Magnetically Guided Mechanoactive Mineralization Scaffolds for Enhanced Bone Regeneration
A 3D‐printed ‘rebar‐concrete’ inspired scaffold (PGS‐P@MGel) synergizes spontaneous biomineralization with magneto‐mechanical stimulation through PDA@Fe3O4‐embedded hydrogel. This dual biointerface activates Piezo1/β‐catenin/YAP mechanotransduction axis, enhancing BMSCs osteogenesis and angiogenesis simultaneously.
Xuran Guo+10 more
wiley +1 more source
Enhanced depletion of MLL-fusion proteins in acute leukemia: potential for improved therapeutic outcomes. [PDF]
Che N+6 more
europepmc +1 more source
Supervariate Gel Transforms into Various Biominerals in Salt Solutions
It is revealed that common calcium‐based biominerals can form from a stable, non‐toxic ‘supervariate’ gel. This tunable gel selectively yields calcite or hydroxyapatite in carbonate/phosphate solutions, while CaCl₂ facilitates the formation of dihydrate calcium pyrophosphate, which converts to hydroxyapatite upon drying. These findings provide insights
Xinxue Tang+12 more
wiley +1 more source
Second-Generation Phage Lambda Platform Employing SARS-CoV-2 Fusion Proteins as a Vaccine Candidate. [PDF]
Catala A+3 more
europepmc +1 more source
Achieving Chemical Recognition, Recycling, and Circularity With Radical Nanostructures
Here, innovative 3D radical nanostructures based on 4,4′‐dicyano‐2,2′‐biphenylene‐fused tetrazolinyl radical, fabricated on interdigitated gold‐SiO2 hybrid surfaces are presented. They retain their magnetic properties, their morphology and size can can tune, selectively remove them from specific substrate regions using distilled water, and return the ...
Arkaprava Das+10 more
wiley +1 more source
Structural analysis of S-ring composed of FliFG fusion proteins in marine Vibrio polar flagellar motor. [PDF]
Takekawa N+10 more
europepmc +1 more source
A Vertically‐Stacked Optoelectronic Sensor for Localized Hemodynamics Monitoring
This work introduces a hemodynamics monitoring sensor that features vertically stacked microLEDs and a heterogeneously integrated photodetector. The vertically stacked microLEDs enable localized measurements, and by designing the interoptode distance according to the depth of the target region, this vertically stacked optoelectronic sensor is ...
Taeyeon Lee+9 more
wiley +1 more source
Interchain disulfide engineering enables the efficient production of functional HLA-DQ-Fc fusion proteins. [PDF]
Aisihaer X, Guo H, Liu C.
europepmc +1 more source
A Universal Biomimetic Approach for Making Artificial Antigen‐Presenting Cells for T Cell Activation
This study shows a biomimetic silica microcapsule (SMC) fabrication method under mild conditions for making artificial antigen‐presenting cells (aAPCs). Inspired by marine biomineralization, peptide‐mediated biosilicification enables silica shell formation on emulsion templates. The resulting SMCs possess a core–shell structure, controlled fluorescence
Fei Hou+5 more
wiley +1 more source