Results 181 to 190 of about 20,740 (205)

Establishment and molecular characterization of a novel leukemic cell line with Philadelphia chromosome expressing p230 BCR/ABL fusion protein.

Cancer research, 1995
The cell line AR230 was established from the peripheral blood mononuclear cells of a patient with chronic myeloid leukemia and t(9;22) translocation bearing a variant type of BCR/ABL rearrangement. AR230 expresses a BCR/ABL fusion protein with a molecular mass of 230 kilodaltons (kDa) due to the insertion of 180 amino acids encoded by 3' exons of BCR ...
H, Wada, S, Mizutani, J, Nishimura, Y, Usuki, M, Kohsaki, M, Komai, H, Kaneko, S, Sakamoto, D, Delia, A, Kanamaru   +9 more
openaire   +1 more source

Two bcr/abl fusion gene products, P210bcr/abl and P190bcr/abl, are equally sensitive to the protein tyrosine phosphatase of mature granulocytes.

International journal of hematology, 1992
Two bcr/abl fusion gene products with tyrosine kinase activity have been found in two phenotypes of Philadelphia chromosome (Ph1)-positive leukemia. P210bcr/abl (P210) is associated with Ph1-positive chronic myelogenous leukemia (CML), while P190bcr/abl is associated with Ph1-positive acute leukemia.
J, Nishimura, J, Okamura, K, Shibata, H, Takahira, Y, Yufu, S, Kato, J, Hirata, T, Umemura, H, Nawata   +8 more
openaire   +1 more source

CeO2/MXene heterojunction-based ultrasensitive electrochemiluminescence biosensing for BCR-ABL fusion gene detection combined with dual-toehold strand displacement reaction for signal amplification

Biosensors and Bioelectronics, 2022
Ningke Fan, Wei Cheng, Min Zhao
exaly  

[Signal transduction BCR-ABL fusion protein: analysis of BCR-ABL functional domains].

[Rinsho ketsueki] The Japanese journal of clinical hematology, 1998
T, Tauchi, S, Okabe, K, Oyashiki, K, Sotoyama   +3 more
openaire   +1 more source

BCR‐ABL Fusion Protein

2008
openaire   +1 more source

Regulation of the c-Abl and Bcr–Abl tyrosine kinases

Nature Reviews Molecular Cell Biology, 2004
Oliver D Hantschel, Giulio Superti-Furga
exaly  

Mechanisms of BCR–ABL in the pathogenesis of chronic myelogenous leukaemia

Nature Reviews Cancer, 2005
Ruibao Ren
exaly  

Flying under the radar: the new wave of BCR–ABL inhibitors

Nature Reviews Drug Discovery, 2007
Hagop M Kantarjian, Jorge Cortes
exaly  

Second generation inhibitors of BCR-ABL for the treatment of imatinib-resistant chronic myeloid leukaemia

Nature Reviews Cancer, 2007
Sandra W Cowan-Jacob, Andreas Hochhaus
exaly  

BCR-ABL gene mutations in relation to clinical resistance of Philadelphia-chromosome-positive leukaemia to STI571: a prospective study

Lancet, The, 2002
Nikolas von Bubnoff
exaly