Results 191 to 200 of about 1,010,581 (327)

Phase-separating fusion proteins drive cancer by upsetting transcription regulation. [PDF]

Genome Biol
Farahi N, Lazar T, Tompa P, Mészáros B, Pancsa R.   +4 more
europepmc   +1 more source

SmallTalk: a novel small‐sized fusion tag for peptide expression and purification

FEBS Open Bio, EarlyView.
The SmallTalk fusion tag allows for the efficient expression and purification of soluble recombinant proteins or peptides in Escherichia coli. Testing with SmallTalk‐GFP confirmed that the proteins were soluble and folded correctly, while SmallTalk‐Bin1b maintained its antimicrobial activity against various bacterial isolates. This streamlined workflow
Atika Tariq, Nestor G. Casillas‐Vega, Alma Gomez‐Loredo, Xristo Zarate   +3 more
wiley   +1 more source

Autophagosome marker, LC3, is released extracellularly via several distinct pathways

FEBS Open Bio, EarlyView.
This study establishes a novel HiBiT‐tagging system for ultrasensitive detection of LC3, revealing multiple pathways for its extracellular secretion. It demonstrates that LC3 is released via both autophagy‐dependent and ‐independent mechanisms, including a novel route for nonlipidated LC3‐I.
Koki Saito, Masashi Arakawa, Koki Maeda, Eiji Morita   +3 more
wiley   +1 more source

Engineering Fusion Proteins for Nanomedicine-Based Cytokine Therapy. [PDF]

Bioconjug Chem
de Dreu A, de Bruin K, Hokke AM, Schrijver DP, Beelen DNH, Verhalle LM, Clavijo Perez MC, Anbergen T, Versteeg I, Maas R, Zwolsman RC, Grao-Roldán C, Bartelet B, Trines MM, Hoorn D, Ros G, Toner YC, Kluza E, Beldman T, Pérez-Medina C, Netea MG, Merkx M, van der Meel R, Mulder WJM.   +23 more
europepmc   +1 more source

Hu14.18-IL2 Fusion Protein EMD 273063 [PDF]

, 2020
National Cancer Institute
openalex   +1 more source

ATP13A2 is involved in intracellular polyamine transport in lung epithelial cells

FEBS Open Bio, EarlyView.
Spermidine transport in lung epithelial cells involves the polyamine transporter ATP13A2. Cell proliferation is associated with the upregulation of ATP13A2. Polyamines are present in all living cells and are implicated in various crucial cellular processes such as proliferation, apoptosis and autophagy.
Yuta Hatori, Kohei Kawabata, Takanori Kubo, Takeo Kitazawa, Sae Kanai, Madoka Iwashita, Ami Hayashi, Hiroyuki Nishi, Mikihisa Takano   +8 more
wiley   +1 more source

Identification of engineered IMGT Fc variants in IMGT/mAb-DB, a database of therapeutic antibodies and fusion proteins. [PDF]

MAbs
Manso T, Sanou G, Nousias C, Maalem I, Boutin F, Giudicelli V, Duroux P, Lefranc MP, Kossida S.   +8 more
europepmc   +1 more source

Elimination of tumor by CD47/PD-L1 dual-targeting fusion protein that engages innate and adaptive immune responses

, 2017
Boning Liu, Huaizu Guo, Jin Xu, Ting Qin, Qingcheng Guo, Nana Gu, Dapeng Zhang, Weizhu Qian, Jianxin Dai, Sheng Hou, Hao Wang, Yajun Guo   +11 more
openalex   +1 more source

TMC4 localizes to multiple taste cell types in the mouse taste papillae

FEBS Open Bio, EarlyView.
Transmembrane channel‐like 4 (TMC4), a voltage‐dependent chloride channel, plays a critical role in amiloride‐insensitive salty taste transduction. TMC4 is broadly expressed in all mature taste cell types, suggesting a possible involvement of multiple cell types in this pathway.
Momo Murata, Yoshikazu Saito, Yoichi Kasahara, Wataru Fujii, Takumi Misaka, Tomiko Asakura, Masataka Narukawa   +6 more
wiley   +1 more source

Expression, immunogenicity and clinical significance analysis of thyroid‑stimulating hormone receptor fusion proteins. [PDF]

Mol Med Rep
Chen X, Chen H.
europepmc   +1 more source