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Fusion of classifiers for predicting protein–protein interactions
Neurocomputing, 2005Prediction of protein-protein interaction is a difficult and an important problem in biology. In this paper, we describe a very general method for predicting protein-protein interactions. The interaction mining approach is demonstrated by building a learning system based on experimentally validated protein-protein interactions in the human gastric ...
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Fusion protein with a toxin and scaffold protein
2020The present invention relates to the field of structural biology and drug discovery. More specifically, the present invention relates to novel fusion proteins, their uses and methods in three-dimensional structural analysis of macromolecules, such as X-ray crystallography and high-resolution Cryo-EM, and their use in structure-based drug design and ...
Steyaert, Jan, Pardon, Els, Vranken, Wim
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Design of fusion proteins for biocatalysis
The use of enzymes to convert substrates into valuable products has been an integral part of biocatalysis. However, some reactions are energy-demanding that requires the use of NAD(P)H to proceed. This NAD(P)H can be costly impeding the progress of enzyme usage at a bigger scale.Beyzanur, Celebi+3 more
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Mapping protein-protein interactions with alkaline phosphatase fusion proteins
2001Publisher Summary This chapter describes a convenient and versatile method for determining the molecular recognition properties of SH3 domains, using bacterial alkaline phosphatase as a fusion protein. A variety of proteins or peptides have been fused to the N terminus of alkaline phosphatase (AP) by genetic engineering, including antibody chains and
Brian K. Kay, Montarop Yamabhai
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Nanooncology: The future of cancer diagnosis and therapy
Ca-A Cancer Journal for Clinicians, 2013Avnesh S Thakor
exaly
Translating cancer genomes and transcriptomes for precision oncology
Ca-A Cancer Journal for Clinicians, 2016Sameek Roychowdhury, Arul M Chinnaiyan
exaly
Protein fusions: bioseparation and application
Trends in Biotechnology, 1991openaire +2 more sources