Results 81 to 90 of about 13,524,575 (343)
Structural and biochemical analysis of a B12 superbinder
FEBS Letters, EarlyView.BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices +3 more
wiley +1 more source
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
FEBS Letters, EarlyView.Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
Design of Intense Neutron Source for Fusion Material Study and the Role of Universities [PDF]
, 1993 Need and requirement for the intense neutron source for fusion materials study have been discussed for many years. Recently, international climate has been becoming gradually maturing to consider this problem more seriously because of the recognition of ...
ISHINO, Shiori
core
A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma
FEBS Letters, EarlyView.Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos +9 more
wiley +1 more source
Studies on D-3^He Fusion in LHD [PDF]
, 1996 In LHD ( Large Helical Device ) studies on realization of D-D fusion burning has been carried out, where tritium burning is out of this plan. We propose experiments on D-^3He fusion in this plan. This fueled fusion has the reaction cross-section as large
YAMAZAKI, Kozo +12 more
core
Computational Mechanism Design for Information Fusion within Sensor Networks
, 2006 Conventional centralised information fusion and control architectures will be challenged by developments in sensor networks that allow sophisticated autonomous sensors, owned by different stakeholders with individual goals, to interact and share ...
S. Reece +16 more
core +1 more source
Nuclear diagnostics for Inertial Confinement Fusion (ICF) plasmas
, 2020 Submitted for publication in Plasma Physics and Controlled FusionThe field of nuclear diagnostics for Inertial Confinement Fusion (ICF) is broadly reviewed from its beginning in the seventies to present day.
Frenje, Johan A.
core +1 more source
Preface to the Special Issue: Strategic Opportunities for Fusion Energy [PDF]
, 2016 The Journal of Fusion Energy provides a forum for discussion of broader policy and planning issues that play a crucial role in energy fusion programs.
Mauel, M. E. +3 more
core +1 more source
FEBS Letters, EarlyView.Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley +1 more source
Advances in Meteorology, 2019 Temperature changes have a major impact on all aspects of human society and have attracted global attention. The scarcity of observation data and the inaccuracy of the models make obtaining accurate temperature distributions a challenge.
Yu Liu +4 more
doaj +1 more source