Results 11 to 20 of about 527,570 (257)
Viruses, 2020 Protein-mediated membrane fusion is a highly regulated biological process essential for cellular and organismal functions and infection by enveloped viruses. During viral entry the membrane fusion reaction is catalyzed by specialized protein machinery on
Mark A. Benhaim, Kelly K. Lee
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Current Opinion in Cell Biology, 2002 Fusion of biological membranes is governed by physical principles but it is unclear whether the transition states are primarily determined by lipid physics or by protein-lipid interactions. Recent advances in the field include the physical description of bilayer fusion, particularly new models beyond continuum models and the role of the SNARE proteins.
Jahn, R., Grubmueller, H.
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Phospholipases and Membrane Curvature: What Is Happening at the Surface?
Membranes, 2023 In this revision work, we emphasize the close relationship between the action of phospholipases and the modulation of membrane curvature and curvature stress resulting from this activity.
María Laura Fanani +1 more
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Two coiled-coil domains of Chlamydia trachomatis IncA affect membrane fusion events during infection. [PDF]
PLoS ONE, 2013 Chlamydia trachomatis replicates in a parasitophorous membrane-bound compartment called an inclusion. The inclusions corrupt host vesicle trafficking networks to avoid the degradative endolysosomal pathway but promote fusion with each other in order to ...
Erik Ronzone, Fabienne Paumet
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Membrane Binding of α-Synuclein Stimulates Expansion of SNARE-Dependent Fusion Pore
Frontiers in Cell and Developmental Biology, 2021 SNARE-dependent membrane fusion is essential for neurotransmitter release at the synapse. Recently, α-synuclein has emerged as an important regulator for membrane fusion. Misfolded α-synuclein oligomers are potent fusion inhibitors. However, the function
Ryan Khounlo +6 more
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Scientific Reports, 2023 Membrane fusion is an essential step for the entry of enveloped viruses, such as human immunodeficiency virus and influenza virus, into the host cell, often triggered by the binding of membrane proteins on the viral envelope to host cell membrane ...
Hiroto Furukawa +3 more
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Membrane tension and membrane fusion [PDF]
Current Opinion in Structural Biology, 2015 Diverse cell biological processes that involve shaping and remodeling of cell membranes are regulated by membrane lateral tension. Here we focus on the role of tension in driving membrane fusion. We discuss the physics of membrane tension, forces that can generate the tension in plasma membrane of a cell, and the hypothesis that tension powers ...
Michael M, Kozlov +1 more
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TRIM67 regulates exocytic mode and neuronal morphogenesis via SNAP47
Cell Reports, 2021 Summary: Neuronal morphogenesis involves dramatic plasma membrane expansion, fueled by soluble N-ethylmaleimide-sensitive factor attachment protein eceptors (SNARE)-mediated exocytosis.
Fabio L. Urbina +6 more
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A virus-encoded cell-cell fusion machine dependent on surrogate adhesins. [PDF]
PLoS Pathogens, 2008 The reovirus fusion-associated small transmembrane (FAST) proteins function as virus-encoded cellular fusogens, mediating efficient cell-cell rather than virus-cell membrane fusion. With ectodomains of only approximately 20-40 residues, it is unclear how
Jayme Salsman +3 more
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Cell Reports, 2019 Summary: Intracellular vesicle fusion is mediated by soluble N-ethylmaleimide sensitive factor attachment protein receptors (SNAREs) and Sec1/Munc18 (SM) proteins. It is generally accepted that membrane fusion occurs when the vesicle and target membranes
Shailendra S. Rathore +7 more
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