Results 221 to 230 of about 41,327 (291)

Enterococcus faecalis Extracellular Vesicles Deliver the Bacterial GTPase Obg to Hijack mTOR Signalling in Hepatocellular Carcinoma

open access: yesJournal of Extracellular Vesicles, Volume 15, Issue 6, June 2026.
E. faecalis is enriched in HCC tissue and can promote liver tumourigenesis by activating mTOR signalling pathway. Obg derived from E. faecalis extracellular vesicles (EVs) is a GTPase physically interacts with mTOR, and acts as an interkingdom activator of mTOR. EF‐Obg expression level in HCC tissue correlates with poor prognosis in HCC patients.
Ning Ma   +18 more
wiley   +1 more source

High Versus Low Radiographic Burden Odontogenic Sinusitis: Culture, Histopathology, and Patient‐Reported Outcomes

open access: yesLaryngoscope Investigative Otolaryngology, Volume 11, Issue 3, June 2026.
This study investigated clinical, histopathologic, and symptomatic differences between odontogenic sinusitis patients with high versus low radiographic burden. High radiographic burden disease was associated with older age and increased tissue inflammation, while significant postoperative symptom improvement was only observed in the high‐burden cohort.
Landon E. Ebbert   +4 more
wiley   +1 more source

Unraveling Oral Dysbiosis: Microbial Complexity in Common Oral Diseases

open access: yesMicrobiologyOpen, Volume 15, Issue 3, June 2026.
The oral microbiome undergoes dynamic establishment from birth, maturing into a resilient ecosystem. Perturbation of this homeostasis—driven by dietary, immunological, and anatomical factors—triggers dysbiosis, which underpins the pathogenesis of major oral diseases, including dental caries, periodontal disease, salivary gland disorders, oral mucosal ...
Zixi Kang   +8 more
wiley   +1 more source

Nanoparticle‐Based Strategies to Combat Multidrug‐Resistant Bacteria: Mechanisms, Applications, and Future Perspectives

open access: yesMicrobiologyOpen, Volume 15, Issue 3, June 2026.
Nanobiotics offer a promising strategy to combat antimicrobial resistance (AMR) and multidrug‐resistant (MDR) bacteria. Nanoparticles overcome traditional resistance mechanisms through unique physicochemical properties and multivalent interactions.
Akmal Zubair   +3 more
wiley   +1 more source

Fecal Microbiome Alterations in Colorectal Cancer: A Systematic Review of Compositional Changes and Microbial Biomarkers

open access: yesMicrobiologyOpen, Volume 15, Issue 3, June 2026.
Gut microbiome plays a crucial role in colorectal cancer development. The advanced sequencing techniques have the potential to complement current non‐invasive methods for early diagnosis and prevention of colorectal cancer. This includes conducting studies with robust statistical power and consistent, replicable methodologies, taking into consideration
Parvin Askari   +10 more
wiley   +1 more source

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