theoretical work on protein-free lipid bilayers.
Chernomordik, Leonid V   +1 more
openaire   +2 more sources

Structure and function of bacterial dynamin-like proteins [PDF]

open access: yes, 2012
Membrane dynamics are essential for numerous cellular processes in eukaryotic and prokaryotic cells. In eukaryotic cells, membrane fusion and fission are often catalyzed by large GTPases of the dynamin protein family. These proteins couple GTP hydrolysis
Bramkamp, Marc
core   +1 more source

The yeast vacuolar membrane proteome [PDF]

open access: yes, 2009
Transport of solutes between the cytosol and the vacuolar lumen is of crucial importance for various functions of vacuoles, including ion homeostasis; detoxification; storage of different molecules such as amino acids, phosphate, and calcium ions; and ...
Poolman, Bert,   +18 more
core   +1 more source

Functional analysis of the Bunyamwera orthobunyavirus Gc glycoprotein [PDF]

open access: yes, 2009
The virion glycoproteins Gn and Gc of Bunyamwera orthobunyavirus (BUNV, family Bunyaviridae) are encoded by the M RNA genome segment and have roles in both viral attachment and membrane fusion.
Elliott, Richard Michael   +9 more
core   +1 more source

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